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Embryoid Body Formation
Embryoid bodies form as ball-like aggregates of embryonic stem cells when those cells are grown in suspension, as opposed to adherently. Embryoid bodies undergo similar differentiation paths as adherently cultured ESCs, but due to their 3D structures, can form microtissues that bear similarities to tissues in vivo. Embryoid body formation triggers spontaneous differentiation along the three major germ lineages.
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