Missing Avatar

Greg Fegan

Head of Statistics - KEMRI-Wellcome Trust Research Programme View Biosketch →

Position - Company  
Head of Statistics - KEMRI-Wellcome Trust Research Programme

Also hold an appointment at University of Oxford

Show details
Oct 2003 - Present
Degree - University  
Ph.D, Epidemiology - Tulane University School of Public Health and Tropical Medicine 1994 - 2003
Publication Info
Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children. Ndungu FM, Olotu A, Mwacharo J, Nyonda M, Apfeld J, Mramba LK, Fegan GW, Bejon P, Marsh K Proc Natl Acad Sci U S A. 109(21):8247-52. doi: 10.1073/pnas.1200472109. May 22, 2012. View on PubMed.
Prognostic indicators of life-threatening malaria are associated with distinct parasite variant antigen profiles. Warimwe GM, Fegan G, Musyoki JN, Newton CR, Opiyo M, Githinji G, Andisi C and 4 others Sci Transl Med. 4(129):129ra45. doi: 10.1126/scitranslmed.3003247. April 11, 2012. View on PubMed.
Estimating individual exposure to malaria using local prevalence of malaria infection in the field. Olotu A, Fegan G, Wambua J, Nyangweso G, Ogada E, Drakeley C, Marsh K, Bejon P PLoS One. 7(3):e32929. doi: 10.1371/journal.pone.0032929. March 29, 2012. View on PubMed.
Reliability and accuracy of anthropometry performed by community health workers among infants under 6 months in rural Kenya. Mwangome MK, Fegan G, Mbunya R, Prentice AM, Berkley JA Trop Med Int Health. :. doi: 10.1111/j.1365-3156.2012.02959.x. February 26, 2012. View on PubMed.
Continuous EEG monitoring in Kenyan children with non-traumatic coma. Gwer S, Idro R, Fegan G, Chengo E, Garrashi H, White S, Kirkham FJ, Newton CR Arch Dis Child. :. doi: 10.1136/archdischild-2011-300935. February 10, 2012. View on PubMed.
The microbiologic safety of umbilical cord blood transfusion for children with severe anemia in Mombasa, Kenya. Hassall OW, Thitiri J, Fegan G, Pole L, Mwarumba S, Denje D, Wambua K and 5 others Transfusion. :. doi: 10.1111/j.1537-2995.2011.03487.x. December 21, 2011. View on PubMed.
Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast. Borrmann S, Sasi P, Mwai L, Bashraheil M, Abdallah A, Muriithi S, Frühauf H and 16 others PLoS One. 6(11):e26005. doi: 10.1371/journal.pone.0026005. November 10, 2011. View on PubMed.
Are diagnostic criteria for acute malnutrition affected by hydration status in hospitalized children? A repeated measures study. Mwangome MK, Fegan G, Prentice AM, Berkley JA Nutr J. 10:92. doi: 10.1186/1475-2891-10-92. September 13, 2011. View on PubMed.
Mortality after fluid bolus in African children with severe infection. Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R and 12 others N Engl J Med. 364(26):2483-95. doi: 10.1056/NEJMoa1101549. June 30, 2011. View on PubMed.
Rapid improvement of depressive symptoms and cognition in an elderly patient with a single session of piano playing: A clinical treatment report. Manalai G, Manalai P, Dutta R, Fegan G, Scrofani P Aging Clin Exp Res. :. June 27, 2011. View on PubMed.
The impact of retail-sector delivery of artemether-lumefantrine on malaria treatment of children under five in Kenya: a cluster randomized controlled trial. Kangwana BP, Kedenge SV, Noor AM, Alegana VA, Nyandigisi AJ, Pandit J, Fegan GW and 4 others PLoS Med. 8(5):e1000437. doi: 10.1371/journal.pmed.1000437. May 31, 2011. View on PubMed.
A multifaceted intervention to implement guidelines and improve admission paediatric care in Kenyan district hospitals: a cluster randomised trial. Ayieko P, Ntoburi S, Wagai J, Opondo C, Opiyo N, Migiro S, Wamae A and 6 others PLoS Med. 8(4):e1001018. doi: 10.1371/journal.pmed.1001018. April 5, 2011. View on PubMed.
Mortality in sickle cell anemia in Africa: a prospective cohort study in Tanzania. Makani J, Cox SE, Soka D, Komba AN, Oruo J, Mwamtemi H, Magesa P and 13 others PLoS One. 6(2):e14699. doi: 10.1371/journal.pone.0014699. February 16, 2011. View on PubMed.
The potential of internet-based technologies for sharing data of public health importance. Fegan G, Moulsdale M, Todd J Bull World Health Organ. 89(2):82. doi: 10.2471/BLT.11.085910. February 1, 2011. View on PubMed.
Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia. Makani J, Menzel S, Nkya S, Cox SE, Drasar E, Soka D, Komba AN and 7 others Blood. 117(4):1390-2. doi: 10.1182/blood-2010-08-302703. January 27, 2011. View on PubMed.
Defining clinical malaria: the specificity and incidence of endpoints from active and passive surveillance of children in rural Kenya. Olotu A, Fegan G, Williams TN, Sasi P, Ogada E, Bauni E, Wambua J, Marsh K, Borrmann S, Bejon P PLoS One. 5(12):e15569. doi: 10.1371/journal.pone.0015569. December 16, 2010. View on PubMed.
Hypoglycaemia in severe malaria, clinical associations and relationship to quinine dosage. Ogetii GN, Akech S, Jemutai J, Boga M, Kivaya E, Fegan G, Maitland K BMC Infect Dis. 10:334. doi: 10.1186/1471-2334-10-334. November 22, 2010. View on PubMed.
Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis. Idro R, Gwer S, Williams TN, Otieno T, Uyoga S, Fegan G, Kager PA and 4 others PLoS One. 5(11):e14001. doi: 10.1371/journal.pone.0014001. November 16, 2010. View on PubMed.
Changing trends in blood transfusion in children and neonates admitted in Kilifi District Hospital, Kenya. Pedro R, Akech S, Fegan G, Maitland K Malar J. 9:307. doi: 10.1186/1475-2875-9-307. October 30, 2010. View on PubMed.
Phase II trial on the use of Dextran 70 or starch for supportive therapy in Kenyan children with severe malaria. Akech SO, Jemutai J, Timbwa M, Kivaya E, Boga M, Fegan G, Maitland K Crit Care Med. 38(8):1630-6. doi: 10.1097/CCM.0b013e3181e81165. August 2010. View on PubMed.
Further analysis of correlates of protection from a phase 2a trial of the falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults. Olotu AI, Fegan G, Bejon P J Infect Dis. 201(6):970-1. doi: 10.1086/651025. March 15, 2010. View on PubMed.
Allele-specific antibodies to Plasmodium falciparum merozoite surface protein-2 and protection against clinical malaria. Osier FH, Murungi LM, Fegan G, Tuju J, Tetteh KK, Bull PC, Conway DJ, Marsh K Parasite Immunol. 32(3):193-201. doi: 10.1111/j.1365-3024.2009.01178.x. March 2010. View on PubMed.
Evaluating different dimensions of programme effectiveness for private medicine retailer malaria control interventions in Kenya. Abuya TO, Fegan G, Amin AA, Akhwale WS, Noor AM, Snow RW, Marsh V PLoS One. 5(1):e8937. doi: 10.1371/journal.pone.0008937. January 28, 2010. View on PubMed.
Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization. Makani J, Komba AN, Cox SE, Oruo J, Mwamtemi K, Kitundu J, Magesa P and 10 others Blood. 115(2):215-20. doi: 10.1182/blood-2009-07-233528. January 14, 2010. View on PubMed.
Plasmodium falciparum var gene expression is modified by host immunity. Warimwe GM, Keane TM, Fegan G, Musyoki JN, Newton CR, Pain A, Berriman M, Marsh K, Bull PC Proc Natl Acad Sci U S A. 106(51):21801-6. doi: 10.1073/pnas.0907590106. December 22, 2009. View on PubMed.
The level and duration of RSV-specific maternal IgG in infants in Kilifi Kenya. Ochola R, Sande C, Fegan G, Scott PD, Medley GF, Cane PA, Nokes DJ PLoS One. 4(12):e8088. doi: 10.1371/journal.pone.0008088. December 2, 2009. View on PubMed.
Impaired everyday memory associated with encephalopathy of severe malaria: the role of seizures and hippocampal damage. Kihara M, Carter JA, Holding PA, Vargha-Khadem F, Scott RC, Idro R, Fegan GW, de Haan M, Neville BG, Newton CR Malar J. 8:273. doi: 10.1186/1475-2875-8-273. December 1, 2009. View on PubMed.
The quality of stored umbilical cord and adult-donated whole blood in Mombasa, Kenya. Hassall O, Maitland K, Fegan G, Thitiri J, Pole L, Mwakesi R, Denje D, Wambua K, Mandaliya K, Bates I Transfusion. 50(3):611-6. doi: 10.1111/j.1537-2995.2009.02489.x. November 13, 2009. View on PubMed.
Transmission-dependent tolerance to multiclonal Plasmodium falciparum infection. Färnert A, Williams TN, Mwangi TW, Ehlin A, Fegan G, Macharia A, Lowe BS, Montgomery SM, Marsh K J Infect Dis. 200(7):1166-75. doi: 10.1086/605652. October 1, 2009. View on PubMed.
HIV infection, malnutrition, and invasive bacterial infection among children with severe malaria. Berkley JA, Bejon P, Mwangi T, Gwer S, Maitland K, Williams TN, Mohammed S and 8 others Clin Infect Dis. 49(3):336-43. doi: 10.1086/600299. August 1, 2009. View on PubMed.
Impact of ministry of health interventions on private medicine retailer knowledge and practices on anti-malarial treatment in Kenya. Abuya T, Fegan G, Rowa Y, Karisa B, Ochola S, Mutemi W, Marsh V Am J Trop Med Hyg. 80(6):905-13. June 2009. View on PubMed.
Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness. Makani J, Kirkham FJ, Komba A, Ajala-Agbo T, Otieno G, Fegan G, Williams TN, Marsh K, Newton CR Br J Haematol. 145(4):529-32. doi: 10.1111/j.1365-2141.2009.07660.x. March 27, 2009. View on PubMed.
Examining agreement between clinicians when assessing sick children. Wagai J, Senga J, Fegan G, English M PLoS One. 4(2):e4626. doi: 10.1371/journal.pone.0004626. February 27, 2009. View on PubMed.
Health systems research in a low-income country: easier said than done. English M, Irimu G, Wamae A, Were F, Wasunna A, Fegan G, Peshu N Arch Dis Child. 93(6):540-4. doi: 10.1136/adc.2007.126466. June 2008. View on PubMed.
Evidence for over-dispersion in the distribution of clinical malaria episodes in children. Mwangi TW, Fegan G, Williams TN, Kinyanjui SM, Snow RW, Marsh K PLoS One. 3(5):e2196. doi: 10.1371/journal.pone.0002196. May 21, 2008. View on PubMed.
The use of mosquito nets and the prevalence of Plasmodium falciparum infection in rural South Central Somalia. Noor AM, Moloney G, Borle M, Fegan GW, Shewchuk T, Snow RW PLoS One. 3(5):e2081. doi: 10.1371/journal.pone.0002081. May 7, 2008. View on PubMed.
Longitudinal analyses of immune responses to Plasmodium falciparum derived peptides corresponding to novel blood stage antigens in coastal Kenya. Agak GW, Bejon P, Fegan G, Gicheru N, Villard V, Kajava AV, Marsh K, Corradin G Vaccine. 26(16):1963-71. doi: 10.1016/j.vaccine.2008.02.020. April 7, 2008. View on PubMed.
Could an open-source clinical trial data-management system be what we have all been looking for? Fegan GW, Lang TA PLoS Med. 5(3):e6. doi: 10.1371/journal.pmed.0050006. March 4, 2008. View on PubMed.
Breadth and magnitude of antibody responses to multiple Plasmodium falciparum merozoite antigens are associated with protection from clinical malaria. Osier FH, Fegan G, Polley SD, Murungi L, Verra F, Tetteh KK, Lowe B and 9 others Infect Immun. 76(5):2240-8. doi: 10.1128/IAI.01585-07. March 3, 2008. View on PubMed.
Effect of newborn resuscitation training on health worker practices in Pumwani Hospital, Kenya. Opiyo N, Were F, Govedi F, Fegan G, Wasunna A, English M PLoS One. 3(2):e1599. doi: 10.1371/journal.pone.0001599. February 13, 2008. View on PubMed.
Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria. Verra F, Simpore J, Warimwe GM, Tetteh KK, Howard T, Osier FH, Bancone G and 8 others PLoS One. 2(10):e978. doi: 10.1371/journal.pone.0000978. October 3, 2007. View on PubMed.
Effect of expanded insecticide-treated bednet coverage on child survival in rural Kenya: a longitudinal study. Fegan GW, Noor AM, Akhwale WS, Cousens S, Snow RW Lancet. 370(9592):1035-9. doi: 10.1016/S0140-6736(07)61477-9. September 22, 2007. View on PubMed.
Extended follow-up following a phase 2b randomized trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya. Bejon P, Ogada E, Mwangi T, Milligan P, Lang T, Fegan G, Gilbert SC, Peshu N, Marsh K, Hill AV PLoS One. 2(8):e707. doi: 10.1371/journal.pone.0000707. August 15, 2007. View on PubMed.
Burden, features, and outcome of neurological involvement in acute falciparum malaria in Kenyan children. Idro R, Ndiritu M, Ogutu B, Mithwani S, Maitland K, Berkley J, Crawley J and 6 others JAMA. 297(20):2232-40. doi: 10.1001/jama.297.20.2232. May 23, 2007. View on PubMed.
Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions. Abuya TO, Mutemi W, Karisa B, Ochola SA, Fegan G, Marsh V Malar J. 6:57. doi: 10.1186/1475-2875-6-57. May 10, 2007. View on PubMed.
Phase III trials required to resolve clinical equipoise over optimal fluid management in children with severe malaria. Maitland K, Akech S, Gwer S, Idro R, Fegan G, Eziefula AC, Levin M, Newton CR PLoS Clin Trials. 2(2):e2. doi: 10.1371/journal.pctr.0020002. February 9, 2007. View on PubMed.
A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya. Bejon P, Mwacharo J, Kai O, Mwangi T, Milligan P, Todryk S, Keating S and 9 others PLoS Clin Trials. 1(6):e29. doi: 10.1371/journal.pctr.0010029. October 20, 2006. View on PubMed.
Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial. Akech S, Gwer S, Idro R, Fegan G, Eziefula AC, Newton CR, Levin M, Maitland K PLoS Clin Trials. 1(5):e21. doi: 10.1371/journal.pctr.0010021. September 15, 2006. View on PubMed.
Immunization coverage and risk factors for failure to immunize within the Expanded Programme on Immunization in Kenya after introduction of new Haemophilus influenzae type b and hepatitis b virus antigens. Ndiritu M, Cowgill KD, Ismail A, Chiphatsi S, Kamau T, Fegan G, Feikin DR, Newton CR, Scott JA BMC Public Health. 6:132. doi: 10.1186/1471-2458-6-132. May 17, 2006. View on PubMed.
Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria. Idro R, Otieno G, White S, Kahindi A, Fegan G, Ogutu B, Mithwani S, Maitland K, Neville BG, Newton CR Malar J. 4:57. doi: 10.1186/1475-2875-4-57. December 7, 2005. View on PubMed.
Risk factors for persisting neurological and cognitive impairments following cerebral malaria. Idro R, Carter JA, Fegan G, Neville BG, Newton CR Arch Dis Child. 91(2):142-8. doi: 10.1136/adc.2005.077784. December 2, 2005. View on PubMed.
Perturbations in electrolyte levels in kenyan children with severe malaria complicated by acidosis. Maitland K, Pamba A, Fegan G, Njuguna P, Nadel S, Newton CR, Lowe B Clin Infect Dis. 40(1):9-16. doi: 10.1086/426022. January 1, 2005. View on PubMed.
The platelet glycoprotein Ia/IIa gene polymorphism C807T/G873A: a novel risk factor for retinal vein occlusion. Dodson PM, Haynes J, Starczynski J, Farmer J, Shigdar S, Fegan G, Johnson RJ, Fegan C Eye (Lond). 17(6):772-7. doi: 10.1038/sj.eye.6700452. August 2003. View on PubMed.
Data management for an efficacy trial of a vaccine in the Gambia. Lahai GP, Mulholland EK, Hilton S, Fegan G, Inskip H, Yuuni O, Bangali JE, Greenwood BM Methods Inf Med. 36(3):214-20. August 1997. View on PubMed.
Implementing a nationwide insecticide-impregnated bednet programme in The Gambia. Cham MK, D'Alessandro U, Todd J, Bennett S, Fegan G, Cham BA, Greenwood BM Health Policy Plan. 11(3):292-8. September 1996. View on PubMed.
Efficacy trial of malaria vaccine SPf66 in Gambian infants. D'Alessandro U, Leach A, Drakeley CJ, Bennett S, Olaleye BO, Fegan GW, Jawara M, Langerock P, George MO, Targett GA Lancet. 346(8973):462-7. August 19, 1995. View on PubMed.
A pilot safety and immunogenicity study of the malaria vaccine SPf66 in Gambian infants. Leach A, Drakeley CJ, D'Alessandro U, Fegan GW, Bennett S, Ballou WR, Targett GA, Greenwood BM Parasite Immunol. 17(8):441-4. August 1995. View on PubMed.
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 6. The impact of the interventions on mortality and morbidity from malaria. Alonso PL, Lindsay SW, Armstrong Schellenberg JR, Keita K, Gomez P, Shenton FC, Hill AG, David PH, Fegan G, Cham K Trans R Soc Trop Med Hyg. 87 Suppl 2:37-44. June 1993. View on PubMed.
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 2. Mortality and morbidity from malaria in the study area. Alonso PL, Lindsay SW, Armstrong Schellenberg JR, Gomez P, Hill AG, David PH, Fegan G, Cham K, Greenwood BM Trans R Soc Trop Med Hyg. 87 Suppl 2:13-7. June 1993. View on PubMed.
Socioeconomic inequalities in childhood mortality: the 1970s to the 1980s. Cleland J, Bicego G, Fegan G Health Transit Rev. 2(1):1-18. April 1992. View on PubMed.
The effect of insecticide-treated bed nets on mortality of Gambian children. Alonso PL, Lindsay SW, Armstrong JR, Conteh M, Hill AG, David PH, Fegan G, de Francisco A, Hall AJ, Shenton FC Lancet. 337(8756):1499-502. June 22, 1991. View on PubMed.
  • Greg Fegan hasn't received any ratings yet...