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WMed Innovation Center - Mass Spectrometry Lab

ic 9.8/10 Overall Rating 100% Positive
ic 13 Orders Completed
Kalamazoo, Michigan, US

About WMed Innovation Center - Mass Spectrometry Lab

Western Michigan University School of Medicine Innovation Center (SMIC) is a 69,000-square-foot, purpose-built incubator/accelerator created to support life science startups and maturing companies. The mass spectrometry facility housed in the Innovation Center supports its clients and companies nationally... Show more »

Western Michigan University School of Medicine Innovation Center (SMIC) is a 69,000-square-foot, purpose-built incubator/accelerator created to support life science startups and maturing companies. The mass spectrometry facility housed in the Innovation Center supports its clients and companies nationally through its fee-for-service operation. The facility is managed by Greg Cavey who has over 20 years of mass spectrometry experience. Gregs’ broad expertise allows a range of services to be offered including: medium throughput mass measurement, bioanalytical PK/PD analysis, proteomic and metabolomic profiling, protein characterization (intact mass, PTM analysis, protein ID, protein truncation), and antibody epitope mapping using hydrogen-deuterium exchange - mass spectrometry.

Services have been refined to provide customer satisfaction through quality data, fast turnaround, and reasonable cost. Many CROs provide mass spectrometry services but few provide direct contact with the expert scientist to help with your next project or sample set.

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Our Services (12)


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Bioanalytical Analysis LC/MS/MS

Starting at $30.00 per sample
  • Fast-turnaround for PK analysis with standard or client LC-MS/MS methods
  • Competitive pricing: $30-50/injection, $500/analyte std curve, $125-500/report
  • Extensive method development experience:sample preparation, HPLC/UPLC, tandem mass spectrometry
  • Data emailed as an Excel file
  • Fast-turnaround for PK analysis with standard or client LC-MS/MS methods
  • Competitive pricing: $30-50/injection, $500/analyte std curve, $125-500/report
  • Extensive method development experience:sample preparation, HPLC/UPLC, tandem mass spectrometry
  • Data emailed as an Excel file
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Waters 2795 (LC) Waters Quattro Premier XE Capillary HPLC Waters NanoAcuity UPLC stable isotope internal standard Waters Quanlynx Microsoft Excel Show 7 more tags Show less

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Epitope Mapping

Price on request

Antibody Epitope Mapping by Hydrogen/Deuterium Exchange - Mass Spectrometry

  • Working knowledge of HDX analysis including sample requirements
  • Experienced with mAb epitope mapping
  • Projects include a feasability study, antibody-antigen titration, time-course analysis of unbound vs. antibody bound antigen, data analysis and... Show more »

Antibody Epitope Mapping by Hydrogen/Deuterium Exchange - Mass Spectrometry

  • Working knowledge of HDX analysis including sample requirements
  • Experienced with mAb epitope mapping
  • Projects include a feasability study, antibody-antigen titration, time-course analysis of unbound vs. antibody bound antigen, data analysis and reporting
  • Competitive 50-100pmol per injection sensitivity
  • Project consulting and detailed data review included
  • Turnaround time: 4-6 weeks per Ab/antigen pair
  • Cost commensurate with protein(s) being studied but typically $10-35K for an antibody-antigen pair
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Nanoscale UPLC Deuterium Immobilized Pepsin monoclonal antibody Proteinlynx Global Server HD Examiner Mass Spectrometry QTof Show 8 more tags Show less

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Protein Identification

Starting at $200.00 per run
  • Qtof mass spectrometry with nanoscale UPLC
  • SDS-PAGE gel bands: coomassie stained >50fmol protein
  • Protein Solution: minimum amount 100-200fmol in 25uL
  • Over 15 years experience performing this service
  • Turnaround time: 3-7 days
  • Data emailed as an Excel file
  • Qtof mass spectrometry with nanoscale UPLC
  • SDS-PAGE gel bands: coomassie stained >50fmol protein
  • Protein Solution: minimum amount 100-200fmol in 25uL
  • Over 15 years experience performing this service
  • Turnaround time: 3-7 days
  • Data emailed as an Excel file
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Nanoscale UPLC In-gel digest Trypsin gel bands Waters Proteinlynx Global Server Protein ID Mass Spectrometry QTof Show 9 more tags Show less

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Label Free Quantitative Proteomics

Starting at $400.00 per run
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is HIGHLY... Show more »
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5 or 10 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is HIGHLY recommended at the START of a project
  • Turnaround time: 4-12 weeks depending on number of samples, sample type/prep.required, 1D or 2D analysis, reporting criteria
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1D and 2D Nanoscale UPLC Trypsin gel bands RapiGest Protein Solution Proteinlynx Global Server Microsoft Excel - Pivot Tables QTof Show 8 more tags Show less

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Mass Spectrometry

Starting at $50.00 per sample
  • 1-2 day turnaround for mass measurement w/o sample preparation
  • LC-MS mass measurement using C18 or C4 reverse-phase HPLC
  • Organic compounds 0.01mg/mL and 50uL
  • Protein solutions (no detergent) 10-20pmol/uL and 25-50uL
  • Custom analysis based on client needs
  • Cost for no prep. samples is $50 for small molecules, $200... Show more »
  • 1-2 day turnaround for mass measurement w/o sample preparation
  • LC-MS mass measurement using C18 or C4 reverse-phase HPLC
  • Organic compounds 0.01mg/mL and 50uL
  • Protein solutions (no detergent) 10-20pmol/uL and 25-50uL
  • Custom analysis based on client needs
  • Cost for no prep. samples is $50 for small molecules, $200 for intact protein mass, and $250 for accurate mass measurement (<10ppm)
  • Data emailed as a Powerpoint file
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Protein Intact Mass Waters MaxEnt1 for protein electrospray spectrum deconvolution LC-MS

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Quantitative Proteomics

Price on request
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5,10, and 20 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is... Show more »
  • Qtof Mass Spectrometry and nanoscale UPLC
  • Complex Protein Mixture Analysis
  • 1D or 2D (5,10, and 20 fraction) Nanoscale UPLC
  • Quantification based on Top 3 Analysis using AAA Quantified Peptide Standards
  • Minimum sample is 10-20ug total Protein Per Sample and >2ug/uL in detergent free buffer
  • Project Consulting is HIGHLY recommended at the START of a project
  • Turnaround time: 4-12 weeks depending on number of samples, sample type/prep.required, 1D or 2D analysis, reporting criteria
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1D and 2D Nanoscale UPLC In-gel digest Trypsin gel bands RapiGest Proteinlynx Global Server Microsoft Excel - Pivot Tables SDS-PAGE QTof Show 9 more tags Show less

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Protein Services

Price on request
Request a quote for more information about this service.

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Proteomics Consulting

Price on request
Request a quote for more information about this service.

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Custom Proteomics

Price on request
Request a quote for more information about this service.

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Peptide Mapping

Price on request
Request a quote for more information about this service.

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Protein Characterization

Price on request

Protein Characterization Services

Protein Characterization Services

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Hydrolyzed Amino Acid Analysis

Price on request
Request a quote for more information about this service.

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Greg Cavey

Lab Director/Manager
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Francisca Wong Coughlin

Business Manager
  • Positive review for Mass Spectrometry:

    December 2018

    "Greg Carvey went out of his way to make sure that our data was accurate and specific for the protein we were analyzing. I have used his services twice for Mass Spec and will use again."

  • Positive review for Bioanalytical Assays:

    January 2017

    "We appreciated the responsiveness and service that Greg Cavey and his team provided. They were flexible with their schedule and pricing and were knowledgeable about the details of the assay. We appreciated also the clear and prompt communications that we had with Greg during the period of work. We look forward to working with Greg again in the future."

  • Positive review for Mass Spectrometry:

    September 2016

    "Very professional! I got my results the second day after they received the sample. The lab manager sent me the detailed MS spectrum and also explained the results to me. I will definitely collaborate with them again."

WMed Innovation Center - Mass Spectrometry Lab has not received any endorsements.