Science Exchange Concierge
A dedicated scientist with a master's degree or PhD can identify the most qualified service providers for your project from our network of publicly and privately listed providers.
We found 0 results for SBF-SEM
For more results try searching for across all experimental services.
Serial block face scanning electron microscopy (SBFSEM) creates three dimensional (3D) images of very small samples by repeatedly sectioning and scanning a block face with an electron beam. In SBFSEM, the sample is dried (biological samples must be fixed), stained with heavy metals, and embedded in a polymer to create the block face. The sample is then kept under vacuum in the SEM chamber and thin sectioned by a device called a microtome. Electrons are released from an emission source and focused into a beam that scans over the block face after each sectioning in a raster pattern. The collected electrons are processed into an image of the surface of each block face and the sections are reconstructed into a 3D image. SBFSEM is useful for imaging the smallest cellular networks that require high resolution such as neuronal circuits as well as imaging organelle orientation and composition in cells. (Credit: Brooke Anderson-White)
Science Exchange is the fastest and safest way to order scientific services. All providers have passed a qualification process and agreed to pre-negotiated legal terms that protect your confidentiality and IP.