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Vijaya Pharmaceuticals, LLC

Research Triangle Park, North Carolina, US

Vijaya Pharmaceuticals, LLC (V-PHARMA) is a dynamic, cutting edge drug discovery company that provides a wide range of medicinal chemistry and synthetic organic chemistry services. Located in the renowned Research Triangle Park of North Carolina, USA. V-PHARMA is dedicated to serve the global pharmaceutical and biotechnology industries. Founded in 2009, V-PHARMA’s R&D laboratory is equipped with and has access to a full range of modern analytical equipment in order to generate highly reliable data on the compounds that the company delivers to its clients. The company also maintains excellent data integrity and follows the highest possible standards.

As a research-driven and client-focused company, V-PHARMA specializes in designing and synthesizing novel and drug-like scaffolds, libraries, and building blocks. It is capable of performing an extensive range of challenging organic synthesis projects with high... Show more »

Vijaya Pharmaceuticals, LLC (V-PHARMA) is a dynamic, cutting edge drug discovery company that provides a wide range of medicinal chemistry and synthetic organic chemistry services. Located in the renowned Research Triangle Park of North Carolina, USA. V-PHARMA is dedicated to serve the global pharmaceutical and biotechnology industries. Founded in 2009, V-PHARMA’s R&D laboratory is equipped with and has access to a full range of modern analytical equipment in order to generate highly reliable data on the compounds that the company delivers to its clients. The company also maintains excellent data integrity and follows the highest possible standards.

As a research-driven and client-focused company, V-PHARMA specializes in designing and synthesizing novel and drug-like scaffolds, libraries, and building blocks. It is capable of performing an extensive range of challenging organic synthesis projects with high quality and low costs. By providing a broad and integrated portfolio of chemistry services, the company management believes it is capable of assisting its drug discovery and development partners in shortening the product cycle and lowering the cost.

What makes V-PHARMA different is our:

  • Approach to significantly impact synthetic and medicinal chemistry-based projects both intellectually and technologically.
  • In-depth knowledge of complex organic synthesis including asymmetric synthesis and carbohydrate synthesis.
  • Risk-sharing partnership method to discover new medications.
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Compound Library Design
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The library design and synthesis service is dedicated and devoted to the examination, production, and design of a wide range of small organic molecule libraries for pharmaceutical, companies, research groups, and biotechnology companies. The library is created both by the customers’ demands and our company’s knowledge,... Show more »

The library design and synthesis service is dedicated and devoted to the examination, production, and design of a wide range of small organic molecule libraries for pharmaceutical, companies, research groups, and biotechnology companies. The library is created both by the customers’ demands and our company’s knowledge, capabilities, and molecular modeling skills. The compounds can also be purified based on the customer’s requirements and V-PHARMA can randomly synthesize part of a library in advance. We work with our clients and other computational chemists to supply the specific targeted groups.

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Compound Library Synthesis
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The library design and synthesis service is dedicated and devoted to the examination, production, and design of a wide range of small organic molecule libraries for pharmaceutical, companies, research groups, and biotechnology companies. The library is created both by the customers’ demands and our company’s knowledge,... Show more »

The library design and synthesis service is dedicated and devoted to the examination, production, and design of a wide range of small organic molecule libraries for pharmaceutical, companies, research groups, and biotechnology companies. The library is created both by the customers’ demands and our company’s knowledge, capabilities, and molecular modeling skills. The compounds can also be purified based on the customer’s requirements and V-PHARMA can randomly synthesize part of a library in advance. We work with our clients and other computational chemists to supply the specific targeted groups.

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Intellectual Property Consulting
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We can help gain wider and stronger IP protection when submitting a patent application by expanding the chemical diversity of the exemplified compounds. V-PHARMA can work with patent attorneys while filing the patent applications.

We can help gain wider and stronger IP protection when submitting a patent application by expanding the chemical diversity of the exemplified compounds. V-PHARMA can work with patent attorneys while filing the patent applications.

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Hit Identification
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Designated sets of small molecules or analogues can be synthesized for hit-to-lead identification programs. V-PHARMA can also help in identifying the lead by analyzing the competitors’ and pharmacological landscape (for validated targets) and initiate the fast follower program, if needed. We can also contribute to the opportunistic chemistry approach programs.

Designated sets of small molecules or analogues can be synthesized for hit-to-lead identification programs. V-PHARMA can also help in identifying the lead by analyzing the competitors’ and pharmacological landscape (for validated targets) and initiate the fast follower program, if needed. We can also contribute to the opportunistic chemistry approach programs.

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Hit to Lead and Lead Optimization
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Following a client driven approach we can prepare tailor-designed molecules to improve the potency and drug-like properties of the most promising compounds. We can integrate all currently available medicinal chemistry principles to make high quality molecules- a top priority thereby shortening the time required to select the right pre-clinical candidate.

Following a client driven approach we can prepare tailor-designed molecules to improve the potency and drug-like properties of the most promising compounds. We can integrate all currently available medicinal chemistry principles to make high quality molecules- a top priority thereby shortening the time required to select the right pre-clinical candidate.

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Medicinal Chemistry
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Medicinal Chemistry focuses on modifications of leads generated from natural compounds, high-throughput screening, and knowledge of validated therapeutic targets. Modern synthetic organic chemistry, including advanced purification, and spectroscopic technology is applied to finish the structure-activity relationship studies.... Show more »

Medicinal Chemistry focuses on modifications of leads generated from natural compounds, high-throughput screening, and knowledge of validated therapeutic targets. Modern synthetic organic chemistry, including advanced purification, and spectroscopic technology is applied to finish the structure-activity relationship studies.

We strive to design and synthesize novel molecules that maintain drug-like properties. These properties include the following:

· Structural Properties
· Physicochemical Properties
· Biochemical Properties
· Pharmacokinetics (PK) and toxicity

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Drug Discovery
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Antibiotic resistance has been a growing threat to human health for several years. Effectiveness of many antibacterial agents has declined worldwide, thus, limiting physicians' options to treat serious infections. The World Health Organization has stated that antibiotic resistance is one of the greatest healthcare challenges... Show more »

Antibiotic resistance has been a growing threat to human health for several years. Effectiveness of many antibacterial agents has declined worldwide, thus, limiting physicians' options to treat serious infections. The World Health Organization has stated that antibiotic resistance is one of the greatest healthcare challenges for the future. V-PHARMA would like to devote resources to work on a class of compounds to address this problem in a collaborative manner.

Partnership: V-PHARMA is open for collaboration to realize its business goals. This is a risk sharing approach where both the client and V-PHARMA put their own resources together to achieve the project goals. If successful, both parties share in the return on investment. IP is negotiated between the parties as part of the agreement. V-PHARMA is continuously looking for opportunities/collaborators to start any small molecule drug discovery effort including metabolic disorders.

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Compound Synthesis
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Broadening of Libraries' Chemical Diversity: We can synthesize non-commercially available screening compounds; thus increasing the commercial diversity and exclusivity of your chemical library. We can make every effort to identify the privileged scaffolds/drug-like chemo types with known/unknown pharmacophores.

Broadening of Libraries' Chemical Diversity: We can synthesize non-commercially available screening compounds; thus increasing the commercial diversity and exclusivity of your chemical library. We can make every effort to identify the privileged scaffolds/drug-like chemo types with known/unknown pharmacophores.

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Project Management, Consulting, & Support Services
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Biology
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DNA Libraries
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Chemistry and Materials
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Synthetic Chemistry
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Lead Identification and Validation
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Business Development Consulting
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DNA
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Drug Discovery & Development
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Biochemistry & Molecular Biology
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Compound Libraries
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Compound Libraries Services

Compound Libraries Services

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Nucleic Acid Services
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