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Saibal Chakraborty

Research assistant and doctoral candidate - Dr Ramachandra S Hosmane's laboratory for drug design and synthesis View Biosketch →

Position - Company  
Research assistant and doctoral candidate - Dr Ramachandra S Hosmane's laboratory for drug design and synthesis University of Maryland Baltimore County

It is Medicinal Chemistry laboratory where I am engaged in designing and synthesizing transition state analog inhibitors of the enzyme Guanine deaminase (GDA) and do the biochemical testing (enzyme kinetics).

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Aug 2006 - Present
Degree - University  
Masters of Science, Chemistry - Indian Institute of Technology 2004 - 2006
Ph.D., Medicinal Chemistry - University of Maryland Baltimore County 2006 - Present
Publication Info
A CRITICAL STUDY ON THE INTERACTIONS OF HESPERITIN WITH HUMAN HEMOGLOBIN: FLUORESCENCE SPECTROSCOPIC AND MOLECULAR MODELING APPROACH. Chakraborty S, Chaudhuri S, Pahari B, Taylor J, Sengupta PK, Sengupta B J Lumin. 132(6):1522-1528. doi: 10.1016/j.jlumin.2012.01.021. June 2012. View on PubMed.
Pincer-Ligated Nickel Hydridoborate Complexes: the Dormant Species in Catalytic Reduction of Carbon Dioxide with Boranes. Chakraborty S, Zhang J, Patel YJ, Krause JA, Guan H Inorg Chem. :. doi: 10.1021/ic300587b. May 16, 2012. View on PubMed.
Altered manganese homeostasis: Implications for BLI-3-dependent dopaminergic neurodegeneration and SKN-1 protection in C. elegans. Chakraborty S, Aschner M J Trace Elem Med Biol. :. doi: 10.1016/j.jtemb.2012.03.011. May 14, 2012. View on PubMed.
Mechanistic Insight into the Structure and Dynamics of Entangled and Hydrated λ-Phage DNA. Chakraborty S, Uematsu T, Svanberg C, Jacobsson P, Swenson J, Zäch M, Trehan R, Armstrong G, Sengupta B J Phys Chem A. 116(17):4274-84. doi: 10.1021/jp2108363. May 3, 2012. View on PubMed.
Comparison of breast carcinoma prognostic/predictive biomarkers on cell blocks obtained by various methods: cellient, formalin and thrombin. Gorman BK, Kosarac O, Chakraborty S, Schwartz MR, Mody DR Acta Cytol. 56(3):289-96. doi: 10.1159/000337436. April 26, 2012. View on PubMed.
Preparation and in vitro-in vivo evaluation of aceclofenac loaded alginate microspheres: An investigation of effects of polymer using multiple comparison analysis. Khandai M, Chakraborty S, Nayak P, Krishna NB, Chakravarthi G, Acharjya B, Ghosh AK Curr Drug Deliv. :. April 20, 2012. View on PubMed.
Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans. Caito S, Fretham S, Martinez-Finley E, Chakraborty S, Avila D, Chen P, Aschner M Front Genet. 3:52. doi: 10.3389/fgene.2012.00052. April 10, 2012. View on PubMed.
Tarlov cysts: a report of two cases. Sen RK, Goyal T, Tripathy SK, Chakraborty S J Orthop Surg (Hong Kong). 20(1):87-9. doi: 10.1177/230949901202000117. April 2012. View on PubMed.
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancer. Chakraborty S, Kaur S, Guha S, Batra SK Biochim Biophys Acta. 1826(1):129-169. doi: 10.1016/j.bbcan.2012.03.008. March 31, 2012. View on PubMed.
Mathematical modeling of drug release profiles for modified hydrophobic HPMC based gels. Ghosal K, Chandra A, Rajabalaya R, Chakraborty S, Nanda A Pharmazie. 67(2):147-55. February 2012. View on PubMed.
A novel transition state analog inhibitor of guanase based on azepinomycin ring structure: Synthesis and biochemical assessment of enzyme inhibition. Chakraborty S, Shah NH, Fishbein JC, Hosmane RS Bioorg Med Chem Lett. 21(2):756-9. doi: 10.1016/j.bmcl.2010.11.109. January 15, 2011. View on PubMed.
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