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Juha Matilainen

Laboratory Director - Nordic Laboratories

Position - Company  
CEO - Woble Helsinki Oy Dec 2011 - Nov 2017
Laboratory Director - Nordic Laboratories Dec 2017 - Present
Degree - University  
Ph.D., Biochemistry - University of Eastern Finland 2007 - 2010
Publication Info
Detection and screening of chromosomal rearrangements in uterine leiomyomas by long-distance inverse PCR. Pradhan B, Sarvilinna N, Matilainen J, Aska E, Sjöberg J, Kauppi L Genes Chromosomes Cancer. 55(3):215-26. doi: 10.1002/gcc.22317. March 2016. View on PubMed.
Dynamic nature of transcriptional regulation of nuclear receptor target genes in the context of chromatin organization. Väisänen S, Matilainen J, Carlberg C Dermatoendocrinol. 3(3):125-9. doi: 10.4161/derm.3.3.15803. July 2011. View on PubMed.
Mechanism of 1α,25-dihydroxyvitamin D(3)-dependent repression of interleukin-12B. Gynther P, Toropainen S, Matilainen JM, Seuter S, Carlberg C, Väisänen S Biochim Biophys Acta. 1813(5):810-8. doi: 10.1016/j.bbamcr.2011.01.037. May 2011. View on PubMed.
Primary effect of 1α,25(OH)₂D₃ on IL-10 expression in monocytes is short-term down-regulation. Matilainen JM, Husso T, Toropainen S, Seuter S, Turunen MP, Gynther P, Ylä-Herttuala S, Carlberg C, Väisänen S Biochim Biophys Acta. 1803(11):1276-86. doi: 10.1016/j.bbamcr.2010.07.009. November 2010. View on PubMed.
The number of vitamin D receptor binding sites defines the different vitamin D responsiveness of the CYP24 gene in malignant and normal mammary cells. Matilainen JM, Malinen M, Turunen MM, Carlberg C, Väisänen S J Biol Chem. 285(31):24174-83. doi: 10.1074/jbc.M110.124073. July 30, 2010. View on PubMed.
The genes encoding cytokines IL-2, IL-10 and IL-12B are primary 1alpha,25(OH)2D3 target genes. Matilainen JM, Räsänen A, Gynther P, Väisänen S J Steroid Biochem Mol Biol. 121(1-2):142-5. doi: 10.1016/j.jsbmb.2010.03.020. July 2010. View on PubMed.
Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists. Poutiainen PK, Venäläinen TA, Peräkylä M, Matilainen JM, Väisänen S, Honkakoski P, Laatikainen R, Pulkkinen JT Bioorg Med Chem. 18(10):3437-47. doi: 10.1016/j.bmc.2010.04.007. May 15, 2010. View on PubMed.
From Fabio Bianco (Neuro-Zone srl) on 2016-12-01 06:24:29 -0500 Great professionalism! Read more
From Erez Sur (Ben-Gurion University of the Negev) on 2016-07-17 03:28:53 -0400 I'd like to thank Woble and Dr. Matilainen for their professional genotyping service, as well as ... Read more