Ymir Genomics has two goals: 1) provide new tools to facilitate the discovery of biomarkers from biofluids such as blood and urine and 2) use these tools to discover novel urine biomarkers to fight human disease. We have developed a novel, fast, and low cost protocol for isolating extra-cellular vesicles (exosomes + other vesicles) and/or extra-cellular RNA from urine that gives a higher yield than current commercial kits or ultracentrifugation. This method works especially well for more dilute urine samples. We are currently using this and other methods to identify urine biomarkers for several indications. We are also offering this method as a service for others.
Extra-cellular vesicle Isolation From Urine Biofluid
We have developed a novel, rapid and efficient, method of isolating intact extra-cellular vesicles (including exosomes) from Urine. Our method is superior in yield to ultracentrifugation or other commercial methods. It works especially well in the more dilute urine samples which are intractable by other methods. We can elute the vesicles in a variety of buffers suitable for functional proteomics, transcriptomics, or other applications. Our price is negotiable for first time clients or for clients with a large number of samples.
Extra-cellular RNA Isolation from Urine.
We have developed a novel, rapid and efficient method of isolating extra-cellular RNA (including miRNA) from Urine. Our method includes vesicular RNA and extra-cellular protein-RNA complexes and is superior in yield to ultracentrifugation or other commercial methods. It works especially well in the more dilute samples and for extra-cellular miRNA preps which can be intractable for other methods. Our pricing is negotiable for first time clients or for clients with a large number of samples.
Extra-cellular Urine miRNA profiling:
We isolate extra-cellular urine miRNA and profile the prep with either qRT-PCR or one of several commercial arrays. This Service is in Beta testing and the price is negotiable.
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