Cell cryopreservation is an essential tool for managing variability associated with human immune cell stability by locking in viability and providing researchers with reliable, on-demand human immune cells for basic research or cell therapy development.
Cryopreservation is a technique to preserve living cells, tissues, or organisms. This process involves rapidly cooling biological material to halt all metabolic activity and preserve it in a state of suspended animation. Cryoprotective agents minimize the damaging effects of ice formation and cell dehydration, allowing for long-term storage of valuable biological samples.
It is important to have optimized processes and expertise to ensure cell viability and functionality during cryopreservation, as some cell types are more sensitive to the cryopreservation process than others. For cryopreservation to be successful, the freezing, storage, and thawing protocol must be carried out correctly.
Improper cryopreservation can lead to a significant loss of cell viability and function, which has made scientists cautious about using cryopreserved products in the past. Charles River has spent the past decade perfecting our cryopreservation protocols to ensure maximum viability and functionality. As a result, we marketed the first commercially available cryopreserved leukopaks.
When done right, cryopreservation simplifies shipping and storage logistics while maintaining cell quality and stability, helps to ensure product consistency, and allows scheduling flexibility when planning and coordinating downstream processing activities. Cell cryopreservation expertise at Charles River includes:
Available products include:
To learn more, visit the Charles River Cell Solutions storefront on Science Exchange.