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Girish Sardana

Research Scientist - Ontario Cancer Biomarker Network
Toronto Ontario, CA
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Position - Company  
Biomarker Research and Development Associate - Ontario Cancer Biomarker Network

• Responsible for client relations management, project coordination and sourcing of new projects and collaborations
• Assisting in the coordination and preparation of grant proposals to public funding bodies
• Conducted laboratory research projects for clients and coordinated with collaborators on delivering project objectives
• Trained contract research staff in research methods utilized for specific projects
• Managed online marketing tools such as company website and presence on social networking platforms

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Jan 2009 - Jan 2010
Post-Doctoral Fellow - Samuel Lunenfeld Research Institute

• Performed an immunodiagnostic evaluation of the kallikrein family of proteins as urine markers for prostate cancer
• Contributed to an OICR grant application for an international prospective validation study of biomarkers for prostate cancer

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Sep 2008 - Dec 2008
PhD Student - University of Toronto

Thesis: Identification and validation of novel biomarkers for the detection of prostate cancer through proteomic analysis of cell culture conditioned medium


Supervisor: Dr. Eleftherios P. Diamandis

Department of Laboratory Medicine and Pathobiology
Advanced Centre for Detection of Cancer
Mt. Sinai Hospital
Laboratory of Dr. E. P. Diamandis

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Sep 2003 - Sep 2008
Intellectual Property Analyst - The Innovations Group

• Assisted Commercialization Managers in conducting technology and market assessments and performing due diligence and prior art research on intellectual property relating to diagnostic and therapeutic applications

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2008 - 2008
Research Scientist - Ontario Cancer Biomarker Network 2005 - Present
Research Scientist, BioSpecimens - Ontario Cancer Biomarker Network

• Responsible for the management of the OCBN biorepository, including the receipt, processing, storage, and distribution of biological specimens, quality assurance processes, and its financial management
• Developed, maintained and updated Department SOP’s
• Trained and supervised biobank staff in sample processing, data entry and biosafety
• Managed and executed Multi-plex ELISA projects utilizing the Luminex and MesoScale Discovery platforms
• Co-ordinated and communicated with clients in meeting their needs for biorepository and Multi-plex ELISA services

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Jan 2010 - Present
Degree - University  
Ph.D., Clinical Biochemistry - University of Toronto

Proteomic analysis of prostate cancer cell line conditioned media for biomarker discovery

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2003 - 2008
PhD, Clinical Biochemistry - University of Toronto

Thesis: Identification and Validation of Novel Candidates for the Early Detection of Prostate Cancer Through Proteomic Analysis of Prostate Cancer Cell Culture Conditioned Media

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2003 - 2008
B.Sc.H, Life Sciences - Queen's University of Kingston 1999 - 2003
Bsc. Hons., Life Sciences - Queen's University

Honours Thesis: Generation of Mutant Constructs at Tyrosine 1062 in the MEN2B and Wild Type Forms of the Short Isoform of RET

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1999 - 2003
OSSD, Life Sciences - Mentor College 1994 - 1999
Publication Info
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival. Cawthorn TR, Moreno JC, Dharsee M, Tran-Thanh D, Ackloo S, Zhu PH, Sardana G and 12 others PLoS One. 7(2):e30992. doi: 10.1371/journal.pone.0030992. February 20, 2012. View on PubMed.
Identification and quantification of peptides and proteins secreted from prostate epithelial cells by unbiased liquid chromatography tandem mass spectrometry using goodness of fit and analysis of variance. Florentinus AK, Bowden P, Sardana G, Diamandis EP, Marshall JG J Proteomics. 75(4):1303-17. doi: 10.1016/j.jprot.2011.11.002. February 2, 2012. View on PubMed.
Determination of the association of urine prostate specific antigen levels with anthropometric variables in children aged 5-14 years. Efthimiou I, Ferentinos G, Tsachouridis G, Sardana G, Diamandis E Int Braz J Urol. 36(2):202-7; discussion 207-8. April 2010. View on PubMed.
The kallikrein family of proteins as urinary biomarkers for the detection of prostate cancer. Sardana G, Diamandis EP Clin Biochem. 42(13-14):1483-6. doi: 10.1016/j.clinbiochem.2009.06.015. June 25, 2009. View on PubMed.
Emerging biomarkers for the diagnosis and prognosis of prostate cancer. Sardana G, Dowell B, Diamandis EP Clin Chem. 54(12):1951-60. doi: 10.1373/clinchem.2008.110668. October 16, 2008. View on PubMed.
Proteomic analysis of conditioned media from the PC3, LNCaP, and 22Rv1 prostate cancer cell lines: discovery and validation of candidate prostate cancer biomarkers. Sardana G, Jung K, Stephan C, Diamandis EP J Proteome Res. 7(8):3329-38. doi: 10.1021/pr8003216. June 26, 2008. View on PubMed.
Discovery of candidate tumor markers for prostate cancer via proteomic analysis of cell culture-conditioned medium. Sardana G, Marshall J, Diamandis EP Clin Chem. 53(3):429-37. doi: 10.1373/clinchem.2006.077370. January 26, 2007. View on PubMed.
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