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Fulvio D'Acquisto

Reader in Immunopharmacology - William Harvey Research Limited
London, GB
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Position - Company  
Reader in Immunopharmacology - William Harvey Research Limited

Biochemical Pharmacology

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2011 - Present
Degree - University  
PhD, Experimental Pharmacology - University of Naples, Italy 1996 - 1999
Publication Info
IL-17A increases ADP-induced platelet aggregation. Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D'Acquisto F Biochem Biophys Res Commun. 408(4):658-62. doi: 10.1016/j.bbrc.2011.04.080. May 20, 2011. View on PubMed.
Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature. Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F Blood. 116(20):4288-96. doi: 10.1182/blood-2010-02-270520. November 18, 2010. View on PubMed.
Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4- CD8- T cells. Maione F, Paschalidis N, Iqbal AJ, Crompton T, Perretti M, D'Acquisto F Autoimmunity. 43(8):672-81. doi: 10.3109/08916931003678296. April 7, 2010. View on PubMed.
Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Paschalidis N, Huggins A, Rowbotham NJ, Furmanski AL, Crompton T, Flower RJ, Perretti M, D'Acquisto F Cell Cycle. 9(4):784-93. February 15, 2010. View on PubMed.
Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1. Paschalidis N, Iqbal AJ, Maione F, Wood EG, Perretti M, Flower RJ, D'Acquisto F J Neuroinflammation. 6:33. doi: 10.1186/1742-2094-6-33. November 13, 2009. View on PubMed.
On the adaptive nature of annexin-A1. D'Acquisto F Curr Opin Pharmacol. 9(4):521-8. doi: 10.1016/j.coph.2009.04.007. May 27, 2009. View on PubMed.
Interleukin 17 sustains rather than induces inflammation. Maione F, Paschalidis N, Mascolo N, Dufton N, Perretti M, D'Acquisto F Biochem Pharmacol. 77(5):878-87. doi: 10.1016/j.bcp.2008.11.011. March 1, 2009. View on PubMed.
Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Perretti M, D'Acquisto F Nat Rev Immunol. 9(1):62-70. doi: 10.1038/nri2470. January 2009. View on PubMed.
Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation. Huggins A, Paschalidis N, Flower RJ, Perretti M, D'Acquisto F FASEB J. 23(4):985-96. doi: 10.1096/fj.08-119040. November 24, 2008. View on PubMed.
Annexin-A1: a pivotal regulator of the innate and adaptive immune systems. D'Acquisto F, Perretti M, Flower RJ Br J Pharmacol. 155(2):152-69. doi: 10.1038/bjp.2008.252. July 21, 2008. View on PubMed.
Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells. D'Acquisto F, Paschalidis N, Raza K, Buckley CD, Flower RJ, Perretti M Rheumatology (Oxford). 47(5):636-9. doi: 10.1093/rheumatology/ken062. April 4, 2008. View on PubMed.
Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. D'Acquisto F, Paschalidis N, Sampaio AL, Merghani A, Flower RJ, Perretti M Eur J Immunol. 37(11):3131-42. doi: 10.1002/eji.200636792. November 2007. View on PubMed.
Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. Vong L, D'Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat V, Perretti M J Biol Chem. 282(41):29998-30004. doi: 10.1074/jbc.M702876200. October 12, 2007. View on PubMed.
Annexin-1 modulates T-cell activation and differentiation. D'Acquisto F, Merghani A, Lecona E, Rosignoli G, Raza K, Buckley CD, Flower RJ, Perretti M Blood. 109(3):1095-102. doi: 10.1182/blood-2006-05-022798. February 1, 2007. View on PubMed.
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