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Chu Choi

Research Scientist - Massachusetts Institute of Technology

Position - Company  
Instructor of Medicine - Harvard Medical School Harvard University Jan 2007 - Sep 2008
Postdoctoral Fellow - Harvard Medical School Harvard University Jan 2002 - Jan 2007
Research Scientist - Massachusetts Institute of Technology Sep 2008 - Present
Degree - University  
Ph.D., Chemistry - Boston College 1997 - 2001
S.B., Chemistry - Massachusetts Institute of Technology 1993 - 1997
Publication Info
Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway. Cha JH, Choi YJ, Cha SH, Choi CH, Cho WH Oncol Rep. 28(1):41-8. doi: 10.3892/or.2012.1772. July 2012. View on PubMed.
Cytomegalovirus infection in patients with new onset ulcerative colitis: a prospective study. Kim YS, Kim YH, Kim JS, Cheon JH, Ye BD, Jung SA, Park YS and 5 others Hepatogastroenterology. 59(116):1098-101. doi: 10.5754/hge10217. June 2012. View on PubMed.
The Effect of Meditation on Brain Structure: Cortical Thickness Mapping and Diffusion Tensor Imaging. Kang DH, Jo HJ, Jung WH, Kim SH, Jung YH, Choi CH, Lee US, An SC, Jang JH, Kwon JS Soc Cogn Affect Neurosci. :. doi: 10.1093/scan/nss056. May 7, 2012. View on PubMed.
Sexual Function after Surgery for Early-Stage Cervical Cancer: Is There a Difference in It According to the Extent of Surgical Radicality? Song T, Choi CH, Lee YY, Kim TJ, Lee JW, Kim BG, Bae DS J Sex Med. :. doi: 10.1111/j.1743-6109.2012.02723.x. April 30, 2012. View on PubMed.
Functional outcomes and structural integrity after double-pulley suture bridge rotator cuff repair using serial ultrasonographic examination. Choi CH, Kim SK, Cho MR, Baek SH, Lee JK, Kim SS, Park CM J Shoulder Elbow Surg. :. doi: 10.1016/j.jse.2011.12.012. April 25, 2012. View on PubMed.
Total knee arthroplasty in rheumatoid arthritis. Lee JK, Choi CH Knee Surg Relat Res. 24(1):1-6. doi: 10.5792/ksrr.2012.24.1.1. March 2012. View on PubMed.
Effect of bamboo salt-NaF dentifrice on enamel remineralization. Choi CH, Ha MO, Youn HJ, Jeong SS, Iijima Y, Sohn W, Hong SJ Am J Dent. 25(1):9-12. February 2012. View on PubMed.
Ligament reconstruction in congenital absence of the anterior cruciate ligament: a case report. Lee JJ, Oh WT, Shin KY, Ko MS, Choi CH Knee Surg Relat Res. 23(4):240-3. doi: 10.5792/ksrr.2011.23.4.240. December 2011. View on PubMed.
Medial meniscal tears in anterior cruciate ligament-deficient knees: effects of posterior tibial slope on medial meniscal tear. Lee JJ, Choi YJ, Shin KY, Choi CH Knee Surg Relat Res. 23(4):227-30. doi: 10.5792/ksrr.2011.23.4.227. December 2011. View on PubMed.
The Pattern of Use of Oral NSAIDs with or without Co-prescription of Gastroprotective Agent for Arthritic Knee by Korean Practitioners. Kim HC, Lee MC, Moon YW, Seo SS, Lee KW, Lee JH, Choi CH Knee Surg Relat Res. 23(4):203-7. doi: 10.5792/ksrr.2011.23.4.203. December 2011. View on PubMed.
Profiling the thermodynamic softness of adenoviral promoters. Choi CH, Rapti Z, Gelev V, Hacker MR, Alexandrov B, Park EJ, Park JS and 5 others Biophys J. 95(2):597-608. doi: 10.1529/biophysj.107.123471. April 4, 2008. View on PubMed.
Genes invoked in the ovarian transition to menopause. Zimon A, Erat A, Von Wald T, Bissell B, Koulova A, Choi CH, Bachvarov D, Reindollar RH, Usheva A Nucleic Acids Res. 34(11):3279-87. doi: 10.1093/nar/gkl387. June 28, 2006. View on PubMed.
Healing length and bubble formation in DNA. Rapti Z, Smerzi A, Rasmussen KO, Bishop AR, Choi CH, Usheva A Phys Rev E Stat Nonlin Soft Matter Phys. 73(5 Pt 1):051902. doi: 10.1103/PhysRevE.73.051902. May 4, 2006. View on PubMed.
Metabolic stress regulates basic transcription through acetyl-coenzyme A. Choi CH, Zimon A, Usheva A Cell Mol Life Sci. 62(6):625-8. doi: 10.1007/s00018-005-4516-6. March 2005. View on PubMed.
Capacitance-derived dielectric constants demonstrate differential preinitiation complexes in TBP-independent and TBP-dependent transcription. Choi CH, Sabourin NA, Reagor DW, Redondo A, Usheva A Biophys Chem. 111(1):9-14. doi: 10.1016/j.bpc.2004.03.007. September 1, 2004. View on PubMed.
DNA dynamically directs its own transcription initiation. Choi CH, Kalosakas G, Rasmussen KO, Hiromura M, Bishop AR, Usheva A Nucleic Acids Res. 32(4):1584-90. doi: 10.1093/nar/gkh335. March 5, 2004. View on PubMed.
Auto-acetylation of transcription factors as a control mechanism in gene expression. Choi CH, Burton ZF, Usheva A Cell Cycle. 3(2):114-5. doi: 10.4161/cc.3.2.651. February 2004. View on PubMed.
Transcription factor IIB acetylates itself to regulate transcription. Choi CH, Hiromura M, Usheva A Nature. 424(6951):965-9. doi: 10.1038/nature01899. August 21, 2003. View on PubMed.
YY1 is regulated by O-linked N-acetylglucosaminylation (O-glcNAcylation). Hiromura M, Choi CH, Sabourin NA, Jones H, Bachvarov D, Usheva A J Biol Chem. 278(16):14046-52. doi: 10.1074/jbc.M300789200. April 18, 2003. View on PubMed.
YY1-DNA interaction results in a significant change of electronic context as measured by capacitance. Choi CH, Moser J, Sabourin NA, Blagoev K, Naughton M, Usheva A Biophys Chem. 103(2):109-15. January 21, 2003. View on PubMed.
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