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Kate Mc Innerney

Research Associate - Functional Genomics Core Facility

Position - Company  
Research Associate - Functional Genomics Core Facility Montana State University

We run Affymetrix and Nimblegen arrays. For Affy expression array experiments, we provide sample prep, hybridization and scanning, as well as basic data analysis using open-source software. For Nimblegen, we accept ds cDNA and provide single-color labeling, hybridization, scanning, normalization with NimbleScan software, and basic data analysis. We are happy to assist with data submission to GEO. Our services are detailed at http://cores.montana.edu/genomics.

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Jun 2004 - Present
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Publication Info
Heterogeneity in Pseudomonas aeruginosa biofilms includes expression of ribosome hibernation factors in the antibiotic-tolerant subpopulation and hypoxia-induced stress response in the metabolically active population. Williamson KS, Richards LA, Perez-Osorio AC, Pitts B, McInnerney K, Stewart PS, Franklin MJ J Bacteriol. 194(8):2062-73. doi: 10.1128/JB.00022-12. April 2012. View on PubMed.
Pneumocystis elicits a STAT6-dependent, strain-specific innate immune response and airway hyperresponsiveness. Swain SD, Meissner NN, Siemsen DW, McInnerney K, Harmsen AG Am J Respir Cell Mol Biol. 46(3):290-8. doi: 10.1165/rcmb.2011-0154OC. March 2012. View on PubMed.
Genotypic and phenotypic variation in Pseudomonas aeruginosa reveals signatures of secondary infection and mutator activity in certain cystic fibrosis patients with chronic lung infections. Warren AE, Boulianne-Larsen CM, Chandler CB, Chiotti K, Kroll E, Miller SR, Taddei F and 5 others Infect Immun. 79(12):4802-18. doi: 10.1128/IAI.05282-11. December 2011. View on PubMed.
Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes. Secor PR, James GA, Fleckman P, Olerud JE, McInnerney K, Stewart PS BMC Microbiol. 11:143. doi: 10.1186/1471-2180-11-143. June 21, 2011. View on PubMed.
Type-I IFN signaling suppresses an excessive IFN-gamma response and thus prevents lung damage and chronic inflammation during Pneumocystis (PC) clearance in CD4 T cell-competent mice. Meissner N, Swain S, McInnerney K, Han S, Harmsen AG Am J Pathol. 176(6):2806-18. doi: 10.2353/ajpath.2010.091158. April 15, 2010. View on PubMed.
Extraction of RNA from Ca-alginate-encapsulated yeast for transcriptional profiling. Kruckeberg AL, Nagarajan S, McInnerney K, Rosenzweig F Anal Biochem. 391(2):160-2. doi: 10.1016/j.ab.2009.04.032. August 15, 2009. View on PubMed.
A Candida albicans early stage biofilm detachment event in rich medium. Sellam A, Al-Niemi T, McInnerney K, Brumfield S, Nantel A, Suci PA BMC Microbiol. 9:25. doi: 10.1186/1471-2180-9-25. February 2, 2009. View on PubMed.
New two-photon activated photodynamic therapy sensitizers induce xenograft tumor regressions after near-IR laser treatment through the body of the host mouse. Starkey JR, Rebane AK, Drobizhev MA, Meng F, Gong A, Elliott A, McInnerney K, Spangler CW Clin Cancer Res. 14(20):6564-73. doi: 10.1158/1078-0432.CCR-07-4162. October 15, 2008. View on PubMed.
Reduced nicotinamide adenine dinucleotide phosphate oxidase-independent resistance to Aspergillus fumigatus in alveolar macrophages. Cornish EJ, Hurtgen BJ, McInnerney K, Burritt NL, Taylor RM, Jarvis JN, Wang SY, Burritt JB J Immunol. 180(10):6854-67. May 15, 2008. View on PubMed.
Transcriptome analysis of infection of the archaeon Sulfolobus solfataricus with Sulfolobus turreted icosahedral virus. Ortmann AC, Brumfield SK, Walther J, McInnerney K, Brouns SJ, van de Werken HJ, Bothner B, Douglas T, van de Oost J, Young MJ J Virol. 82(10):4874-83. doi: 10.1128/JVI.02583-07. March 12, 2008. View on PubMed.
Comparative transcriptome profiling of near-isogenic barley (Hordeum vulgare) lines differing in the allelic state of a major grain protein content locus identifies genes with possible roles in leaf senescence and nitrogen reallocation. Jukanti AK, Heidlebaugh NM, Parrott DL, Fischer IA, McInnerney K, Fischer AM New Phytol. 177(2):333-49. doi: 10.1111/j.1469-8137.2007.02270.x. November 19, 2007. View on PubMed.
Yeast genomic expression patterns in response to low-shear modeled microgravity. Sheehan KB, McInnerney K, Purevdorj-Gage B, Altenburg SD, Hyman LE BMC Genomics. 8:3. doi: 10.1186/1471-2164-8-3. January 3, 2007. View on PubMed.
Steam-girdling of barley (Hordeum vulgare) leaves leads to carbohydrate accumulation and accelerated leaf senescence, facilitating transcriptomic analysis of senescence-associated genes. Parrott DL, McInnerney K, Feller U, Fischer AM New Phytol. 176(1):56-69. doi: 10.1111/j.1469-8137.2007.02158.x. 2007. View on PubMed.
Microarray analysis of IFN-gamma response genes in astrocytes. Halonen SK, Woods T, McInnerney K, Weiss LM J Neuroimmunol. 175(1-2):19-30. doi: 10.1016/j.jneuroim.2006.02.015. April 21, 2006. View on PubMed.
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