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Paulo Bettencourt

Position - Company  
Research Assistant - Animal Facilities and Immunology Department Instituto Gulbenkian de Ciência (IGC)

My responsibilities were the genetic control and heath monitoring of multiple knockout and transgenic mouse strains, as well as the maintenance of many different mouse colonies. I was also involved in training activities for students and professionals.

Additionally, I was involved in a research project that is, the “Analysis of the Recombination Activating Genes 1 and 2”. This has led to the production of my MSc thesis at the University of Manchester.

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Apr 2004 - Jul 2007
Research Assistant - Cenix Bioscience, GmbH

I worked in the therapeutic unit of Cenix to test the efficacy of RNA interference (RNAi) in vivo, in the mouse model. I played an active role in the Caenorhabditis elegans functional genome wide RNAi screennig, where we successfully completed more than 99% of the C. elegans genes (Nature 2005, 434: 462-469).

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Aug 2001 - May 2003
Research Assistant - Microbiology Department Instituto de Higiene e Medicina Tropical

Working on the project "Extraction and Purification of Lipidic Compounds of the Mycobacterium tuberculosis cell wall”.

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Aug 1994 - Nov 1997
Degree - University  
BSc, Biotechnology - Instituto Superior de Humanidades e Tecnologias 1991 - 1995
PhD, Molecular and Cellular Biology - University of Lisbon

I am writting the thesis at the moment.

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2007 - Present
Publication Info
Statin-Induced Low Cholesterol is Not Associated With Poor Outcome in Chronic Heart Failure. Silva S, Lourenço P, Paulo C, Ferreira E, Lebreiro A, Sousa A, Mascaranhas J, Patacho M, Araujo JP, Bettencourt P J Cardiovasc Pharmacol Ther. :. doi: 10.1177/1074248411429967. December 14, 2011. View on PubMed.
Attitudes and anxiety levels of medical students towards the acquisition of competencies in communication skills. Loureiro EM, Severo M, Bettencourt P, Ferreira MA Patient Educ Couns. 85(3):e272-7. doi: 10.1016/j.pec.2011.07.005. December 2011. View on PubMed.
Third year medical students perceptions towards learning communication skills: implications for medical education. Loureiro E, Severo M, Bettencourt P, Ferreira MA Patient Educ Couns. 85(3):e265-71. doi: 10.1016/j.pec.2011.04.009. December 2011. View on PubMed.
Prognostic value of neutrophil gelatinase-associated lipocalin in acute heart failure. Alvelos M, Lourenço P, Dias C, Amorim M, Rema J, Leite AB, Guimarães JT, Almeida P, Bettencourt P Int J Cardiol. :. doi: 10.1016/j.ijcard.2011.07.080. August 26, 2011. View on PubMed.
Indirect calibration between clinical observers - application to the New York Heart Association functional classification system. Severo M, Gaio R, Lourenço P, Alvelos M, Bettencourt P, Azevedo A BMC Res Notes. 4:276. doi: 10.1186/1756-0500-4-276. August 3, 2011. View on PubMed.
Prognostic implications of diuretic dose in chronic heart failure. Martins J, Lourenço P, Araújo JP, Mascarenhas J, Lopes R, Azevedo A, Bettencourt P J Cardiovasc Pharmacol Ther. 16(2):185-91. doi: 10.1177/1074248410388807. June 2011. View on PubMed.
Population-based study on the prevalence of spirometric obstructive pattern in Porto, Portugal. Mascarenhas J, Falcão H, Lourenço P, Paulo C, Patacho M, Bettencourt P, Azevedo A Respir Care. 56(5):619-25. doi: 10.4187/respcare.00698. May 2011. View on PubMed.
Neutrophil gelatinase-associated lipocalin in the diagnosis of type 1 cardio-renal syndrome in the general ward. Alvelos M, Pimentel R, Pinho E, Gomes A, Lourenço P, Teles MJ, Almeida P, Guimarães JT, Bettencourt P Clin J Am Soc Nephrol. 6(3):476-81. doi: 10.2215/CJN.06140710. March 2011. View on PubMed.
B-type natriuretic peptide measured in serum--calibration using plasma samples for research purposes. Severo M, Pereira M, Bettencourt P, Gaio R, Azevedo A Clin Lab. 57(11-12):1015-9. 2011. View on PubMed.
Higher C-reactive protein predicts worse prognosis in acute heart failure only in noninfected patients. Lourenço P, Paulo Araújo J, Paulo C, Mascarenhas J, Friões F, Azevedo A, Bettencourt P Clin Cardiol. 33(11):708-14. doi: 10.1002/clc.20812. November 2010. View on PubMed.
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Sönnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM and 25 others Nature. 434(7032):462-9. doi: 10.1038/nature03353. March 24, 2005. View on PubMed.
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