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Cristian Ruse

Proteomics Core Manager - Cold Spring Harbor Laboratory

Position - Company  
Proteomics Core Manager - Cold Spring Harbor Laboratory Mar 2009 - Present
Degree - University  
Ph.D., Biophysics - Case Western Reserve University School of Medicine 1998 - 2003
Publication Info
Silencing of microRNA families by seed-targeting tiny LNAs. Obad S, dos Santos CO, Petri A, Heidenblad M, Broom O, Ruse C, Fu C and 8 others Nat Genet. 43(4):371-8. doi: 10.1038/ng.786. March 20, 2011. View on PubMed.
dFMRP and Caprin, translational regulators of synaptic plasticity, control the cell cycle at the Drosophila mid-blastula transition. Papoulas O, Monzo KF, Cantin GT, Ruse C, Yates JR 3rd, Ryu YH, Sisson JC Development. 137(24):4201-9. doi: 10.1242/dev.055046. November 10, 2010. View on PubMed.
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Fekairi S, Scaglione S, Chahwan C, Taylor ER, Tissier A, Coulon S, Dong MQ and 6 others Cell. 138(1):78-89. doi: 10.1016/j.cell.2009.06.029. July 10, 2009. View on PubMed.
Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS. Wang J, Farr GW, Zeiss CJ, Rodriguez-Gil DJ, Wilson JH, Furtak K, Rutkowski DT and 6 others Proc Natl Acad Sci U S A. 106(5):1392-7. doi: 10.1073/pnas.0813045106. February 3, 2009. View on PubMed.
Proteomics by mass spectrometry: approaches, advances, and applications. Yates JR, Ruse CI, Nakorchevsky A Annu Rev Biomed Eng. 11:49-79. doi: 10.1146/annurev-bioeng-061008-124934. 2009. View on PubMed.
Colander: a probability-based support vector machine algorithm for automatic screening for CID spectra of phosphopeptides prior to database search. Lu B, Ruse CI, Yates JR 3rd J Proteome Res. 7(8):3628-34. doi: 10.1021/pr8001194. June 19, 2008. View on PubMed.
Motif-specific sampling of phosphoproteomes. Ruse CI, McClatchy DB, Lu B, Cociorva D, Motoyama A, Park SK, Yates JR 3rd J Proteome Res. 7(5):2140-50. doi: 10.1021/pr800147u. May 2008. View on PubMed.
Improving protein identification sensitivity by combining MS and MS/MS information for shotgun proteomics using LTQ-Orbitrap high mass accuracy data. Lu B, Motoyama A, Ruse C, Venable J, Yates JR 3rd Anal Chem. 80(6):2018-25. doi: 10.1021/ac701697w. March 15, 2008. View on PubMed.
Anion and cation mixed-bed ion exchange for enhanced multidimensional separations of peptides and phosphopeptides. Motoyama A, Xu T, Ruse CI, Wohlschlegel JA, Yates JR 3rd Anal Chem. 79(10):3623-34. doi: 10.1021/ac062292d. May 15, 2007. View on PubMed.
Automatic validation of phosphopeptide identifications from tandem mass spectra. Lu B, Ruse C, Xu T, Park SK, Yates J 3rd Anal Chem. 79(4):1301-10. doi: 10.1021/ac061334v. February 15, 2007. View on PubMed.
Protein kinase A dependent phosphorylation activates Mg2+ efflux in the basolateral region of the liver. Cefaratti C, Ruse C Mol Cell Biochem. 297(1-2):209-14. doi: 10.1007/s11010-006-9325-1. September 26, 2006. View on PubMed.
Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase. Shimogawa MM, Graczyk B, Gardner MK, Francis SE, White EA, Ess M, Molk JN and 7 others Curr Biol. 16(15):1489-501. doi: 10.1016/j.cub.2006.06.063. August 8, 2006. View on PubMed.
Automated ultra-high-pressure multidimensional protein identification technology (UHP-MudPIT) for improved peptide identification of proteomic samples. Motoyama A, Venable JD, Ruse CI, Yates JR 3rd Anal Chem. 78(14):5109-18. doi: 10.1021/ac060354u. July 15, 2006. View on PubMed.
Intregrated analysis of the human cardiac transcriptome, proteome and phosphoproteome. Ruse CI, Tan FL, Kinter M, Bond M Proteomics. 4(5):1505-16. doi: 10.1002/pmic.200300682. May 2004. View on PubMed.
Site-specific quantitation of protein nitration using liquid chromatography/tandem mass spectrometry. Willard BB, Ruse CI, Keightley JA, Bond M, Kinter M Anal Chem. 75(10):2370-6. May 15, 2003. View on PubMed.
Quantitative dynamics of site-specific protein phosphorylation determined using liquid chromatography electrospray ionization mass spectrometry. Ruse CI, Willard B, Jin JP, Haas T, Kinter M, Bond M Anal Chem. 74(7):1658-64. April 1, 2002. View on PubMed.
The highly conserved COOH terminus of troponin I forms a Ca2+-modulated allosteric domain in the troponin complex. Jin JP, Yang FW, Yu ZB, Ruse CI, Bond M, Chen A Biochemistry. 40(8):2623-31. February 27, 2001. View on PubMed.
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