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Mark Cobbold

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Degree - University  
MB ChB, Medicine - University of Edinburgh 1989 - 1995
Publication Info
Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay. Whitelegg AM, Birtwistle J, Richter A, Campbell JP, Turner JE, Ahmed TM, Giles LJ and 6 others J Immunol Methods. 377(1-2):37-46. doi: 10.1016/j.jim.2012.01.007. March 30, 2012. View on PubMed.
Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions. Khan N, Cobbold M, Cummerson J, Moss PA Immunology. 131(4):537-48. doi: 10.1111/j.1365-2567.2010.03326.x. August 16, 2010. View on PubMed.
Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults. MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA and 15 others Science. 328(5977):508-12. doi: 10.1126/science.1180346. April 23, 2010. View on PubMed.
Adenovirus vector-specific T cells demonstrate a unique memory phenotype with high proliferative potential and coexpression of CCR5 and integrin alpha4beta7. Chakupurakal G, Onion D, Cobbold M, Mautner V, Moss PA AIDS. 24(2):205-10. doi: 10.1097/QAD.0b013e328333addf. January 16, 2010. View on PubMed.
Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition. Nicholls S, Piper KP, Mohammed F, Dafforn TR, Tenzer S, Salim M, Mahendra P and 7 others Proc Natl Acad Sci U S A. 106(10):3889-94. doi: 10.1073/pnas.0900411106. March 10, 2009. View on PubMed.
Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Mohammed F, Cobbold M, Zarling AL, Salim M, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Engelhard VH, Willcox BE Nat Immunol. 9(11):1236-43. doi: 10.1038/ni.1660. October 5, 2008. View on PubMed.
Synthesis and ex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes. Jones MA, Notta JK, Cobbold M, Palendira M, Hislop AD, Wilkie J, Snaith JS J Pept Sci. 14(3):313-20. doi: 10.1002/psc.930. March 2008. View on PubMed.
Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E and 12 others Blood. 108(6):1797-808. doi: 10.1182/blood-2006-02-001909. September 15, 2006. View on PubMed.
Power output and muscle myosin heavy chain composition in young and elderly men. Pearson SJ, Cobbold M, Orrell RW, Harridge SD Med Sci Sports Exerc. 38(9):1601-7. doi: 10.1249/01.mss.0000227638.75983.9d. September 2006. View on PubMed.
In treatment-naïve and antiretroviral-treated subjects with HIV, reduced plasma adiponectin is associated with a reduced fractional clearance rate of VLDL, IDL and LDL apolipoprotein B-100. Das S, Shahmanesh M, Stolinski M, Shojaee-Moradie F, Jefferson W, Jackson NC, Cobbold M, Nightingale P, Umpleby AM Diabetologia. 49(3):538-42. doi: 10.1007/s00125-005-0085-3. January 24, 2006. View on PubMed.
Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers. Cobbold M, Khan N, Pourgheysari B, Tauro S, McDonald D, Osman H, Assenmacher M and 9 others J Exp Med. 202(3):379-86. doi: 10.1084/jem.20040613. August 1, 2005. View on PubMed.
Selection of CMV-specific CD8+ and CD4+ T cells by mini-EBV-transformed B cell lines. Wiesner M, Zentz C, Hammer MH, Cobbold M, Kern F, Kolb HJ, Hammerschmidt W, Zeidler R, Moosmann A Eur J Immunol. 35(7):2110-21. doi: 10.1002/eji.200425936. July 2005. View on PubMed.
Identification of cytomegalovirus-specific cytotoxic T lymphocytes in vitro is greatly enhanced by the use of recombinant virus lacking the US2 to US11 region or modified vaccinia virus Ankara expressing individual viral genes. Khan N, Bruton R, Taylor GS, Cobbold M, Jones TR, Rickinson AB, Moss PA J Virol. 79(5):2869-79. doi: 10.1128/JVI.79.5.2869-2879.2005. March 2005. View on PubMed.
Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. Khan N, Hislop A, Gudgeon N, Cobbold M, Khanna R, Nayak L, Rickinson AB, Moss PA J Immunol. 173(12):7481-9. December 15, 2004. View on PubMed.
The cellular immunotherapy of viral infection. Moss PA, Cobbold M, Craddock C Transfus Med. 13(6):405-15. December 2003. View on PubMed.
B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells. Moosmann A, Khan N, Cobbold M, Zentz C, Delecluse HJ, Hollweck G, Hislop AD and 7 others Blood. 100(5):1755-64. September 1, 2002. View on PubMed.
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. Khan N, Shariff N, Cobbold M, Bruton R, Ainsworth JA, Sinclair AJ, Nayak L, Moss PA J Immunol. 169(4):1984-92. August 15, 2002. View on PubMed.
Comparative analysis of CD8+ T cell responses against human cytomegalovirus proteins pp65 and immediate early 1 shows similarities in precursor frequency, oligoclonality, and phenotype. Khan N, Cobbold M, Keenan R, Moss PA J Infect Dis. 185(8):1025-34. doi: 10.1086/339963. April 15, 2002. View on PubMed.
Survival after bone-marrow transplantation. Cwynarski K, Craddock C, Cobbold M, Apperley J, Goldman J Lancet. 359(9309):887-8. doi: 10.1016/S0140-6736(02)07924-2. March 9, 2002. View on PubMed.
Purification of cytomegalovirus-specific CD8 T cells from peripheral blood using HLA-peptide tetramers. Keenan RD, Ainsworth J, Khan N, Bruton R, Cobbold M, Assenmacher M, Milligan DW, Moss PA Br J Haematol. 115(2):428-34. November 2001. View on PubMed.
Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation. Cwynarski K, Ainsworth J, Cobbold M, Wagner S, Mahendra P, Apperley J, Goldman J, Craddock C, Moss PA Blood. 97(5):1232-40. March 1, 2001. View on PubMed.
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