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ZenBio

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Research Triangle Park, North Carolina, US

About ZenBio

Zen-Bio, Inc. (ZB) is a leading global provider of advanced cell-based solutions and services to the life science, cosmetics, and personal care communities. The company, founded in 1995, was a pioneer in adipose derived stem cells (ASCs) and continues this legacy providing cutting edge human primary cell... Show more »

Zen-Bio, Inc. (ZB) is a leading global provider of advanced cell-based solutions and services to the life science, cosmetics, and personal care communities. The company, founded in 1995, was a pioneer in adipose derived stem cells (ASCs) and continues this legacy providing cutting edge human primary cell culture products and services. Our mission is to provide the highest quality human cell systems, reagents and contract services to our research partners, to develop and commercialize innovative research tools, leverage our expertise through research and development and strategic alliances, and accelerate discovery.

Custom Tissue Procurement Services
ZenBio offers cells, tissue, and serum from a diverse group of donor populations. Products are available from mixed donor lots, individual donor lots and a variety of disease states such as type II diabetes, hypertension, and others.

Customized Cell Solutions
ZenBio offers customers exceptional versatility in addressing specific project requirements with our robust custom cell-based assay development and services capabilities. Experience a seamless workflow... customized to meet your rigorous project needs.

Metabolic Disease Contracts
ZenBio offers a variety of assays to test compounds as potential diabetes or obesity therapies. Customers can choose from any of the following assays or we can design a custom program tailored to each client's specific research needs.

ZenSkin™ Products and Services
ZenBio has developed a dedicated solutions platform delivering products, services and expertise to assist in the emerging and diverse research field of skin. From initial donor-specific tissue acquisition to full thinkness skin testing or 3D skin equivalents, the ZenBio research team can deliver dermal research capabilities to accelerate client projects and meet objectives rapidly in a cost-effective approach minimizing time, and resources.

High Content Assay Development and Screening Services
ZenBio offers a variety of assays to using our ArrayScan XTI. Customers can choose from any of the following assays or we can design a custom program tailored to each client's specific research needs.

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Our Services (197)


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Human Tissue Punch/Biopsy

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Human Tissue Derived products

Human Tissue Derived products

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Bioanalytical Assays

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Cell Counting Kit-8 (CCK8) Assays

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Antibody Optimization

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Antibody Screening

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DNA Quantification

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Cell Banking

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Cell Expansion

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High Content Screening

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ZenBio offers a variety of assays to using our ArrayScan XTI. Customers can choose from any of the following assays or we can design a custom program tailored to each client's specific research needs.

ZenBio offers a variety of assays to using our ArrayScan XTI. Customers can choose from any of the following assays or we can design a custom program tailored to each client's specific research needs.

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RNA Extraction and Purification

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Cell-Based Assays

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ZenBio offers customers exceptional versatility in addressing specific project requirements with our robust custom cell-based assay development and services capabilities. Experience a seamless workflow... customized to meet your rigorous project needs.

ZenBio offers customers exceptional versatility in addressing specific project requirements with our robust custom cell-based assay development and services capabilities. Experience a seamless workflow... customized to meet your rigorous project needs.

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Human Tissue Procurement

Price on request

ZenBio offers cells, tissue, and serum from a diverse group of donor populations. Products are available from mixed donor lots, individual donor lots and a variety of disease states such as type II diabetes, hypertension, and others.

ZenBio offers cells, tissue, and serum from a diverse group of donor populations. Products are available from mixed donor lots, individual donor lots and a variety of disease states such as type II diabetes, hypertension, and others.

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Glucose Uptake Assays

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Diabetes is a prevalent metabolic disease affecting more than 25 million Americans. About 90% to 95% of patients have non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes.

Diabetes is a prevalent metabolic disease affecting more than 25 million Americans. About 90% to 95% of patients have non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes.

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Lipolysis

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Lipolysis plays a central role in the regulation of energy balance. Lipolysis is the process in which triglycerides (TG) are hydrolyzed into glycerol and free fatty acids. This process releases free fatty acids (FFA) into the bloodstream where they may be either re-esterified by the adipocyte or travel to other tissues and exert... Show more »

Lipolysis plays a central role in the regulation of energy balance. Lipolysis is the process in which triglycerides (TG) are hydrolyzed into glycerol and free fatty acids. This process releases free fatty acids (FFA) into the bloodstream where they may be either re-esterified by the adipocyte or travel to other tissues and exert other effects throughout the body. Elevated adipocyte lipolysis has been observed in obese and diabetic individuals (Arner 1996). Excessive free fatty acid production is believed to contribute to insulin resistance in skeletal muscle that is observed in obesity. Hormone sensitive lipase is the rate-limiting enzyme catalyzing triglyceride breakdown. Perilipins, one of the PAT (perilipins, adipophilin, TIP47 proteins) family of lipid-associated proteins, are implicated in adipocyte lipolysis by mediating the interaction of HSL with the triacylglycerol molecule (Brasaemle et al. 2004; reviewed in, Tansey et al. 2004.) The presence of these proteins corresponds to lipolytic stimulation in cultured adipocytes (Braemle et al. 2004).

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Cellular Metabolism Assays

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Human Epidermal Melanocytes

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Diabetes Human DNA

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Human Epidermal Keratinocytes

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Human Foreskin Fibroblasts

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Human Neonatal Dermal Fibroblasts

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Human Umbilical Vein Endothelial Cells

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Cytotoxicity Assays

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Human Tracheal Epithelial Cells

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Human Hepatic Sinusoidal Endothelial Cells

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Human Chondrocytes

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In vitro Neurotoxicity Testing

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Human Bronchial Epithelial Cells

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Human Renal Tubular Epithelial Cells

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In vitro Hepatotoxicity Testing

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Human Mammary Epithelial Cells

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Cytotoxicity Assays

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In vitro Diabetes Models

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Human Adult Dermal Fibroblasts

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Cell Products

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Lipolysis Assay

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Adipogenesis Assay

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Human DNA and RNA Samples

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Biospecimens

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Human Tissue

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Human Tissue Services

Human Tissue Services

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Cellular Health & Metabolism Assays

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Biology

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Toxicology

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Cell Culture Media and Reagents

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Human Primary Cells

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In vitro Disease Models

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Functional & Cell Type Specific Assays

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Biochemistry & Molecular Biology

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Cells and Tissues

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Human Biospecimen Collection

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Pharmacology & Toxicology

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In vitro Toxicity Testing

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Lipid Services

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Human Biospecimens

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Cell-Based Screening Methods

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Cell-Based Screening Methods Services

Cell-Based Screening Methods Services

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Lipid Accumulation Assays

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Lipid accumulation assays provide the tools to study the compounds that stimulate cultured human adipocyte differentiation or lipogenesis. Such compounds may be PPAR. agonists or a combination of thiazolidinediones and glucocorticoids that are potentially useful in the treatment of diabetes. Our assays measure potential PPAR... Show more »

Lipid accumulation assays provide the tools to study the compounds that stimulate cultured human adipocyte differentiation or lipogenesis. Such compounds may be PPAR. agonists or a combination of thiazolidinediones and glucocorticoids that are potentially useful in the treatment of diabetes. Our assays measure potential PPAR agonists or glucocorticoid analogs. Assays include cellular accumulation of lipid after proscribed periods of time in culture, with and without compounds of interest.

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In vitro Skeletal Muscle Models

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Human Pan-T Cells

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Human Pan-T Cells, Negatively Selection, 5 million

Human Pan-T Cells, Negatively Selection, 5 million

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Human CD8+ T-Cells

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Human CD4+ T-Cells

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Human CD19+ B-Cells

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Mitochondrial Stress Tests

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Fresh Human Tissue

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Human RNA

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Human DNA

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Human Primary Immune Cells

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Animal Biospecimens

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Frozen Human Tissue

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Prospective Human Tissue Collection

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Nucleic Acid Services

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In vitro Phototoxicity Testing

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Melanin Content Assay

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Human Liver-Derived Endothelial Cells

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Human Kupffer Cells

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Drug Discovery

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In vitro Acne Models

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Serum Free Cell Culture Medium

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Specialized Cell-Based Assays

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In vitro Reporter Gene Assays

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Cell Signaling Analyses

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DNA Damage & Repair Assays

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Immune Cell Assays

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Cryopreserved Human Hepatocytes

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Lipid Extraction and Purification

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Cellular Bioenergetics

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Oxidative Phosphorylation Assay

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Lipid Hydroperoxide Assay

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Thiol Detection Assays

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Glutathione Assays

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Oxidative Stress Assays

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Custom Cell Model Development

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Transporter & Cell Uptake Assays

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Cell Death Assays

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Cell Viability & Proliferation Assays

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Human Biofluids

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Manufacturing Services

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High Throughput Cell Adhesion Screening

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Rheumatoid Arthritis Human DNA

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Arthritis Human DNA

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In vitro Skin Irritation/Sensitization Testing

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Human Skin Acute Inflammation Assays

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Glucose Release Assays

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Diabetes Human RNA

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In vitro Insulin Secretion Assay

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Adipogenesis & Adipolysis Assays

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Fatty Acid Oxidation Assays

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Glycogen Assays

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Rheumatoid Arthritis Human RNA

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Arthritis Human RNA

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Human Natural Killer Cells

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Human B Cells

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Human Lens Epithelial Cells

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Human Iris Pigment Epithelial Cells

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Human Oral Keratinocytes

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Human Retinal Pigment Epithelial Cells

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Human Umbilical Vein Smooth Muscle Cells

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Human Hepatocytes

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Human Hepatic Stellate Cells

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Human Pulmonary Fibroblasts

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Human Splenic Fibroblasts

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Human Mammary Fibroblasts

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Human Gingival Fibroblasts

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Human Dermal Microvascular Endothelial Cells

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Bone Marrow Mononuclear Cells

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Human Fetal Liver Cells

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ROS Assays

Reactive Oxygen Species Assays
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Human Fetal Dermal Fibroblasts

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Human Microglia

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Lipid Detection

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Cell-Based ATP Binding Assays

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Human Primary Cell Isolation

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Heat Shock Protein Assays

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DNA Extraction and Purification

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Assay Development Consulting

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Human Bone Marrow

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Endothelial Barrier Screening Platform

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Mesenchymal Stem Cell Toxicity Testing

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In vitro Hematoxicity Testing

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FBS Testing

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Stem Cell Media

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Functional T-cell Suppression Assays

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Stem Cell Assays

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Artificial Synapse Formation Assay

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Neuronal Assays

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Biospecimen Management and Storage

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Formulation Services

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Experimental Services

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Biochemical Assays

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Cell Invasion & Migration Assays

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Media Screening

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Express Media Service

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Custom Mouse Media

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Drug Discovery & Development

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Drug Discovery & Development Services

Drug Discovery & Development Services

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In vitro Immunotoxicity Testing

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Tissue Processing

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Imaging & Spectroscopy

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Angiogenesis & Endothelial Cell Assays

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Banked Leukocyte DNA

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Primary Cell Lines

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Cell Lines

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Stable Cell Lines for High Throughput Screening

Stable Cell Lines for High Throughput Screening

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Assay Development

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Exosome Isolation and Characterization

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Liver specific exosome detection and biomarker detection (Exosome Isolation and Characterization)

Liver specific exosome detection (Exosome Isolation and Characterization)

Liver specific exosome detection by flow cytometry (Exosome Isolation and Characterization)

Liver specific exosome detection and biomarker detection (Exosome Isolation and Characterization)

Liver specific exosome detection (Exosome Isolation and Characterization)

Liver specific exosome detection by flow cytometry (Exosome Isolation and Characterization)

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Whole Slide Imaging/Digital Slide Scanning

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Cell-Based Compound Screening

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Scientific Consulting

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Elisa Kit Development

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Mammalian Cell Culture

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MTT and MTS Assays

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Normal Human Leukopak

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Fresh Human LeukoPak - Normal Full

Fresh Human LeukoPak - Normal Full

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Human Whole Blood & PBMCs

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Human Whole Blood & PBMCs Services

Human Whole Blood & PBMCs Services

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Antibody Services

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Antibody Services

Antibody Services

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Protein Services

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Protein Services

Protein Services

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Cell and Tissue Culture

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Cell and Tissue Culture Services

Cell and Tissue Culture Services

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RNA Services

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RNA Services

RNA Services

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Diseased Human Leukopak

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Diabetes Crohn's disease Celiac disease

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Biomarker Analysis

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Human Cord Blood Plasma

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Diseased Human Peripheral Blood Mononuclear Cells (PBMCs)

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Breast cancer

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In vitro Drug Efficacy Testing

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Immunoassays

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Custom ORF Cloning Services

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In vitro Hemolysis Assay

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Compound Profiling

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Cell Migration Assays

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RNA Quantification

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Gene Expression Analysis

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Genotyping and Gene Expression Assays

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Genotyping Services

Genotyping Services

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DNA Services

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DNA Services

DNA Services

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Bioanalysis

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Bioanalysis Services

Bioanalysis Services

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Pharmacology

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Pharmacology Services

Pharmacology Services

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Multiplex Biomarker Analysis

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Bioconjugation/Chemical Crosslinking

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Fluorescence Imaging Plate Reader (FLIPR) Assays

Fluorescence Imaging Plate Reader
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Cytokine Release Assay

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Custom Cell-Based Assay Development

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Kinase Assays

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Protein-RNA Interaction Analysis

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Dendritic Cell Generation

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