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Robin Yates

Assistant Professor - University of Calgary

Position - Company  
Assistant Professor - University of Calgary Apr 2008 - Present
Degree - University  
PhD, Biomed Sci - Cornell University 2003 - 2006
BVSc(hons), DVM equivalent - Queensland Cyber Infrastructure Foundation Ltd 1996 - 2001
BSc - Queensland Cyber Infrastructure Foundation Ltd 1995 - 1999
Publication Info
Phagosomal proteolysis in dendritic cells is modulated by NADPH oxidase in a pH-independent manner. Rybicka JM, Balce DR, Chaudhuri S, Allan ER, Yates RM EMBO J. 31(4):932-44. doi: 10.1038/emboj.2011.440. December 13, 2011. View on PubMed.
In vitro and in vivo transfection of primary phagocytes via microbubble-mediated intraphagosomal sonoporation. Lemmon JC, McFarland RJ, Rybicka JM, Balce DR, McKeown KR, Krohn RM, Matsunaga TO, Yates RM J Immunol Methods. 371(1-2):152-8. doi: 10.1016/j.jim.2011.06.001. August 31, 2011. View on PubMed.
Alternative activation of macrophages by IL-4 enhances the proteolytic capacity of their phagosomes through synergistic mechanisms. Balce DR, Li B, Allan ER, Rybicka JM, Krohn RM, Yates RM Blood. :. doi: 10.1182/blood-2011-01-328906. August 16, 2011. View on PubMed.
Development of a novel, cell-based chemical screen to identify inhibitors of intraphagosomal lipolysis in macrophages. VanderVen BC, Hermetter A, Huang A, Maxfield FR, Russell DG, Yates RM Cytometry A. 77(8):751-60. doi: 10.1002/cyto.a.20911. August 2010. View on PubMed.
NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes. Rybicka JM, Balce DR, Khan MF, Krohn RM, Yates RM Proc Natl Acad Sci U S A. 107(23):10496-501. doi: 10.1073/pnas.0914867107. June 8, 2010. View on PubMed.
Antiviral antibodies target adenovirus to phagolysosomes and amplify the innate immune response. Zaiss AK, Vilaysane A, Cotter MJ, Clark SA, Meijndert HC, Colarusso P, Yates RM, Petrilli V, Tschopp J, Muruve DA J Immunol. 182(11):7058-68. doi: 10.4049/jimmunol.0804269. June 1, 2009. View on PubMed.
Intraphagosomal measurement of the magnitude and duration of the oxidative burst. VanderVen BC, Yates RM, Russell DG Traffic. 10(4):372-8. doi: 10.1111/j.1600-0854.2009.00877.x. April 2009. View on PubMed.
Recording phagosome maturation through the real-time, spectrofluorometric measurement of hydrolytic activities. Yates RM, Hermetter A, Russell DG Methods Mol Biol. 531:157-71. doi: 10.1007/978-1-59745-396-7_11. 2009. View on PubMed.
Real-time spectrofluorometric assays for the lumenal environment of the maturing phagosome. Yates RM, Russell DG Methods Mol Biol. 445:311-25. doi: 10.1007/978-1-59745-157-4_20. 2008. View on PubMed.
Mycobacterium tuberculosis and the environment within the phagosome. Rohde K, Yates RM, Purdy GE, Russell DG Immunol Rev. 219:37-54. doi: 10.1111/j.1600-065X.2007.00547.x. October 2007. View on PubMed.
TLR signalling and phagosome maturation: an alternative viewpoint. Russell DG, Yates RM Cell Microbiol. 9(4):849-50. doi: 10.1111/j.1462-5822.2007.00920.x. March 8, 2007. View on PubMed.
Macrophage activation downregulates the degradative capacity of the phagosome. Yates RM, Hermetter A, Taylor GA, Russell DG Traffic. 8(3):241-50. doi: 10.1111/j.1600-0854.2006.00528.x. March 2007. View on PubMed.
Toll-like receptors and phagosome maturation. Russell DG, Yates RM Nat Immunol. 8(3):217; author reply 217-8. doi: 10.1038/ni0307-217a. March 2007. View on PubMed.
Adherent and invasive Escherichia coli is associated with granulomatous colitis in boxer dogs. Simpson KW, Dogan B, Rishniw M, Goldstein RE, Klaessig S, McDonough PL, German AJ and 8 others Infect Immun. 74(8):4778-92. doi: 10.1128/IAI.00067-06. August 2006. View on PubMed.
Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4. Yates RM, Russell DG Immunity. 23(4):409-17. doi: 10.1016/j.immuni.2005.09.007. October 2005. View on PubMed.
The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity. Yates RM, Hermetter A, Russell DG Traffic. 6(5):413-20. doi: 10.1111/j.1600-0854.2005.00284.x. May 2005. View on PubMed.
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