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Shotgun DNA Sequencing
Shotgun sequencing in general describes a technique for sequencing long regions of DNA. The shotgun part refers to breaking the region to be sequenced into many small fragments. These fragments were then sequenced and computationally reassembled to yield the sequence of the original region. When combined with next generation sequencing technologies such as Roche's GS-FLX platform, shotgun DNA sequencing can be a powerful tool for large region or whole genome sequencing.
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