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Mu Wang

Director - Mayo Clinic Proteomics Core
Rochester Minnesota, US

Position - Company  
Director - Mayo Clinic Proteomics Core Mayo Clinic Oct 2001 - Present
Degree - University  
Ph.D., Bio-Organic Chemistry - Washington University 1993 - 1998
Publication Info
Dual-source dual-power electrospinning and characteristics of multifunctional scaffolds for bone tissue engineering. Wang C, Wang M J Mater Sci Mater Med. :. doi: 10.1007/s10856-012-4669-4. May 17, 2012. View on PubMed.
The Beta2-Adrenergic Receptor is a Potential Prognostic Biomarker for Human Hepatocellular Carcinoma After Curative Resection. Chen D, Xing W, Hong J, Wang M, Huang Y, Zhu C, Yuan Y, Zeng W Ann Surg Oncol. :. doi: 10.1245/s10434-012-2396-1. May 17, 2012. View on PubMed.
A functional polymorphism C-1310G in the promoter region of Ku70/XRCC6 is associated with risk of renal cell carcinoma. Wang W, Pan X, Huo X, Yan F, Wang M, Wang D, Gao Y and 5 others Mol Carcinog. :. doi: 10.1002/mc.21914. May 16, 2012. View on PubMed.
Intravenous Renal Cell Transplantation (IRCT) for rats with acute and chronic renal failure. Kelly KJ, Zhang J, Wang M, Zhang S, Dominguez JH Am J Physiol Renal Physiol. :. doi: 10.1152/ajprenal.00680.2011. May 16, 2012. View on PubMed.
Computational identification of microRNAs in anatid herpesvirus 1 genome. Xiang J, Cheng A, Wang M, Zhang S, Zhu D, Jia R, Chen S, Zhou Y, Wang X, Chen X Virol J. 9(1):93. doi: 10.1186/1743-422X-9-93. May 14, 2012. View on PubMed.
3DMolNavi: A web-based retrieval and navigation tool for flexible molecular shape comparison. Liu YS, Wang M, Paul JC, Ramani K BMC Bioinformatics. 13(1):95. doi: 10.1186/1471-2105-13-95. May 14, 2012. View on PubMed.
Medium optimization and potential hepatoprotective effect of mycelial polysaccharides from Pholiota dinghuensis Bi against carbon tetrachloride-induced acute liver injury in mice. Gan D, Ma L, Jiang C, Wang M, Zeng X Food Chem Toxicol. :. doi: 10.1016/j.fct.2012.05.003. May 11, 2012. View on PubMed.
[Investigation of enterotoxin gene in clinical isolates of Staphylococcus aureus]. Cao H, Wang M, Zheng R, Li XP, Wang F, Jiang YS, Yang YF Nan Fang Yi Ke Da Xue Xue Bao. 32(5):738-41. May 2012. View on PubMed.
Host-microbe interactions in the neonatal intestine: role of human milk oligosaccharides. Donovan SM, Wang M, Li M, Friedberg I, Schwartz SL, Chapkin RS Adv Nutr. 3(3):450S-5S. doi: 10.3945/an.112.001859. May 1, 2012. View on PubMed.
[Effect of gradually induced disordered occlusion on the expression of osteoprotegerin and receptor activator of nuclear factor-kappaB ligand in mandibular condylar cartilage of rats]. Liu L, Xiong L, Sun L, He JJ, Wang M Hua Xi Kou Qiang Yi Xue Za Zhi. 30(2):119-22, 127. April 2012. View on PubMed.
Classification of HCV NS5B Polymerase Inhibitors Using Support Vector Machine. Wang M, Wang K, Yan A, Yu C Int J Mol Sci. 13(4):4033-47. doi: 10.3390/ijms13044033. March 27, 2012. View on PubMed.
The proteome of normal pancreatic juice. Doyle CJ, Yancey K, Pitt HA, Wang M, Bemis K, Yip-Schneider MT, Sherman ST, Lillemoe KD, Goggins MD, Schmidt CM Pancreas. 41(2):186-94. doi: 10.1097/MPA.0b013e31822862f6. March 2012. View on PubMed.
Biological macro-idea and criterion of osteopathic fracture immobilization in China's traditional Mongolian medicine. Zhao N, Wang M, Li XE J Tradit Chin Med. 32(1):114-8. March 2012. View on PubMed.
[Effects of organic fertilizer application rate on leaf photosynthetic characteristics and grain yield of dryland maize]. Wang XJ, Jia ZK, Liang LY, Ding RX, Wang M, Li H Ying Yong Sheng Tai Xue Bao. 23(2):419-25. February 2012. View on PubMed.
Mass spectrometry for protein quantification in biomarker discovery. Wang M, You J Methods Mol Biol. 815:199-225. doi: 10.1007/978-1-61779-424-7_16. 2012. View on PubMed.
Proteomic analysis of endothelial cold-adaptation. Zieger MA, Gupta MP, Wang M BMC Genomics. 12:630. doi: 10.1186/1471-2164-12-630. December 22, 2011. View on PubMed.
Proteomic Characterization of Cerebrospinal Fluid from Ataxia-Telangiectasia (A-T) Patients Using a LC/MS-Based Label-Free Protein Quantification Technology. Dzieciatkowska M, Qi G, You J, Bemis KG, Sahm H, Lederman HM, Crawford TO, Gelbert LM, Rothblum-Oviatt C, Wang M Int J Proteomics. 2011:578903. doi: 10.1155/2011/578903. June 23, 2011. View on PubMed.
Utility of formalin-fixed, paraffin-embedded liver biopsy specimens for global proteomic analysis in nonalcoholic steatohepatitis. Bell LN, Saxena R, Mattar SG, You J, Wang M, Chalasani N Proteomics Clin Appl. 5(7-8):397-404. doi: 10.1002/prca.201000144. June 8, 2011. View on PubMed.
Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes. Shao CH, Capek HL, Patel KP, Wang M, Tang K, DeSouza C, Nagai R, Mayhan W, Periasamy M, Bidasee KR Diabetes. 60(3):947-59. doi: 10.2337/db10-1145. February 7, 2011. View on PubMed.
Personalized medicine in oncology: tailoring the right drug to the right patient. Jiang Y, Wang M Biomark Med. 4(4):523-33. doi: 10.2217/bmm.10.66. August 2010. View on PubMed.
Carbonylation of myosin heavy chains in rat heart during diabetes. Shao CH, Rozanski GJ, Nagai R, Stockdale FE, Patel KP, Wang M, Singh J, Mayhan WG, Bidasee KR Biochem Pharmacol. 80(2):205-17. doi: 10.1016/j.bcp.2010.03.024. July 15, 2010. View on PubMed.
Knock-down of superoxide dismutase 1 sensitizes cisplatin-resistant human ovarian cancer cells. Kim JW, Sahm H, You J, Wang M Anticancer Res. 30(7):2577-81. July 2010. View on PubMed.
Multi-dimensional liquid chromatography in proteomics--a review. Zhang X, Fang A, Riley CP, Wang M, Regnier FE, Buck C Anal Chim Acta. 664(2):101-13. doi: 10.1016/j.aca.2010.02.001. April 7, 2010. View on PubMed.
Targeted quantitative analysis of superoxide dismutase 1 in cisplatin-sensitive and cisplatin-resistant human ovarian cancer cells. Kim JW, Nie B, Sahm H, Brown DP, Tegeler T, You JS, Wang M J Chromatogr B Analyt Technol Biomed Life Sci. 878(7-8):700-4. doi: 10.1016/j.jchromb.2010.01.013. March 1, 2010. View on PubMed.
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Bell LN, Lee L, Saxena R, Bemis KG, Wang M, Theodorakis JL, Vuppalanchi R, Alloosh M, Sturek M, Chalasani N Am J Physiol Gastrointest Liver Physiol. 298(5):G746-54. doi: 10.1152/ajpgi.00485.2009. February 18, 2010. View on PubMed.
Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry. Tabb DL, Vega-Montoto L, Rudnick PA, Variyath AM, Ham AJ, Bunk DM, Kilpatrick LE and 25 others J Proteome Res. 9(2):761-76. doi: 10.1021/pr9006365. February 5, 2010. View on PubMed.
Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease. Bell LN, Theodorakis JL, Vuppalanchi R, Saxena R, Bemis KG, Wang M, Chalasani N Hepatology. 51(1):111-20. doi: 10.1002/hep.23271. January 2010. View on PubMed.
Proteomic analysis of human aqueous humor using multidimensional protein identification technology. Richardson MR, Price MO, Price FW, Pardo JC, Grandin JC, You J, Wang M, Yoder MC Mol Vis. 15:2740-50. December 11, 2009. View on PubMed.
Proteomic analysis of blastema formation in regenerating axolotl limbs. Rao N, Jhamb D, Milner DJ, Li B, Song F, Wang M, Voss SR and 6 others BMC Biol. 7:83. doi: 10.1186/1741-7007-7-83. November 30, 2009. View on PubMed.
Intrinsic subtype-associated changes in the plasma proteome in breast cancer. Nakshatri H, Qi G, You J, Kerry B, Schneider B, Zon R, Buck C, Regnier F, Wang M Proteomics Clin Appl. 3(11):1305-13. doi: 10.1002/prca.200900040. November 2009. View on PubMed.
Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance. Paulovich AG, Billheimer D, Ham AJ, Vega-Montoto L, Rudnick PA, Tabb DL, Wang P and 23 others Mol Cell Proteomics. 9(2):242-54. doi: 10.1074/mcp.M900222-MCP200. October 26, 2009. View on PubMed.
Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses. Rudnick PA, Clauser KR, Kilpatrick LE, Tchekhovskoi DV, Neta P, Blonder N, Billheimer DD and 27 others Mol Cell Proteomics. 9(2):225-41. doi: 10.1074/mcp.M900223-MCP200. October 16, 2009. View on PubMed.
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Addona TA, Abbatiello SE, Schilling B, Skates SJ, Mani DR, Bunk DM, Spiegelman CH and 42 others Nat Biotechnol. 27(7):633-41. doi: 10.1038/nbt.1546. June 28, 2009. View on PubMed.
LC/MS-based quantitative proteomic analysis of paraffin-embedded archival melanomas reveals potential proteomic biomarkers associated with metastasis. Huang SK, Darfler MM, Nicholl MB, You J, Bemis KG, Tegeler TJ, Wang M and 5 others PLoS One. 4(2):e4430. doi: 10.1371/journal.pone.0004430. February 16, 2009. View on PubMed.
Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study. McBride WJ, Schultz JA, Kimpel MW, McClintick JN, Wang M, You J, Rodd ZA Pharmacol Biochem Behav. 92(2):304-13. doi: 10.1016/j.pbb.2008.12.019. January 6, 2009. View on PubMed.
Targeting superoxide dismutase 1 to overcome cisplatin resistance in human ovarian cancer. Brown DP, Chin-Sinex H, Nie B, Mendonca MS, Wang M Cancer Chemother Pharmacol. 63(4):723-30. doi: 10.1007/s00280-008-0791-x. July 12, 2008. View on PubMed.
Label-free mass spectrometry-based protein quantification technologies in proteomic analysis. Wang M, You J, Bemis KG, Tegeler TJ, Brown DP Brief Funct Genomic Proteomic. 7(5):329-39. doi: 10.1093/bfgp/eln031. June 25, 2008. View on PubMed.
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme. Janecki DJ, Bemis KG, Tegeler TJ, Sanghani PC, Zhai L, Hurley TD, Bosron WF, Wang M Anal Biochem. 369(1):18-26. doi: 10.1016/j.ab.2007.06.043. October 1, 2007. View on PubMed.
Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections. Li X, Wang S, Qi J, Echtenkamp SF, Chatterjee R, Wang M, Boons GJ, Dziarski R, Gupta D Immunity. 27(3):518-29. doi: 10.1016/j.immuni.2007.07.020. September 2007. View on PubMed.
A systems biology approach to the study of cisplatin drug resistance in ovarian cancers. Chen JY, Yan Z, Shen C, Fitzpatrick DP, Wang M J Bioinform Comput Biol. 5(2a):383-405. April 2007. View on PubMed.
CSK controls retinoic acid receptor (RAR) signaling: a RAR-c-SRC signaling axis is required for neuritogenic differentiation. Dey N, De PK, Wang M, Zhang H, Dobrota EA, Robertson KA, Durden DL Mol Cell Biol. 27(11):4179-97. doi: 10.1128/MCB.01352-06. February 26, 2007. View on PubMed.
Searching for potential biomarkers of cisplatin resistance in human ovarian cancer using a label-free LC/MS-based protein quantification method. Fitzpatrick DP, You JS, Bemis KG, Wery JP, Ludwig JR, Wang M Proteomics Clin Appl. 1(3):246-63. doi: 10.1002/prca.200600768. January 22, 2007. View on PubMed.
A comparative proteomic study to characterize the vinblastine resistance in human ovarian cancer cells. Brown DP, Gökmen-Polar Y, Jiang L, Tan J, Ringham H, Janecki DJ, Qi G, Witzmann FA, Sledge GW Jr, Wang M Proteomics Clin Appl. 1(1):18-31. doi: 10.1002/prca.200600171. December 5, 2006. View on PubMed.
Direct detection of glycogenin reaction products during glycogen initiation. Hurley TD, Walls C, Bennett JR, Roach PJ, Wang M Biochem Biophys Res Commun. 348(2):374-8. doi: 10.1016/j.bbrc.2006.07.106. September 22, 2006. View on PubMed.
Tissue heterogeneity of the mammalian mitochondrial proteome. Johnson DT, Harris RA, French S, Blair PV, You J, Bemis KG, Wang M, Balaban RS Am J Physiol Cell Physiol. 292(2):C689-97. doi: 10.1152/ajpcell.00108.2006. August 23, 2006. View on PubMed.
Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer. Srirangam A, Mitra R, Wang M, Gorski JC, Badve S, Baldridge L, Hamilton J and 10 others Clin Cancer Res. 12(6):1883-96. doi: 10.1158/1078-0432.CCR-05-1167. March 15, 2006. View on PubMed.
A systems biology case study of ovarian cancer drug resistance. Chen JY, Shen C, Yan Z, Brown DP, Wang M Comput Syst Bioinformatics Conf. :389-98. 2006. View on PubMed.
beta-Tubulin mutations are associated with resistance to 2-methoxyestradiol in MDA-MB-435 cancer cells. Gökmen-Polar Y, Escuin D, Walls CD, Soule SE, Wang Y, Sanders KL, Lavallee TM and 4 others Cancer Res. 65(20):9406-14. doi: 10.1158/0008-5472.CAN-05-0088. October 15, 2005. View on PubMed.
Identification of serum N-acetylmuramoyl-l-alanine amidase as liver peptidoglycan recognition protein 2. Zhang Y, van der Fits L, Voerman JS, Melief MJ, Laman JD, Wang M, Wang H and 5 others Biochim Biophys Acta. 1752(1):34-46. doi: 10.1016/j.bbapap.2005.07.001. August 31, 2005. View on PubMed.
The impact of blood contamination on the proteome of cerebrospinal fluid. You JS, Gelfanova V, Knierman MD, Witzmann FA, Wang M, Hale JE Proteomics. 5(1):290-6. doi: 10.1002/pmic.200490084. January 2005. View on PubMed.
Human ribosomal protein S3 interacts with DNA base excision repair proteins hAPE/Ref-1 and hOGG1. Hegde V, Wang M, Deutsch WA Biochemistry. 43(44):14211-7. doi: 10.1021/bi049234b. November 9, 2004. View on PubMed.
Characterization of human ribosomal protein S3 binding to 7,8-dihydro-8-oxoguanine and abasic sites by surface plasmon resonance. Hegde V, Wang M, Deutsch WA DNA Repair (Amst). 3(2):121-6. February 3, 2004. View on PubMed.
Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase. Bidasee KR, Zhang Y, Shao CH, Wang M, Patel KP, Dincer UD, Besch HR Jr Diabetes. 53(2):463-73. February 2004. View on PubMed.
Comparative proteomic analysis of human CD34+ stem/progenitor cells and mature CD15+ myeloid cells. Tao W, Wang M, Voss ED, Cocklin RR, Smith JA, Cooper SH, Broxmeyer HE Stem Cells. 22(6):1003-14. doi: 10.1634/stemcells.22-6-1003. 2004. View on PubMed.
Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase. Wang ZM, Li X, Cocklin RR, Wang M, Wang M, Fukase K, Inamura S, Kusumoto S, Gupta D, Dziarski R J Biol Chem. 278(49):49044-52. doi: 10.1074/jbc.M307758200. December 5, 2003. View on PubMed.
Proteomic analysis of differential protein expression induced by ultraviolet light radiation in HeLa cells. Decker ED, Zhang Y, Cocklin RR, Witzmann FA, Wang M Proteomics. 3(10):2019-27. doi: 10.1002/pmic.200300473. October 2003. View on PubMed.
Rapid determination of advanced glycation end products of proteins using MALDI-TOF-MS and PERL script peptide searching algorithm. Zhang Y, Cocklin RR, Bidasee KR, Wang M J Biomol Tech. 14(3):224-30. September 2003. View on PubMed.
Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors/calcium-release channels. Bidasee KR, Nallani K, Yu Y, Cocklin RR, Zhang Y, Wang M, Dincer UD, Besch HR Jr Diabetes. 52(7):1825-36. July 2003. View on PubMed.
Identification of methylation and acetylation sites on mouse histone H3 using matrix-assisted laser desorption/ionization time-of-flight and nanoelectrospray ionization tandem mass spectrometry. Cocklin RR, Wang M J Protein Chem. 22(4):327-34. May 2003. View on PubMed.
Identity and localization of advanced glycation end products on human beta2-microglobulin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Cocklin RR, Zhang Y, O'Neill KD, Chen NX, Moe SM, Bidasee KR, Wang M Anal Biochem. 314(2):322-5. March 15, 2003. View on PubMed.
Biochemical analysis of the damage recognition process in nucleotide excision repair. You JS, Wang M, Lee SH J Biol Chem. 278(9):7476-85. doi: 10.1074/jbc.M210603200. February 28, 2003. View on PubMed.
Cellular uptake of beta2M and AGE-beta2M in synovial fibroblasts and macrophages. O'Neill KD, Chen NX, Wang M, Cocklin R, Zhang Y, Moe SM Nephrol Dial Transplant. 18(1):46-53. January 2003. View on PubMed.
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