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Ute Hochgeschwender

Director - Provider 5
Durham North Carolina, US

Position - Company  
Director - Provider 5 Provider D Mar 2008 - Present
Degree - University  
MA, Philosophy - Free University of Berlin 1976 - 1983
M.D., Neurobiology - Free University of Berlin 1976 - 1983
Publication Info
Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice. Manion CV, Hochgeschwender U, Edmundson AB, Hugli TE, Gabaglia CR Rheumatology (Oxford). 50(7):1244-9. doi: 10.1093/rheumatology/ker089. July 2011. View on PubMed.
Genetic modifications of mouse proopiomelanocortin peptide processing. Costa JL, Forbes S, Brennan MB, Hochgeschwender U Mol Cell Endocrinol. 336(1-2):14-22. doi: 10.1016/j.mce.2010.12.032. April 10, 2011. View on PubMed.
Impaired neonatal survival of pro-opiomelanocortin null mutants. Saedler K, Hochgeschwender U Mol Cell Endocrinol. 336(1-2):6-13. doi: 10.1016/j.mce.2010.12.005. April 10, 2011. View on PubMed.
A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum. Armstrong CL, Chung SH, Armstrong JN, Hochgeschwender U, Jeong YG, Hawkes R J Comp Neurol. 517(4):524-38. doi: 10.1002/cne.22167. December 1, 2009. View on PubMed.
Plasma alpha-melanocyte-stimulating hormone: sex differences and correlations with obesity. Donahoo WT, Hernandez TL, Costa JL, Jensen DR, Morris AM, Brennan MB, Hochgeschwender U, Eckel RH Metabolism. 58(1):16-21. doi: 10.1016/j.metabol.2008.07.028. January 2009. View on PubMed.
Transgenic mice expressing dominant-negative bright exhibit defects in B1 B cells. Nixon JC, Ferrell S, Miner C, Oldham AL, Hochgeschwender U, Webb CF J Immunol. 181(10):6913-22. November 15, 2008. View on PubMed.
Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors. Karpac J, Czyzewska K, Kern A, Brush RS, Anderson RE, Hochgeschwender U Am J Physiol Endocrinol Metab. 295(2):E446-55. doi: 10.1152/ajpendo.00762.2007. June 17, 2008. View on PubMed.
Null mutant mouse models of somatostatin and cortistatin, and their receptors. Zeyda T, Hochgeschwender U Mol Cell Endocrinol. 286(1-2):18-25. doi: 10.1016/j.mce.2007.11.029. May 14, 2008. View on PubMed.
Somatostatin receptor subtype 4 couples to the M-current to regulate seizures. Qiu C, Zeyda T, Johnson B, Hochgeschwender U, de Lecea L, Tallent MK J Neurosci. 28(14):3567-76. doi: 10.1523/JNEUROSCI.4679-07.2008. April 2, 2008. View on PubMed.
Proopiomelanocortin heterozygous and homozygous null mutant mice develop pituitary adenomas. Karpac J, Ostwald D, Li GY, Bui S, Hunnewell P, Brennan MB, Hochgeschwender U Cell Mol Biol (Noisy-le-grand). 52(2):47-52. May 30, 2006. View on PubMed.
Impairment in motor learning of somatostatin null mutant mice. Zeyda T, Diehl N, Paylor R, Brennan MB, Hochgeschwender U Brain Res. 906(1-2):107-14. July 6, 2001. View on PubMed.
Identifying transcribed sequences in arrayed bacteriophage or cosmid libraries. Hochgeschwender U, Brennan MB Curr Protoc Hum Genet. Chapter 6:Unit 6.2. doi: 10.1002/0471142905.hg0602s00. May 2001. View on PubMed.
Pronociceptive actions of dynorphin maintain chronic neuropathic pain. Wang Z, Gardell LR, Ossipov MH, Vanderah TW, Brennan MB, Hochgeschwender U, Hruby VJ, Malan TP Jr, Lai J, Porreca F J Neurosci. 21(5):1779-86. March 1, 2001. View on PubMed.
Generation of dynorphin knockout mice. Sharifi N, Diehl N, Yaswen L, Brennan MB, Hochgeschwender U Brain Res Mol Brain Res. 86(1-2):70-5. January 31, 2001. View on PubMed.
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Yaswen L, Diehl N, Brennan MB, Hochgeschwender U Nat Med. 5(9):1066-70. doi: 10.1038/12506. September 1999. View on PubMed.
The impact of genomics on mammalian neurobiology. Hochgeschwender U, Brennan MB Bioessays. 21(2):157-63. doi: 10.1002/(SICI)1521-1878(199902)21:2<157::AID-BIES9>3.0.CO;2-0. February 1999. View on PubMed.
Mouse knockouts rule OK. Hochgeschwender U, Brennan MB Nature. 375(6532):543. doi: 10.1038/375543b0. June 15, 1995. View on PubMed.
Redundant genes? Hochgeschwender U, Brennan MB Nat Genet. 8(3):219-20. doi: 10.1038/ng1194-219. November 1994. View on PubMed.
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