Missing Avatar

Luke Lightning

Senior Director, Research - Alquest Therapeutics

Position - Company  
VP of Business Development - TechCentralSF

• Created a directory of Bay Area-based biopharma companies, service providers, and investors and conducted outreach to these entitites.
• Developed collaborations and sponsorships with San Francisco based tech groups and companies (QB3 at UCSF, CIRM, ChinaSF, Burrill, CACO-PBS, CABS, swissnex, Ricerca Biosciences, IAS).
• Worked to establish TechCentralSF as San Francisco’s exclusive online directory resource and collaborative community for High Tech, Biotech, and Cleantech sectors.
• Major products of this effort were the launch of (Bio)TechCentralSF in March 2011 at UCSF Mission Bay as well as 15 other Tech-based networking events in 10 months.

Show details
Nov 2010 - Sep 2011
Associate Director, DMPK - ARYx Therapeutics

• Represented the DMPK group in Discovery and Development project team meetings
• Actively participated in Discovery team meetings in multiple therapeutic areas
• Results: 4 compounds from Discovery entered clinical trials
• Interfaced daily with the Chemistry, Pharmacology, and Clinical team leaders
• Wrote and contributed SRB reviewed reports for INDs and IBs
• Addressed questions raised during due diligence for partnering activities
• Outlined strategies for achieving goals within company framework and research budget
• Composed a White Paper on at least one therapeutic area or target per year
• Developed in-house CYP450 induction and inhibition and transporter assays
• Trained, supervised, and instituted career development plans for DMPK personnel

Show details
Feb 2008 - Feb 2010
Senior Scientist II, DMPK - ARYx Therapeutics

• Represented the DMPK group in Discovery project team meetings
• Actively participated in Discovery team meetings in multiple therapeutic areas
• Interfaced daily with the Chemistry, Pharmacology, and Clinical team leaders
• Composed a White Paper on at least one therapeutic area or target per year
• Trained, supervised, and instituted career development plans for DMPK personnel

Show details
Apr 2004 - Feb 2008
Assistant Professor - Purdue University

• Recruited Ph.D. seeking students and designed research programs for each student
• Supervised six scientists (1 post-Ph.D. and 2-3 graduate and 2 undergraduate students)
• Taught undergraduate and graduate courses that on Pharmacology, Pharmacokinetics, Drug Metabolism, Biochemistry, and Bioanalytical Chemistry
• Submitted comprehensive research grants to various federal funding agencies
• Managed a research budget and was the decision maker for purchase of lab equipment
• Collaborated with other world class investigators to achieve research group milestones

Show details
Jun 2001 - Aug 2003
Postdoctoral Scholar - University of California, San Francisco

• Objective: to perturb the enzymatic activity of human heme oxygenase (HO) using site directed mutagenesis of the wild-type enzyme
• Generated site-directed mutants of human HO using PCR
• Collaborated with other scientists to achieve goals and publish results
• Expressed and purified HO and HO mutants
• Extraction of hemes and modified hemes from mutant HOs
• Biochemical characterization, kinetic analysis, and LC/UV and LC/MS analysis of HO and HO mutants

Show details
Aug 1998 - Jun 2001
Senior Director, Research - Alquest Therapeutics Mar 2010 - Present
Founder - MogulDex

• Provided guidance to Ruby, HTML5, PHP, and MySQL programmers using lean startup principles to create a minimum viable product in 4 months.
• Gathered feedback on user experience and implemented suggested improvements on the MVP.

Show details
Nov 2011 - Present
Organizer - Native American Heritage Night

• Coordinated event activities with multiple Bay Area Native American organizations to prepare for the 2012 NAHN at AT&T Park when the SF Giants play the Texas Rangers on June 8, 2012.

Show details
Nov 2011 - Present
DMPK Consultant - Carmot Therapeutics

• Designed DMPK and bioanalytical protocols and evaluated research work performed by CROs

Show details
Mar 2010 - Present
Degree - University  
PhD, Medicinal Chemistry - University of Washington 1993 - 1998
BA, Chemistry - Carleton College 1989 - 1993
  • Luke Lightning hasn't added any publication information yet...

  • Luke Lightning hasn't received any ratings yet...