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Nicholas Ingolia

Position - Company  
Staff Member (PI) - Department of Embryology Carnegie Institution for Science Oct 2010 - Present
Degree - University  
Ph.D., Biology - Harvard University 2000 - 2006
Publication Info
Observation of dually decoded regions of the human genome using ribosome profiling data. Michel AM, Roy Choudhury K, Firth AE, Ingolia NT, Atkins JF, Baranov PV Genome Res. :. doi: 10.1101/gr.133249.111. May 16, 2012. View on PubMed.
The translational landscape of mTOR signalling steers cancer initiation and metastasis. Hsieh AC, Liu Y, Edlind MP, Ingolia NT, Janes MR, Sher A, Shi EY and 12 others Nature. 485(7396):55-61. doi: 10.1038/nature10912. February 22, 2012. View on PubMed.
High-resolution view of the yeast meiotic program revealed by ribosome profiling. Brar GA, Yassour M, Friedman N, Regev A, Ingolia NT, Weissman JS Science. 335(6068):552-7. doi: 10.1126/science.1215110. February 3, 2012. View on PubMed.
Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Ingolia NT, Lareau LF, Weissman JS Cell. 147(4):789-802. doi: 10.1016/j.cell.2011.10.002. November 11, 2011. View on PubMed.
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D Nature. 476(7358):88-91. doi: 10.1038/nature10245. August 3, 2011. View on PubMed.
Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery. Takacs JE, Neary TB, Ingolia NT, Saini AK, Martin-Marcos P, Pelletier J, Hinnebusch AG, Lorsch JR RNA. 17(3):439-52. doi: 10.1261/rna.2475211. January 10, 2011. View on PubMed.
Mammalian microRNAs predominantly act to decrease target mRNA levels. Guo H, Ingolia NT, Weissman JS, Bartel DP Nature. 466(7308):835-40. doi: 10.1038/nature09267. August 12, 2010. View on PubMed.
Molecular basis of infrared detection by snakes. Gracheva EO, Ingolia NT, Kelly YM, Cordero-Morales JF, Hollopeter G, Chesler AT, Sánchez EE, Perez JC, Weissman JS, Julius D Nature. 464(7291):1006-11. doi: 10.1038/nature08943. April 15, 2010. View on PubMed.
Genome-wide translational profiling by ribosome footprinting. Ingolia NT Methods Enzymol. 470:119-42. doi: 10.1016/S0076-6879(10)70006-9. 2010. View on PubMed.
Rapid creation and quantitative monitoring of high coverage shRNA libraries. Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT Nat Methods. 6(6):443-5. doi: 10.1038/nmeth.1330. May 17, 2009. View on PubMed.
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Ingolia NT, Ghaemmaghami S, Newman JR, Weissman JS Science. 324(5924):218-23. doi: 10.1126/science.1168978. April 10, 2009. View on PubMed.
Systems biology: Reverse engineering the cell. Ingolia NT, Weissman JS Nature. 454(7208):1059-62. doi: 10.1038/4541059a. August 28, 2008. View on PubMed.
Positive-feedback loops as a flexible biological module. Ingolia NT, Murray AW Curr Biol. 17(8):668-77. doi: 10.1016/j.cub.2007.03.016. April 17, 2007. View on PubMed.
The ups and downs of modeling the cell cycle. Ingolia NT, Murray AW Curr Biol. 14(18):R771-7. doi: 10.1016/j.cub.2004.09.018. September 21, 2004. View on PubMed.
Topology and robustness in the Drosophila segment polarity network. Ingolia NT PLoS Biol. 2(6):e123. doi: 10.1371/journal.pbio.0020123. June 15, 2004. View on PubMed.
Signal transduction. History matters. Ingolia NT, Murray AW Science. 297(5583):948-9. doi: 10.1126/science.1075222. August 9, 2002. View on PubMed.
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