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WMed Innovation Center - Mass Spectrometry Lab

Kalamazoo, MI, US

Western Michigan University School of Medicine Innovation Center (SMIC) is a 69,000-square-foot, purpose-built incubator/accelerator created to support life science startups and maturing companies. The mass spectrometry facility housed in the Innovation Center supports its clients and companies nationally through its fee-for-service operation. The facility is managed by Greg Cavey who has over 20 years of mass spectrometry experience. Gregs’ broad expertise allows a range of services to be offered including: medium throughput mass measurement, bioanalytical PK/PD analysis, proteomic and metabolomic profiling, protein characterization (intact mass, PTM analysis, protein ID, protein truncation), and antibody epitope mapping using hydrogen-deuterium exchange - mass spectrometry.

Services have been refined to provide customer satisfaction through quality data, fast turnaround, and reasonable cost. Many CROs provide... Show more »

Western Michigan University School of Medicine Innovation Center (SMIC) is a 69,000-square-foot, purpose-built incubator/accelerator created to support life science startups and maturing companies. The mass spectrometry facility housed in the Innovation Center supports its clients and companies nationally through its fee-for-service operation. The facility is managed by Greg Cavey who has over 20 years of mass spectrometry experience. Gregs’ broad expertise allows a range of services to be offered including: medium throughput mass measurement, bioanalytical PK/PD analysis, proteomic and metabolomic profiling, protein characterization (intact mass, PTM analysis, protein ID, protein truncation), and antibody epitope mapping using hydrogen-deuterium exchange - mass spectrometry.

Services have been refined to provide customer satisfaction through quality data, fast turnaround, and reasonable cost. Many CROs provide mass spectrometry services but few provide direct contact with the expert scientist to help with your next project or sample set.

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WMed Innovation Center - Mass Spectrometry Lab has not listed any services.

Biology
Price on request
Request a quote for more information about this service.
Bioanalytical Assays
Starting at $3,500.00 per run
  • Fast-turnaround for PK analysis with standard or client LC-MS/MS methods
  • Competitive pricing: $30-50/injection, $500/analyte std curve, $125-500/report
  • Extensive method development experience:sample preparation, HPC/UPLC, mass spectrometry
  • Data emailed as an Excel file
  • Fast-turnaround for PK analysis with standard or client LC-MS/MS methods
  • Competitive pricing: $30-50/injection, $500/analyte std curve, $125-500/report
  • Extensive method development experience:sample preparation, HPC/UPLC, mass spectrometry
  • Data emailed as an Excel file
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Waters 2795 (LC)
Micromass Quattro Micro Triple Quad API (MS/MS)
Waters Quattro Premier XE
Capillary HPLC
Waters NanoAcuity UPLC
Waters Quanlynx
Microsoft Excel
stable isotope internal standard
Protein Identification
Starting at $200.00 per run
  • Qtof mass spectrometry with nanoscale UPLC
  • SDS-PAGE gel bands: coomassie stained >50fmol protein
  • Protein Solution: minimum amount 100-200fmol in 25uL
  • Over 15 years experience performing this service
  • Turnaround time: 3-7 days
  • Data emailed as an Excel file
  • Qtof mass spectrometry with nanoscale UPLC
  • SDS-PAGE gel bands: coomassie stained >50fmol protein
  • Protein Solution: minimum amount 100-200fmol in 25uL
  • Over 15 years experience performing this service
  • Turnaround time: 3-7 days
  • Data emailed as an Excel file
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Qtof
Nanoscale UPLC
Mass Spectrometry
In-gel digest
Trypsin
Waters
Proteinlynx Global Server
Quadrupole time-of-flight
Protein ID
gel bands
High Resolution
Label Free Quantitative Proteomics
Starting at $400.00 per run
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is... Show more »
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is HIGHLY recommended at the START of a project
  • Turnaround time: 4-12 weeks depending on number of samples, sample type/prep.required, 1D or 2D analysis, reporting criteria
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Trypsin
Proteinlynx Global Server
Quadrupole time-of-flight
gel bands
Protein Quantification
1D and 2D Nanoscale UPLC
RapiGest
Protein Solution
Microsoft Excel - Pivot Tables
Custom Databases
Quantitative Proteomics
Label Free
Epitope Mapping
Price on request

Antibody Epitope Mapping by Hydrogen/Deuterium Exchange - Mass Spectrometry

  • Working knowledge of HDX analysis including sample requirements
  • Experienced with mAb epitope mapping
  • Projects include a feasability study, antibody-antigen titration, time-course analysis of unbound vs. antibody bound antigen, data analysis and... Show more »

Antibody Epitope Mapping by Hydrogen/Deuterium Exchange - Mass Spectrometry

  • Working knowledge of HDX analysis including sample requirements
  • Experienced with mAb epitope mapping
  • Projects include a feasability study, antibody-antigen titration, time-course analysis of unbound vs. antibody bound antigen, data analysis and reporting
  • Competitive 50-100pmol per injection sensitivity
  • Project consulting and detailed data review included
  • Turnaround time: 4-6 weeks per Ab/antigen pair
  • Cost commensurate with protein(s) being studied but typically $10-35K for an antibody-antigen pair
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Nanoscale UPLC
Mass Spectrometry
Proteinlynx Global Server
Quadrupole time-of-flight
High Resolution
Deuterium
Immobilized Pepsin
HD Examiner
monoclonal antibody
Mass Spectrometry
Starting at $50.00 per sample
  • 1-2 day turnaround for mass measurement w/o sample preparation
  • LC-MS mass measurement using C18 or C4 reverse-phase HPLC
  • Organic compounds 0.01mg/mL and 50uL
  • Protein solutions (no detergent) 10-20pmol/uL and 25-50uL
  • Custom analysis based on client needs
  • Cost for no prep. samples is $50 for small molecules, $200... Show more »
  • 1-2 day turnaround for mass measurement w/o sample preparation
  • LC-MS mass measurement using C18 or C4 reverse-phase HPLC
  • Organic compounds 0.01mg/mL and 50uL
  • Protein solutions (no detergent) 10-20pmol/uL and 25-50uL
  • Custom analysis based on client needs
  • Cost for no prep. samples is $50 for small molecules, $200 for intact protein mass, and $250 for accurate mass measurement (<10ppm)
  • Data emailed as a Powerpoint file
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LC-MS
Protein Intact Mass
Waters MaxEnt1 for protein electrospray spectrum deconvolution
Quantitative Proteomics
Price on request
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is... Show more »
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is HIGHLY recommended at the START of a project
  • Turnaround time: 4-12 weeks depending on number of samples, sample type/prep.required, 1D or 2D analysis, reporting criteria
« Show less
In-gel digest
Trypsin
Proteinlynx Global Server
Quadrupole time-of-flight
gel bands
1D and 2D Nanoscale UPLC
RapiGest
Microsoft Excel - Pivot Tables
SDS-PAGE
Imaging & Spectroscopy
Price on request
Request a quote for more information about this service.
Antibody Services
Price on request
Request a quote for more information about this service.
Protein Services
Price on request
Request a quote for more information about this service.
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2017-12-19 11:30:04 -0800

Net Promoter Score of 10 received for Mass Spectrometry.

Additional Ratings: satisfaction with deliverable: 7, satisfaction with timeliness: 10.
January 9, 2017

Positive review received for Bioanalytical Assays:

"We appreciated the responsiveness and service that Greg Cavey and his team provided. They were flexible with their schedule and pricing and were knowledgeable about the details of the assay. We appreciated also the clear and prompt communications that we had with Greg during the period of work. We look forward to working with Greg again in the future."

2016-12-09 11:28:07 -0800

Net Promoter Score of 10 received for Mass Spectrometry.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 9.
September 19, 2016

Positive review received for Mass Spectrometry:

"Very professional! I got my results the second day after they received the sample. The lab manager sent me the detailed MS spectrum and also explained the results to me. I will definitely collaborate with them again."

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