1402442844114 6a0ac92e4243f0ee638cd7733d1c8fa9

WuXi AppTec

Shanghai China

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

WuXi AppTec has successfully established a fully integrated services and technology platform during the past decade. The company built its initial capabilities around discovery chemistry and has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services,... Show more »

Established in December 2000, WuXi AppTec (NYSE: WX) is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. As an innovation-driven and customer-focused company, WuXi AppTec provides a broad and integrated portfolio of services throughout the drug R&D process. Our services are designed to help our worldwide customers shorten the discovery and development time and lower the cost of drug and medical device R&D through cost-effective and efficient outsourcing solutions.

WuXi AppTec has successfully established a fully integrated services and technology platform during the past decade. The company built its initial capabilities around discovery chemistry and has further enhanced the integrated services with analytical services, bio-analytical services, process research, process development services, API manufacturing services, DMPK/ADME, discovery biology, pharmacology, formulation, toxicology, genomic services, biologics manufacturing services, antibody and biological research reagent manufacturing and sales, and most recently clinical research and regulatory services.

WuXi AppTec has developed from four founders and a single laboratory in December 2000 to over 7,000 employees and 3 million square feet of laboratory and manufacturing space. The company is actively improving its capabilities and capacity through new expansions in its global business. Capitalizing on the great advantage of conducting R&D services both in China and in the U.S., WuXi AppTec is building an alternative R&D engine to serve the global life-science industry.


Certifications:
- CLIA - China
- GLP from OECD & EU - China
- ISO/IEC 17025:2005 - US
- ISO 13485:2003 - US
- FDA (HCT/Ps) - US
- AATB - US


Standard sample shipment requirements: WuXi AppTec can handle all forms of shipping from standard ground to express overnight and from ambient temperature to dry ice.


Relevant publications:
- Coburn, Craig. A.; Meinke, Peter T.; Chang, Wei; Fandozzi, Christine M.; Graham, Donald J.; Hu, Bin; Huang, Qian; Kargman, Stacia; Kozlowski, Joseph; Liu, Rong; McCauley, John A.; Nomeir, Amin A.; Soll, Richard M.; Vacca, Joseph P.; Wang, Dahai; Wu, Hao; Zhong, Olsen, David B.; Ludmerer, Steven W. Discovery of MK-8742: An HCV NS5A Inhibitor with Broad Genotype Activity. ChemMedChem (2013), 8(12), 1930-1940.

  • Coburn, Craig A.; Luo, Yunfu; Cui, Mingxiang; Wang, Jiabing; Soll, Richard; Dong, Jingchao; Hu, Bin; Lyon, Michael A.; Santarelli, Vincent P.; Kraus, Richard L.; Gregan, Yun; Wang, Yi; Fox, Steven V.; Binns, Jacquelyn; Doran, Scott M.; Reiss, Duane R.; Tannenbaum, Pamela L.; Gotter, Anthony L.; Meinke, Peter T.; Renger, John J. Discovery of a Pharmacologically Active Antagonist of the Two-Pore-Domain Potassium Channel K2P9.1 (TASK-3). ChemMedChem (2012), 7(1), 123-133
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WuXi AppTec has not listed any services.

Whole Exome Sequencing
Starting at $950.00 USD per sample

100X Whole exome sequencing on HiSeq Platform: PE 2X125, including DNA sample QC, library construction, exome capture and sequencing

  • Sample request: >1ug DNA per sample
  • Data yield: Targeting 200X coverage with >10x coverage for greater than 98% of the targeted region; output >14G PF data
  • Exome capture kit:... Show more »

100X Whole exome sequencing on HiSeq Platform: PE 2X125, including DNA sample QC, library construction, exome capture and sequencing

  • Sample request: >1ug DNA per sample
  • Data yield: Targeting 200X coverage with >10x coverage for greater than 98% of the targeted region; output >14G PF data
  • Exome capture kit: Agilent SureSelectXT Human All Exon V6
  • Data QC criteria: average Q30 > 80%
  • Deliverables: raw data (FASTQ reads), Sample QC Report, Data QC Report
  • Turnaround time: 3-4 weeks after samples pass QC

150X Coverage is $1100
200X Coverage is $1500

We are flexible and can accommodate any request. For those non-standard project, please inquire for more details.

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Whole Genome Sequencing
Starting at $1,500.00 USD per sample

30X Whole genome sequencing on HiSeq X Platform: PE 2X150, including DNA sample QC, library construction and sequencing

  • Sample request: >1ug DNA per sample
  • Data yield: 30X coverage, 90G PF data
  • Data QC criteria: average Q30 > 75%
  • Deliverables: raw data (FASTQ reads), Sample QC Report, Data QC Report
    -... Show more »

30X Whole genome sequencing on HiSeq X Platform: PE 2X150, including DNA sample QC, library construction and sequencing

  • Sample request: >1ug DNA per sample
  • Data yield: 30X coverage, 90G PF data
  • Data QC criteria: average Q30 > 75%
  • Deliverables: raw data (FASTQ reads), Sample QC Report, Data QC Report
  • Turnaround time: 3-4 weeks after samples pass QC

40X Coverage - $2000
50X Coverage - $2500
60X Coverage - $2700
90X Coverage - $4400

We are flexible and can work with you to sequence at any depth. Please contact us to discuss further.

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Natural Product Isolation and Purification
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Structure Determination
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Chiral Resolution Services
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Custom Pain Animal Models
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Solubility Studies
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Pharmacology & Toxicology
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Protein Production
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hERG Channel Inhibition Assay
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Chemical Synthesis
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Digital PCR
Price on request

Gene Validation Services for Research:
Droplet Digital PCR (Collaboration with Clinical Diagnostics)

Gene Validation Services for Research:
Droplet Digital PCR (Collaboration with Clinical Diagnostics)

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Bio-Rad QX200 droplet digital PCR
Medicinal Chemistry Services
Price on request

Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters... Show more »

Medicinal Chemistry
Hit Identification & Target Validation
Hit-to-Lead Optimization
Lead Optimization & Preclinical Candidate Selection

We have highly experienced medicinal chemists located in key biopharma clusters of the United States and Europe. We are highly accomplished and industry-seasoned drug hunters functioning as a local resource to our valued partners. WuXi’s local presence offers a range of advantages in
program management, strategic planning in projects of the collaboration, and streamlining of communications with WuXi’s China-based operations and execution teams.

We provide our customers with access to WuXi’s best-in-class fully integrated drug discovery and development platform to seamlessly progress programs from target through to preclinical candidate selection and beyond.

FTE rates are highly competitive and quotes can be provided upon request. Please see the attached brochures for more details.

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HPLC
High Performance Liquid Chromatography
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Extractables and Leachables
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Chemical Analysis Services
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Blending
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Assay Development
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Nitric oxide synthase assays
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Drug Formulation
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Cell Line Characterization
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Compound Purification
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Process and Scale-Up Chemistry
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Chiral Chromatography
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General Histology & Pathology Services
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High Throughput Screening
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Drug Product Stability
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Radioisotope Production
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Metabolite Profiling
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Method development
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DMPK Services
Drug Metabolism and Pharmacokinetics Services
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Library Design and Synthesis
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X-ray powder diffraction
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X-ray crystallography
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Medical Device Development
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Preclinical
Wet Chemical Analysis
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Sterilization Services
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Sterility testing
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Preclinical Efficacy Studies
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Mass Spectrometry Services
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