1402442844114 6a0ac92e4243f0ee638cd7733d1c8fa9

WuXi AppTec - Research Service Division

Shanghai, China, CN

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

WuXi AppTec has successfully established a fully integrated services and technology platform during the past decade. The company built its initial capabilities around discovery chemistry and has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services,... Show more »

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

WuXi AppTec has successfully established a fully integrated services and technology platform during the past decade. The company built its initial capabilities around discovery chemistry and has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services, DMPK/ADME, discovery biology, pharmacology, formulation, toxicology, genomic services, biologics manufacturing services, antibody and biological research reagent manufacturing and sales, and most recently clinical research and regulatory services.

WuXi AppTec has developed from four founders and a single laboratory in December 2000 to over 7,000 employees and 3 million square feet of laboratory and manufacturing space. The company is actively improving its capabilities and capacity through new expansions in its global business. Capitalizing on the great advantage of conducting R&D services both in China and in the U.S., WuXi AppTec is building an alternative R&D engine to serve the global life-science industry.


Certifications:
- CLIA - China
- GLP from OECD & EU - China
- ISO/IEC 17025:2005 - US
- ISO 13485:2003 - US
- FDA (HCT/Ps) - US
- AATB - US


Standard sample shipment requirements: WuXi AppTec can handle all forms of shipping from standard ground to express overnight and from ambient temperature to dry ice.


Relevant publications:
- Coburn, Craig. A.; Meinke, Peter T.; Chang, Wei; Fandozzi, Christine M.; Graham, Donald J.; Hu, Bin; Huang, Qian; Kargman, Stacia; Kozlowski, Joseph; Liu, Rong; McCauley, John A.; Nomeir, Amin A.; Soll, Richard M.; Vacca, Joseph P.; Wang, Dahai; Wu, Hao; Zhong, Olsen, David B.; Ludmerer, Steven W. Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity. ChemMedChem (2013), 8(12), 1930-1940.

  • Coburn, Craig A.; Luo, Yunfu; Cui, Mingxiang; Wang, Jiabing; Soll, Richard; Dong, Jingchao; Hu, Bin; Lyon, Michael A.; Santarelli, Vincent P.; Kraus, Richard L.; Gregan, Yun; Wang, Yi; Fox, Steven V.; Binns, Jacquelyn; Doran, Scott M.; Reiss, Duane R.; Tannenbaum, Pamela L.; Gotter, Anthony L.; Meinke, Peter T.; Renger, John J. Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K2P9.1 (TASK-3). ChemMedChem (2012), 7(1), 123-133
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WuXi AppTec - Research Service Division has not listed any services.

GPCR Assays
G-Protein Coupled Receptor Assay
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Glucose Uptake Assay
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Cancer Animal Models
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Mouse
CRISPR Screening
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CRISPR Knock-in Cell Lines
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CRISPR Knock-out Cell Lines
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Immunoassay Services
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Cell Line Derived Xenograft (CDX) Models
Cell Line Derived Xenograft Models
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Medicinal Chemistry
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Rare Disease Animal Models
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Luciferase Assays
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Kinase Assays
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GPCR Screening and Profiling
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Enzyme Assay Services
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Animal Models and Studies
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Liver Fibrosis Animal Models
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Erectile Dysfunction Animal Models
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Diabetes Animal Models
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Non-human primates
Obesity Animal Models
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Chronic Inflammatory Pain Animal Models
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Electrophysiology Animal Models
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Non-Human Primate Models
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Protein Purification and Concentration
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Antibacterial Screening
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Medicinal Chemistry Services
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Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters... Show more »

Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters functioning as a local resource to our valued partners. WuXi’s local presence offers a range of advantages in
program management, strategic planning in projects of the collaboration, and streamlining of communications with WuXi’s China-based operations and execution teams.

We provide our customers with access to WuXi’s best-in-class fully integrated drug discovery and development platform to seamlessly progress programs from target through to preclinical candidate selection and beyond.

FTE rates are highly competitive and quotes can be provided upon request. Please see the attached brochures for more details.

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Cell Line Characterization
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Chiral Chromatography
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High Throughput Screening
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Library Design and Synthesis
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In vitro biochemical screening
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hERG Channel Inhibition Assay
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Off-Target Drug Effects
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Protein Production
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Pharmacology & Toxicology
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Antivirals
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Hepatitis Animal Models
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Mouse
Hepatitis B
Antiviral Testing
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Screening Multi Cancer Cell Lines
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Patient Derived Xenograft (PDX) Models
Patient-Derived Xenograft
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Immuno-oncology Assays
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In vitro Oncology Models
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In vitro Pharmacology Studies
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Liver Steatosis Animal Models
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NASH (Non-Alcoholic Steatohepatitis)
Chiral Resolution Services
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Structure Determination
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Natural Product Isolation and Purification
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Cellular Immune Response Assay
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Cytokine Analysis
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Cell-Based Compound Screening
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Analytical Chemistry Services
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Assay Development
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Radioisotope Production
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Mass Spectrometry
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X-ray crystallography
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Compound Purification
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HPLC
High Performance Liquid Chromatography
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In vitro Disease Models
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Wet Chemical Analysis
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Method development
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Chemical Analysis Services
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Solubility Studies
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Animal Behavior Studies
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Compound Synthesis
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Animal Glucose and Insulin Tolerance Testing
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OGTT, ipGTT, ivGTT urine glucose assays

OGTT, ipGTT, ivGTT urine glucose assays

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PPAR-Gamma Assays
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Ligand Binding Assays (LBA)
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Insulin receptor, insulin growth factor 1 receptor radioligand binding and functional assay.

Insulin receptor, insulin growth factor 1 receptor radioligand binding and functional assay.

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November 17, 2017

Positive review received for Compound Synthesis:

"My requested compound was made and delivered efficiently, and analysis showed high purity."

2017-09-02 10:53:00 -0700

Net Promoter Score of 9 received for Compound Synthesis.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.

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