West Coast Separations LLC

At Westcoast Separations, we have the capacity to purify on a scale from milligram to multi-gram scale.
Services include:

• Purification of chiral and achiral compounds (intermediates, research and non-GMP compounds, standards and etc.)
  
• Impurity isolation to give control over the chemistry by identifying impurities early.
  

With a collection of automated analytical and preparative systems (SFC-MS, LC-MS, prep-SFC) and various stationary phases (achiral and achiral), we begin method development by first screening of the library of column and based on the request, scale up method of choice to begin purification.

With our extensive range of library of columns, chiral stationary phases, automated column and solvent selection valves we will screen a minimum 50 chiral conditions within 4 hours using SFC.

Three Analytical SFC systems and five analytical HPLCs enable analytical samples to be processed quickly and efficiently.

• Enantiomeric purity determinations
  
• Purity confirmation of chiral and achiral compounds
  
• Purity confirmation of starting materials to final compounds
  
• Repeat of literature analysis
  
• Impurity isolation
  
• Stability study (forced or unforced degradation study)
  

Supplementing in-house method development with extensive screening of our column library and use of both HPLC and SFC