Mass Spectrometry

Mass spectrometry is used to determine the mass, and thus identity, of a sample molecule. Ionized molecules passing it through a strong magnetic field will have their trajectories deflected by an amount proportional to their mass to charge ratio (m/z). This m/z spectrum can then be used to identify the molecule by comparison to a vast database of known molecular m/z spectra. To accomplish this, a mass spectrometry experiment is broken down into three basic steps. First, the sample is ionized. (If the sample is already a gas, it can be directly ionized; if it is a liquid or solid it must first be vaporized before ionization.) The ions are next organized into a stream that is guided through the mass analyzer, where they are exposed to magnetic fields that deflect their trajectory based on their mass. This deflection is recorded by the mass detector. There are many varied ways to ionize your sample. The process of ionizing a molecule can also break that molecule into fragments, in many cases in predictable patterns based on bond strengths and various functional groups that can yield structural information about the sample molecule. Hard ionization methods tend to produce lots of fragmentation, while soft ionization methods result in much less fragmentation. Thus, the m/z spectra will reflect the masses of the ionized sample analyte as well as ionized fragments of that analyte, resulting in a unique “fingerprint” for that molecule. There are also multiple methods for perturbing the ions’ flight and detecting the ions. Combining different methods of ionization, deflection and detection make mass spectrometry a versatile technique with relevance across a broad range of scientific areas.

We found 84 labs offering this service

$20.00 USD
per Sample
1379874917605_1bb87d41d15fe27b500a4bfcde01bb0e

Catonsville, Maryland
1379874917605_1bb87d41d15fe27b500a4bfcde01bb0e
Millis ScientificCatonsville, Maryland
  • 20 Services
  • 1 Member
  • 100% Positive Reviews
  • 8 Projects Completed
  • No endorsements

Our main workhorse for GC-MS based services is a state of the art system comprising a Waters Quattro GC triple quadrupole mass spectrometer interfaced to a Thermo TraceGC gas chromatograph.

Typical applications include:
-Volatile and semi-volatile compound identification using NIST mass spectral library Show more »

Our main workhorse for GC-MS based services is a state of the art system comprising a Waters Quattro GC triple quadrupole mass spectrometer interfaced to a Thermo TraceGC gas chromatograph.

Typical applications include:
-Volatile and semi-volatile compound identification using NIST mass spectral library
-Quantification of volatile and semi-volatile compound in complex matrices.

Millis Scientific's analytical scientists are highly experienced and knowledgeable in the application of GC-MS analyses to a wide variety of industries ranging from Food & Beverage to Pharmaceuticals and much more. Experience, fast turnaround, clear concise written reports, and person to person service are provided to help customers resolve their analytical and technical challenges.
The pricing is typical for large (>100 samples) batches.

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$75.00 USD
per Hour
1352588488858_5e19539007fbb5c1d8afdf0f79a93097

College Station, Texas
1352588488858_5e19539007fbb5c1d8afdf0f79a93097
TAMU Protein Chemistry LabTexas A&M UniversityCollege Station, Texas
  • 17 Services
  • 2 Members
  • 100% Positive Reviews
  • 12 Projects Completed
  • No endorsements

0.25 hour minimum; does not include sample preparation. Pricing varies with project requirements. Please contact the facility.

$88.26 USD
per Hour
1340747422000

Tampa, Florida
  • 100% Positive Reviews
  • 9 Projects Completed
  • No endorsements

ESI MS and MS/MS are performed at an hourly rate on an AB/Sciex QStar Elite instrument for molecular weight measurements with mass measurement accuracy less than 10 ppm and for structural characterization by tandem mass spectrometry. Individual samples can be manually infused and characterized at a rate of 6-12 per hour. For larger... Show more »

ESI MS and MS/MS are performed at an hourly rate on an AB/Sciex QStar Elite instrument for molecular weight measurements with mass measurement accuracy less than 10 ppm and for structural characterization by tandem mass spectrometry. Individual samples can be manually infused and characterized at a rate of 6-12 per hour. For larger batches of samples that require the same type of analysis, flow injection analysis could be used for automated sample analysis at higher rates (30-60 per hour).

Data can be provided in PowerPoint or summarized in reports. Individual files can be provided as .wiff (AB/Sciex format) or exported as ASCII rtext.

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$60.00 USD
per Hour
1352600217167_47f5ac1d1c1f1961047f03946640b17d

Lincoln, Nebraska
  • 100% Positive Reviews
  • 5 Projects Completed
  • No endorsements
$50.00 USD
per Sample
1352591431482_a2336ed1c2cc707a7d464a3906810725

Rensselaer, New York
1352591431482_a2336ed1c2cc707a7d464a3906810725
Proteomics Core FacilityCenter for Functional GenomicsRensselaer, New York
  • 41 Services
  • 1 Member
  • 100% Positive Reviews
  • 4 Projects Completed
  • No endorsements
$60.00 USD
per Hour
1355241939756_ea3368b8129fe67a01946f7b3833364f

St. Louis, Missouri
  • 100% Positive Reviews
  • 3 Projects Completed
  • No endorsements

PerkinElmer ELAN DRC II ICP-MS
Academic Service Rate: $60/hr
Industry Service rate: $160/hour

$168.85 USD
per Sample
1363985591932_145375dfb8ed1b7723376b467bd3f18f

Rochester, New York
1363985591932_145375dfb8ed1b7723376b467bd3f18f
Proteomics CoreUniversity of Rochester Medical CenterRochester, New York
  • 3 Services
  • 1 Member
  • 100% Positive Reviews
  • 1 Project Completed
  • No endorsements

Trypsin digestion of single protein (band/spot), rapid LC-MS/MS, followed by Mascot & X!Tandem search, report sent as Scaffold project or user friendly PDF. Good for simple samples of low complexity, like top ten protein detection

Protein chemistry sample preparation
Have our highly experienced staff prepare your... Show more »

Trypsin digestion of single protein (band/spot), rapid LC-MS/MS, followed by Mascot & X!Tandem search, report sent as Scaffold project or user friendly PDF. Good for simple samples of low complexity, like top ten protein detection

Protein chemistry sample preparation
Have our highly experienced staff prepare your samples, run your IPs, or elute/process your samples, conduct clean ups and preparation for LC-MS/MS analysis.
Price: $46.05 USD per Sample

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Price on request
1314398464000

Kinexus Bioinformatics Corporation
1314398464000
Kinexus Bioinformatics CorporationVancouver, British Columbia
  • 15 Services
  • 2 Members

Vancouver, British Columbia
1314398464000
Kinexus Bioinformatics CorporationVancouver, British Columbia
  • 15 Services
  • 2 Members
  • 100% positive reviews
  • 2 Projects Completed
  • No endorsements

Turnaround time: ~2-8 weeks depending on scope of work

$50.00 USD
per Sample
1382659988879_974dd2ae6f12e835af48727f80f18232

San Jose, California
1382659988879_974dd2ae6f12e835af48727f80f18232
Climax Laboratories, Inc.San Jose, California
  • 7 Services
  • 1 Member
  • No reviews
  • No completed projects
  • No endorsements
$120.00 USD
per Sample
1331320859000

Ontario, California
1331320859000
Advanced Analytical Testing ServiceOntario, California
  • 17 Services
  • 2 Members
  • 100% Positive Reviews
  • 5 Projects Completed
  • No endorsements

Instrument
HP 5890 GC - HP 5970 MSC

100% positive ratings across 3 reviews.