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Jin-Moo Lee

Associate Professor, Neurology Attending Physician, Stroke Service at Barnes-Jewish Hospital Director, Cerebrovascular Disease Section - Washington University School of Medicine View Biosketch →

Position - Company  
Associate Professor, Neurology Attending Physician, Stroke Service at Barnes-Jewish Hospital Director, Cerebrovascular Disease Section - Washington University School of Medicine 2012 - Present
Degree - University  
Medical Degree - Weill Cornell Medical College Cornell University 1993 - 1996
B.A. - Yale University 1985 - 1992
Publication Info
Ultrasmall superparamagnetic iron oxides enhanced MR imaging in rats with experimentally induced endometriosis. Lee HJ, Lee HJ, Lee JM, Chang Y, Woo ST Magn Reson Imaging. :. doi: 10.1016/j.mri.2012.02.020. July 2012. View on PubMed.
The effects of Photofrin-mediated photodynamic therapy on the modulation of EGFR in esophageal squamous cell carcinoma cells. Yang PW, Hung MC, Hsieh CY, Tung EC, Wang YH, Tsai JC, Lee JM Lasers Med Sci. :. doi: 10.1007/s10103-012-1119-y. May 15, 2012. View on PubMed.
Retinoic acid alleviates Con A-induced hepatitis and differentially regulates effector production in NKT cells. Lee KA, Song YC, Kim GY, Choi G, Lee YS, Lee JM, Kang CY Eur J Immunol. :. doi: 10.1002/eji.201142322. May 14, 2012. View on PubMed.
Biodegradation behavior of silk fibroin membranes in repairing tympanic membrane perforations. Lee OJ, Lee JM, Kim JH, Kim J, Kweon H, Jo YY, Park CH J Biomed Mater Res A. :. doi: 10.1002/jbm.a.33308. May 12, 2012. View on PubMed.
Hemimasticatory spasm treated with microvascular decompression of the trigeminal nerve. Chon KH, Lee JM, Koh EJ, Choi HY Acta Neurochir (Wien). :. doi: 10.1007/s00701-012-1360-y. May 12, 2012. View on PubMed.
Anti-cancer drug-loaded gliadin nanoparticles induce apoptosis in breast cancer cells. Muhammad G, Kim JE, Lee JM, Ku BR, Chung BH, Chung BG Langmuir. :. doi: 10.1021/la300691n. May 8, 2012. View on PubMed.
Therapeutic effect of high-intensity focused ultrasound combined with transarterial chemoembolisation for hepatocellular carcinoma smaller than 5 cm: comparison with transarterial chemoembolisation monotherapy--preliminary observations. Kim J, Chung DJ, Jung SE, Cho SH, Hahn ST, Lee JM Br J Radiol. :. doi: 10.1259/bjr/32750755. May 2, 2012. View on PubMed.
Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13. Yu MS, Lee J, Lee JM, Kim Y, Chin YW, Jee JG, Keum YS, Jeong YJ Bioorg Med Chem Lett. :. doi: 10.1016/j.bmcl.2012.04.081. April 25, 2012. View on PubMed.
PTHrP isoforms have differing effect on chondrogenic differentiation and hypertrophy of mesenchymal stem cells. Lee JM, Im GI Biochem Biophys Res Commun. :. doi: 10.1016/j.bbrc.2012.04.096. April 25, 2012. View on PubMed.
CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease. Tarawneh R, Lee JM, Ladenson JH, Morris JC, Holtzman DM Neurology. :. doi: 10.1212/WNL.0b013e318248e568. February 22, 2012. View on PubMed.
Pathophysiology and treatment of significant bleeding oesophageal varices. Lee JM Contemp Nurse. 39(2):221-6. doi: 10.5172/conu.2011.221. October 2011. View on PubMed.
Resident-based acute stroke protocol is expeditious and safe. Ford AL, Connor LT, Tan DK, Williams JA, Lee JM, Nassief AM Stroke. 40(4):1512-4. doi: 10.1161/STROKEAHA.108.527770. January 29, 2009. View on PubMed.
Cerebral amyloid angiopathy: progressive disruption of the neurovascular unit. Zipfel GJ, Han H, Ford AL, Lee JM Stroke. 40(3 Suppl):S16-9. doi: 10.1161/STROKEAHA.108.533174. December 8, 2008. View on PubMed.
Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta. Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO and 9 others J Biol Chem. 283(28):19489-98. doi: 10.1074/jbc.M801037200. July 11, 2008. View on PubMed.
Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury. Lee JM, Yan P, Xiao Q, Chen S, Lee KY, Hsu CY, Xu J J Neurosci. 28(12):3141-9. doi: 10.1523/JNEUROSCI.5547-07.2008. March 19, 2008. View on PubMed.
Erythropoietin and its carbamylated derivative prevent the development of experimental diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice. Schmidt RE, Green KG, Feng D, Dorsey DA, Parvin CA, Lee JM, Xiao Q, Brines M Exp Neurol. 209(1):161-70. doi: 10.1016/j.expneurol.2007.09.018. October 29, 2007. View on PubMed.
Hippocampal seizures cause depolymerization of filamentous actin in neurons independent of acute morphological changes. Ouyang Y, Yang XF, Hu XY, Erbayat-Altay E, Zeng LH, Lee JM, Wong M Brain Res. 1143:238-46. doi: 10.1016/j.brainres.2007.01.077. April 27, 2007. View on PubMed.
Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism. Yin KJ, Cirrito JR, Yan P, Hu X, Xiao Q, Pan X, Bateman R and 8 others J Neurosci. 26(43):10939-48. doi: 10.1523/JNEUROSCI.2085-06.2006. October 25, 2006. View on PubMed.
Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ. Yan P, Hu X, Song H, Yin K, Bateman RJ, Cirrito JR, Xiao Q and 6 others J Biol Chem. 281(34):24566-74. doi: 10.1074/jbc.M602440200. August 25, 2006. View on PubMed.
Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes. Chen S, Lee JM, Zeng C, Chen H, Hsu CY, Xu J J Neurochem. 97(3):631-40. doi: 10.1111/j.1471-4159.2006.03774.x. March 8, 2006. View on PubMed.
Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death. Yin KJ, Hsu CY, Hu XY, Chen H, Chen SW, Xu J, Lee JM J Neurosci. 26(8):2290-9. doi: 10.1523/JNEUROSCI.5103-05.2006. February 22, 2006. View on PubMed.
Abeta25-35 alters Akt activity, resulting in Bad translocation and mitochondrial dysfunction in cerebrovascular endothelial cells. Yin KJ, Lee JM, Chen H, Xu J, Hsu CY J Cereb Blood Flow Metab. 25(11):1445-55. doi: 10.1038/sj.jcbfm.9600139. November 2005. View on PubMed.
JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury. Yin KJ, Kim GM, Lee JM, He YY, Xu J, Hsu CY Neurobiol Dis. 20(3):881-9. doi: 10.1016/j.nbd.2005.05.026. July 6, 2005. View on PubMed.
Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter. Xiao Q, Hsu CY, Chen H, Ma X, Xu J, Lee JM Biochem J. 388(Pt 3):913-20. doi: 10.1042/BJ20041739. June 15, 2005. View on PubMed.
Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats. Hartman RE, Lee JM, Zipfel GJ, Wozniak DF Brain Res. 1043(1-2):48-56. doi: 10.1016/j.brainres.2005.02.030. May 10, 2005. View on PubMed.
Matrix metalloproteinase-9 in cerebral-amyloid-angiopathy-related hemorrhage. Lee JM, Yin K, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J J Neurol Sci. 229-230:249-54. doi: 10.1016/j.jns.2004.11.041. March 15, 2005. View on PubMed.
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway. Lee JT, Xu J, Lee JM, Ku G, Han X, Yang DI, Chen S, Hsu CY J Cell Biol. 164(1):123-31. doi: 10.1083/jcb.200307017. January 5, 2004. View on PubMed.
Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy. Lee JM, Yin KJ, Hsin I, Chen S, Fryer JD, Holtzman DM, Hsu CY, Xu J Ann Neurol. 54(3):379-82. doi: 10.1002/ana.10671. September 2003. View on PubMed.
MR imaging enhancement patterns as predictors of hemorrhagic transformation in acute ischemic stroke. Vo KD, Santiago F, Lin W, Hsu CY, Lee Y, Lee JM AJNR Am J Neuroradiol. 24(4):674-9. April 2003. View on PubMed.
Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients. Lee JM, Vo KD, An H, Celik A, Lee Y, Hsu CY, Lin W Ann Neurol. 53(2):227-32. doi: 10.1002/ana.10433. February 2003. View on PubMed.
Temporal relationship between apparent diffusion coefficient and absolute measurements of cerebral blood flow in acute stroke patients. Lin W, Lee JM, Lee YZ, Vo KD, Pilgram T, Hsu CY Stroke. 34(1):64-70. January 2003. View on PubMed.
Neuronal apoptosis after CNS injury: the roles of glutamate and calcium. Zipfel GJ, Babcock DJ, Lee JM, Choi DW J Neurotrauma. 17(10):857-69. doi: 10.1089/neu.2000.17.857. October 2000. View on PubMed.
Time window for clinical effectiveness of mass evacuation in a rat balloon model mimicking an intraparenchymatous hematoma. Lopez Valdes E, Hernandez Lain A, Calandre L, Grau M, Cabello A, Gomez-Escalonilla C J Neurol Sci. 174(1):40-6. March 1, 2000. View on PubMed.
The changing landscape of ischaemic brain injury mechanisms. Lee JM, Zipfel GJ, Choi DW Nature. 399(6738 Suppl):A7-14. June 24, 1999. View on PubMed.
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