1402442844114 6a0ac92e4243f0ee638cd7733d1c8fa9

WuXi AppTec - Research Service Division

ic 9.7/10 Overall Rating 100% Positive
ic 56 Orders Completed
Shanghai, Shanghai, CN

About WuXi AppTec - Research Service Division

Founded: 2000 Divison of: WuXi AppTec

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of... Show more »

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

WuXi AppTec has successfully established a fully integrated services and technology platform during the past decade. The company built its initial capabilities around discovery chemistry and has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services, DMPK/ADME, discovery biology, pharmacology, formulation, toxicology, genomic services, biologics manufacturing services, antibody and biological research reagent manufacturing and sales, and most recently clinical research and regulatory services.

WuXi AppTec has developed from four founders and a single laboratory in December 2000 to over 7,000 employees and 3 million square feet of laboratory and manufacturing space. The company is actively improving its capabilities and capacity through new expansions in its global business. Capitalizing on the great advantage of conducting R&D services both in China and in the U.S., WuXi AppTec is building an alternative R&D engine to serve the global life-science industry.


Certifications:
- CLIA - China
- GLP from OECD & EU - China
- ISO/IEC 17025:2005 - US
- ISO 13485:2003 - US
- FDA (HCT/Ps) - US
- AATB - US


Standard sample shipment requirements: WuXi AppTec can handle all forms of shipping from standard ground to express overnight and from ambient temperature to dry ice.


Relevant publications:
- Coburn, Craig. A.; Meinke, Peter T.; Chang, Wei; Fandozzi, Christine M.; Graham, Donald J.; Hu, Bin; Huang, Qian; Kargman, Stacia; Kozlowski, Joseph; Liu, Rong; McCauley, John A.; Nomeir, Amin A.; Soll, Richard M.; Vacca, Joseph P.; Wang, Dahai; Wu, Hao; Zhong, Olsen, David B.; Ludmerer, Steven W. Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity. ChemMedChem (2013), 8(12), 1930-1940.

  • Coburn, Craig A.; Luo, Yunfu; Cui, Mingxiang; Wang, Jiabing; Soll, Richard; Dong, Jingchao; Hu, Bin; Lyon, Michael A.; Santarelli, Vincent P.; Kraus, Richard L.; Gregan, Yun; Wang, Yi; Fox, Steven V.; Binns, Jacquelyn; Doran, Scott M.; Reiss, Duane R.; Tannenbaum, Pamela L.; Gotter, Anthony L.; Meinke, Peter T.; Renger, John J. Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K2P9.1 (TASK-3). ChemMedChem (2012), 7(1), 123-133
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Our Services (122)


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Biochemical Compound Screening

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Photochemical Synthesis

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GPCR Assays

G-Protein Coupled Receptor Assay
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Compound Library Design

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Glucose Uptake Assays

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CRISPR Screening

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Knock-In Cell Lines

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CRISPR/Cas9 Knockout Cell Lines

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Cell Line Derived Xenograft (CDX) Models

Cell Line Derived Xenograft Models
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Rare Disease Animal Models

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Luciferase Assays

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Kinase Assays

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GPCR Screening and Profiling

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Enzyme Assays

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Animal Models and Studies

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Liver Fibrosis Animal Models

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Erectile Dysfunction Animal Models

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Diabetes Animal Models

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Nonhuman primates

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Obesity Animal Models

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Chronic Inflammatory Pain Animal Models

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Electrophysiology Animal Models

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Non-Human Primate Models

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Protein Purification

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Antibacterial Screening

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Medicinal Chemistry

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Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters functioning as... Show more »

Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters functioning as a local resource to our valued partners. WuXi’s local presence offers a range of advantages in
program management, strategic planning in projects of the collaboration, and streamlining of communications with WuXi’s China-based operations and execution teams.

We provide our customers with access to WuXi’s best-in-class fully integrated drug discovery and development platform to seamlessly progress programs from target through to preclinical candidate selection and beyond.

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Cell Line Characterization

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Chiral Chromatography

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High Throughput Screening (HTS)

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Compound Library Synthesis

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hERG Channel Inhibition Assay

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Off-Target Drug Effects

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Toxicology

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Protein Production

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Pharmacology & Toxicology

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Rabbit Guinea pig Mouse Rat Minipig

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Antivirals

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Hepatitis Animal Models

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Mouse Hepatitis B

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Antiviral Testing

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Cancer Cell Line Panels

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Immuno-oncology Assays

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In vitro Oncology Models

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In vitro Pharmacology Studies

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Liver Steatosis Animal Models

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Non-Alcoholic Steatohepatitis (NASH)

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Structure Determination

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Natural Product Isolation and Purification

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Cellular Immune Response Assay

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Cytokine Analysis

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Cell-Based Compound Screening

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Assay Development

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Radioisotope Production

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Mass Spectrometry

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X-ray Crystallography

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Compound Purification

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HPLC

High Performance Liquid Chromatography
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In vitro Disease Models

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Wet Chemical Analysis

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Chemical Analysis

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Solubility and Dissolution Testing

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Animal Behavior Studies

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Chemical Synthesis

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gram milligram kilogram ton

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Animal Glucose and Insulin Tolerance Testing

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OGTT, ipGTT, ivGTT urine glucose assays

OGTT, ipGTT, ivGTT urine glucose assays

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PPAR-Gamma Assays

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Ligand Binding Assays

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Insulin receptor, insulin growth factor 1 receptor radioligand binding and functional assay.

Insulin receptor, insulin growth factor 1 receptor radioligand binding and functional assay.

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Structural Biology

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Biochemical Assays

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Animal Learning, Memory, and Behavior Tests

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Natural Products

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Biology

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Hit Identification

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In vivo Toxicity Testing

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Guinea pig Mouse Rat

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Animal Model in vivo Analyses

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Guinea pig Mouse Rat

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Chromatography

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Model Organisms

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Reproductive System Animal Models

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Imaging & Spectroscopy

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Cellular Health & Metabolism Assays

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In vitro Reporter Gene Assays

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CNS/Neurology Animal Models

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In vitro Cardiotoxicity Screening

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Mouse Rat

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Animal Models of Disease

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Separation/Purification Services

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Synthetic Chemistry

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Transcription Factor Assays

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Virology Services

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Animal Cognition & Behavior Tests

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Radiochemistry

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Receptor Assays

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DNA Services

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Liquid Chromatography (LC)

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Hepatic Animal Models

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Chiral Resolution

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Cell-Based Screening Methods

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Cells and Tissues

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DNA Libraries

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Patient-Derived Xenograft (PDX)

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Chemistry and Materials

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Spectroscopy

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Biochemistry & Molecular Biology

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Protein Services

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Xenograft Models

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Antimicrobial Activity Testing

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Project Management

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In vitro Genetic Screening

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Drug Discovery

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Testing of Cell Lines

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Genetic Engineering

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Analytical Chemistry Services

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Cell-Based Assays

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Animal Physiology Analyses

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Immunoassays

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Pain/Neuropathy Animal Models

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Bioanalysis

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Cell Lines

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Viral Assays

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Biomolecular Interaction Analysis

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Nucleic Acid Services

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Mammalian Models

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Mammalian Cell Culture

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Toxicology

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Metabolic Animal Models

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Drug Discovery & Development

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Oncology Animal Models

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Microbiology

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Compound Libraries

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Compound Libraries Services

Compound Libraries Services

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  • Positive review for Chemical Synthesis:

    November 2017

    "My requested compound was made and delivered efficiently, and analysis showed high purity."

WuXi AppTec - Research Service Division has not received any endorsements.