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Viktor Szegedi

Assistant prof. - Biological Research Center - HAS

Position - Company  
Postdoc - Bay Zoltan Foundation for Applied Research - BAYGEN 2006 - 2012
Assistant prof. - Biological Research Center - HAS 2012 - Present
Degree - University  
Ph.D., Neuroscience - University of Szeged 2003 - 2006
Publication Info
GluA1 phosphorylation alters evoked firing pattern in vivo. Barkóczi B, Juhász G, Averkin RG, Vörös I, Vertes P, Penke B, Szegedi V Neural Plast. 2012:286215. doi: 10.1155/2012/286215. April 9, 2012. View on PubMed.
Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways. Szegedi V, Juhász G, Zhang X, Barkóczi B, Qi H, Madeira A, Kapus G, Svenningsson P, Spedding M, Penke B Neurochem Int. 59(8):1109-22. doi: 10.1016/j.neuint.2011.10.008. December 2011. View on PubMed.
Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation. Virok DP, Simon D, Bozsó Z, Rajkó R, Datki Z, Bálint É, Szegedi V, Janáky T, Penke B, Fülöp L J Proteome Res. 10(4):1538-47. doi: 10.1021/pr1009096. April 1, 2011. View on PubMed.
Functional changes in transcriptomes of the prefrontal cortex and hippocampus in a mouse model of anxiety. Virok DP, Kis Z, Szegedi V, Juhász G, Zvara A Jr, Müller G, Lévay G and 6 others Pharmacol Rep. 63(2):348-61. 2011. View on PubMed.
In vivo evidence for functional NMDA receptor blockade by memantine in rat hippocampal neurons. Szegedi V, Juhász G, Parsons CG, Budai D J Neural Transm. 117(10):1189-94. doi: 10.1007/s00702-010-0471-y. October 2010. View on PubMed.
Controlled in situ preparation of A beta(1-42) oligomers from the isopeptide "iso-A beta(1-42)", physicochemical and biological characterization. Bozso Z, Penke B, Simon D, Laczkó I, Juhász G, Szegedi V, Kasza A and 7 others Peptides. 31(2):248-56. doi: 10.1016/j.peptides.2009.12.001. February 2010. View on PubMed.
Fibrillar Abeta (1-42) enhances NMDA receptor sensitivity via the integrin signaling pathway. Uhász GJ, Barkóczi B, Vass G, Datki Z, Hunya A, Fülöp L, Budai D, Penke B, Szegedi V J Alzheimers Dis. 19(3):1055-67. doi: 10.3233/JAD-2009-1301. 2010. View on PubMed.
An intraperitoneally administered pentapeptide protects against Abeta (1-42) induced neuronal excitation in vivo. Juhász G, Márki A, Vass G, Fülöp L, Budai D, Penke B, Falkay G, Szegedi V J Alzheimers Dis. 16(1):189-96. doi: 10.3233/JAD-2009-0947. 2009. View on PubMed.
Integrin activation modulates NMDA and AMPA receptor function of CA1 cells in a dose-related fashion in vivo. Juhász G, Vass G, Bozsó Z, Budai D, Penke B, Szegedi V Brain Res. 1233:20-6. doi: 10.1016/j.brainres.2008.05.032. October 3, 2008. View on PubMed.
Differences between normal and alpha-synuclein overexpressing SH-SY5Y neuroblastoma cells after Abeta(1-42) and NAC treatment. Hunya A, Földi I, Szegedi V, Soós K, Zarándi M, Szabó A, Zádori D, Penke B, Datki ZL Brain Res Bull. 75(5):648-54. doi: 10.1016/j.brainresbull.2007.10.035. March 28, 2008. View on PubMed.
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo. Szegedi V, Juhász G, Rózsa E, Juhász-Vedres G, Datki Z, Fülöp L, Bozsó Z and 10 others FASEB J. 20(8):1191-3. doi: 10.1096/fj.05-4891fje. June 2006. View on PubMed.
Divergent effects of Abeta1-42 on ionotropic glutamate receptor-mediated responses in CA1 neurons in vivo. Szegedi V, Juhász G, Budai D, Penke B Brain Res. 1062(1-2):120-6. doi: 10.1016/j.brainres.2005.09.014. November 16, 2005. View on PubMed.
Transient alterations in neuronal and behavioral activity following bensultap and fipronil treatment in rats. Szegedi V, Bárdos G, Détári L, Tóth A, Banczerowski-Pelyhe I, Világi I Toxicology. 214(1-2):67-76. doi: 10.1016/j.tox.2005.05.023. October 15, 2005. View on PubMed.
Pentapeptides derived from Abeta 1-42 protect neurons from the modulatory effect of Abeta fibrils--an in vitro and in vivo electrophysiological study. Szegedi V, Fülöp L, Farkas T, Rózsa E, Robotka H, Kis Z, Penke Z and 8 others Neurobiol Dis. 18(3):499-508. doi: 10.1016/j.nbd.2004.12.008. April 2005. View on PubMed.
Enhancement of NMDA responses by beta-amyloid peptides in the hippocampus in vivo. Molnár Z, Soós K, Lengyel I, Penke B, Szegedi V, Budai D Neuroreport. 15(10):1649-52. July 19, 2004. View on PubMed.
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