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USA - Taconic Biosciences

39 Orders Completed
Rensselaer, New York, US

About USA - Taconic Biosciences

Divison of: Taconic Biosciences

Taconic Biosciences is a fully-licensed, global leader in genetically engineered rodent models and services. Founded in 1952, Taconic provides the best animal solutions so that customers can acquire, custom generate, breed, precondition, test, and distribute valuable research models worldwide.... Show more »

Taconic Biosciences is a fully-licensed, global leader in genetically engineered rodent models and services. Founded in 1952, Taconic provides the best animal solutions so that customers can acquire, custom generate, breed, precondition, test, and distribute valuable research models worldwide. Specialists in genetically engineered mouse and rat models, precision research mouse models, and integrated model design and breeding services, Taconic operates three service laboratories and six breeding facilities in the U.S. and Europe, maintains distributor relationships in Asia and has global shipping capabilities to provide animal models almost anywhere in the world.

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Certifications & Qualifications

AAALAC

Our Services (95)


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FVB Mouse Model

Price on request

FVB inbred mice (FVB/NTac) are ideal for generating transgenic mouse models, with prominent pronuclei for transgene microinjection and high reproductive performance.

  • Pronuclei of embryos are easily manipulated for microinjection
  • Inbred mouse strain with high reproductive performance
  • Females demonstrate excellent nurturing behavior
  • Males tend to fight when group housed

FVB inbred mice (FVB/NTac) are ideal for generating transgenic mouse models, with prominent pronuclei for transgene microinjection and high reproductive performance.

  • Pronuclei of embryos are easily manipulated for microinjection
  • Inbred mouse strain with high reproductive performance
  • Females demonstrate excellent nurturing behavior
  • Males tend to fight when group housed
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inbred mouse

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SJL Mouse Model

Price on request
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Project Management

Price on request

Outsourcing allows our clients to focus on their research and trust that the models they need are generated, bred, prepared and delivered efficiently.

Project plans are developed collaboratively; our scientific experts work together with you to ensure your project needs are met with budgets, timelines, health status, and cohort... Show more »

Outsourcing allows our clients to focus on their research and trust that the models they need are generated, bred, prepared and delivered efficiently.

Project plans are developed collaboratively; our scientific experts work together with you to ensure your project needs are met with budgets, timelines, health status, and cohort numbers optimized. In this process we will balance speed, quality, and price based on your preferences or project demands. A charter will be developed that includes methods and tools that will be used, deliverables, timelines, risks, budget and contact information.

*Scientific Program Managers
*Project Managers
*Scientific Compliance
*Production

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Mouse Rat

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Rodent Breeding

Price on request

Outsourcing allows our clients to focus on their research and trust that the models they need are generated, bred, prepared and delivered efficiently.

You've got the right mouse or rat for your study, now you need to generate cohorts to perform your study. Taconic Biosciences' GEMs Management team is ready to make that happen.... Show more »

Outsourcing allows our clients to focus on their research and trust that the models they need are generated, bred, prepared and delivered efficiently.

You've got the right mouse or rat for your study, now you need to generate cohorts to perform your study. Taconic Biosciences' GEMs Management team is ready to make that happen. Combining decades of animal husbandry and veterinary experience with access to the latest technologies and practices, our team delivers animals ready for your research.

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Mouse Rat Humanized Mouse in vivo

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Cryopreservation

Price on request

With cryopreservation you can maintain your research materials over the long term without having to maintain an active colony. Ensure the safety of your valuable research models and avoid genetic drift within your line. Free up valuable breeding space by cryopreserving lines not currently in use. Simplify collaboration by sharing... Show more »

With cryopreservation you can maintain your research materials over the long term without having to maintain an active colony. Ensure the safety of your valuable research models and avoid genetic drift within your line. Free up valuable breeding space by cryopreserving lines not currently in use. Simplify collaboration by sharing cryopreserved stock and avoid the transportation and quarantine issues associated with live animals. Extend the reproductive life of your colony and decrease the risk of disease transmission.

*Embryo cryopreservation
*Sperm cryopreservation

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Mouse Rat

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SNP Genotyping Data Analysis

Single nucelotide polymorphism genotyping data analysis
Price on request

Mouse 1449 SNP Panel
Panel of 1,449 SNP markers selected to maximize genetic information across 15 inbred strains Ideal for background characterization of most commonly use mouse strains.

  • 129S6/SvEvTac
  • BALB/cAnNTac
  • BALB/JBomTac
  • BALB/ABomTac
  • C3H/HeNTac
  • C57BL/6NTac
  • C57BL/6JBomTac
  • CB17SC
  • CBSCBG
    -... Show more »

Mouse 1449 SNP Panel
Panel of 1,449 SNP markers selected to maximize genetic information across 15 inbred strains Ideal for background characterization of most commonly use mouse strains.

  • 129S6/SvEvTac
  • BALB/cAnNTac
  • BALB/JBomTac
  • BALB/ABomTac
  • C3H/HeNTac
  • C57BL/6NTac
  • C57BL/6JBomTac
  • CB17SC
  • CBSCBG
  • DBA/1JBomTac
  • DBA/2NTac
  • FVB/NTac
  • NOD/MrkTac
  • NOG
  • SJL/JCrNTac
    Suitable for accelerated backcrossing or Speed Congenics

Mouse GenMon Panel
Panel of 96 SNP Markers suitable for quality control monitoring of the genetic background of inbred strains or lines to detect undesired genetic contamination or to assess genetic variability in some outbred stocks of mice
Not suitable for accelerated backcrossing or Quantitative Trait Loci (QTL) analysis

Mouse B6 SNP Panel
Panel of 96 SNP markers selected to differentiate C57BL/6 sub-strains
Ideal to differentiate C57BL/6N from C57BL/6J need at least 99.9% in C57BL/6 background. If in doubt it is better to do first the 1449 SNP Panel and verify that it really is in a C57BL/6 background

Rat GenMon Panel
Panel of 96 SNP markers suitable for routine quality control of inbred rat strains or for assessing genetic variability in certain outbred rat stocks
Not suitable for accelerated backcrossing or Quantitative Trait Loci (QTL) analysis

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Mouse Rat

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Rodent Rederivation

Price on request

Whether you require a simple reset of the health status or an accelerated build of your breeding colony, Taconic offers a derivation service to meet your needs. We understand that a successful research pipeline demands a balance of speed, price and quality. When your need for mice is critical, the time required to naturally expand... Show more »

Whether you require a simple reset of the health status or an accelerated build of your breeding colony, Taconic offers a derivation service to meet your needs. We understand that a successful research pipeline demands a balance of speed, price and quality. When your need for mice is critical, the time required to naturally expand a breeding colony to generate study cohorts often presents the greatest challenge. Taconic can employ in vitro fertilization and large scale embryo transfer methodologies to rapidly expand your colony to hundreds of animals with the same week of birth. These services allow you to move from donor animal to full production breeding within a matter of weeks. If you need to import animals but the health status is unacceptable, Taconic offers several options to "reset" the health status and produce a cohort that meets the health requirements of your facility.

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Mouse Rat

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Custom Animal Models

Price on request

Taconic Biosciences has the unique capability of combining the most experienced model generation team with a total comprehensive gene modification toolkit to provide customers the best solution to progress their program forward.

Model Acquisition
-Repository
-Embryology
-Custom Generation

**Transition Mutant to... Show more »

Taconic Biosciences has the unique capability of combining the most experienced model generation team with a total comprehensive gene modification toolkit to provide customers the best solution to progress their program forward.

Model Acquisition
-Repository
-Embryology
-Custom Generation

Transition Mutant to Model

  • Pilot Cohorts
    -Proof of Concept
    -Phenotype
    -Characterization
    -Speed to Cohort and Data
    -Creative Solutions

Scaled Breeding
-Multiple Health Profiles
-Economical Options
-Managed Productions Colonies
-Reliable Delivery
-Reproducibility from Cohort to Cohort
-Flexible Breeding Plans

Specialized Services
-Microbiome
-Backcrossing/ Speed Congeneics
-Fecal Microbiota Transplantation
-Custom Diets
-Transgene Mapping

Distribution
-Move to a Respository
-Market the model
-Distribute the model
-License the model

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Mouse Rat

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Zygosity Testing

Price on request

Transgene Zygosity Assay

  • Real-time PCR assay with relative quantitative data read-out
  • Appropriate for discerning wild-type, heterozygous and homozygous alleles with gene-targeted modifications

Transgene Copy Number Analysis

  • Real-time PCR assay with quantitative data read-out to allow for determination of transgene... Show more »

Transgene Zygosity Assay

  • Real-time PCR assay with relative quantitative data read-out
  • Appropriate for discerning wild-type, heterozygous and homozygous alleles with gene-targeted modifications

Transgene Copy Number Analysis

  • Real-time PCR assay with quantitative data read-out to allow for determination of transgene copy number
  • Appropriate for comparing different "founder" lines with the same transgene or monitoring transgene stability in lines with random inserted transgenes.
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Mouse Rat Real time qPCR

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Genotyping and Gene Expression Assays

Price on request

Inherent to breeding genetically modified mice and rats there is the need for regular genotyping. Accuracy, speed and access to your genotyping data are paramount to proper management of your studies. Through an exclusive distributorship with Transnetyx, Inc., your contract breeding project has access to all the services and... Show more »

Inherent to breeding genetically modified mice and rats there is the need for regular genotyping. Accuracy, speed and access to your genotyping data are paramount to proper management of your studies. Through an exclusive distributorship with Transnetyx, Inc., your contract breeding project has access to all the services and advantages that Transnetyx offers. Taconic also offers conventional genotyping assay design and optimization services, zygosity and transgene copy analysis.

Types of assays available:

  • Conventional PCR with qualitative data read-out by agarose gel or capillary electrophoresis
  • Real-time PCR assay with qualitative data read-out

Benefits:

  • Appropriate for discerning wild-type from hemizygous transgenic animals with randomly inserted transgene
  • Appropriate for discerning wild-type, heterozygous and homozygous alleles with gene-targeted modifications
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Mouse Rat PCR

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GEM Colony Care

Genetically Engineered Mouse Colony Care
Price on request
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Mouse

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Osteoarthritis Animal Models

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CRISPR/Cas9 Genome Editing

Price on request

Taconic offers a comprehensive CRISPR package by providing customers with a full suite of services.

  • Off-Target Prediction
  • Characterization of Founder Mosaicism
  • Custom Charters for Each Project
  • Seamless Transition into Colony Management
  • Rapid Expansion Downstream Breeding Strategies

Taconic offers a comprehensive CRISPR package by providing customers with a full suite of services.

  • Off-Target Prediction
  • Characterization of Founder Mosaicism
  • Custom Charters for Each Project
  • Seamless Transition into Colony Management
  • Rapid Expansion Downstream Breeding Strategies
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CRISPR

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Liver Disease Animal Models

Price on request
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Mouse Liver Disease

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Hepatitis Animal Models

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Mouse Hepatitis B

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Humanized CYP2D6 Mouse Models

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Mouse

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Athymic rnu:rnu Rat Model

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Rat

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Athymic Nude-Foxn1nu Mouse Model

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Mouse

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NMRI Nude Mouse Model

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Mouse

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SCID/BG Mouse Model

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Mouse

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C3H/He Mouse Model

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Mouse

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Nude NIH-rnu Mouse Model

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Mouse

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Sprague Dawley Rat Model

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Rat

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SCID Mouse Model

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Mouse

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C57BL/6 Mouse Model

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Mouse

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ALS Animal Models

Amyotrophic Lateral Sclerosis Animal Models
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Anxiety Animal Models

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Multiple Sclerosis Animal Models

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Viral Infection Animal Models

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Mouse Lymphocytic Choriomeningitis (LCMV)

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Malaria Animal Models

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Coronary Artery Disease Animal Models

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Goto Kakizaki Rats

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Rat

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Diabetes Animal Models

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Cardiovascular Metabolics Animal Models

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Epilepsy & Seizure Animal Models

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Transgenic Mouse Services

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Pronuclear Injection and Targeted Transgenesis

These models have been used to study the role of the human class I or class II restricted T cell repertoire in autoimmune disease, infectious disease, and vaccine development. They are also valued tools for evaluating human HLA restricted T cell-mediated vaccine efficacy in... Show more »

Pronuclear Injection and Targeted Transgenesis

These models have been used to study the role of the human class I or class II restricted T cell repertoire in autoimmune disease, infectious disease, and vaccine development. They are also valued tools for evaluating human HLA restricted T cell-mediated vaccine efficacy in oncology applications.

ExpressMODEL®:
-54 weeks for Experimental Cohort
-42 weeks Heterozygous Micd

Benefits:
Saves Time
Complies with 3Rs
Saves Money

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Mouse

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Schizophrenia Animal Models

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Genetically Engineered Mice

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Mouse

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Custom Cardiovascular Animal Models

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Human Tumor Xenograft Models

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Human

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Metastatic Tumor Animal Models

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Cancer Stem Cell Tumor Models

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Delayed-Type Hypersensitivity (DTH) Animal Models

Delayed Type Hypersensitivity Animal Models
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Cognition and Behavior Animal Models

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Knock-In Mouse Development

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Mouse

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Knockout Mouse Development

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Mouse

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Surgical Animal Models

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IBS/IBD Animal Models

Irritable Bowel Syndrome/Disease Animal Models
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Angiogenesis Animal Models

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Autoimmune Disease Animal Models

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Autoimmune hepatitis

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Rheumatoid Arthritis Animal Models

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Custom Oncology Animal Models

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Cardiovascular Disease

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Metabolic Disorders

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Animal Model Housing and Maintenance

Price on request

Taconic has several options for breeding your genetically engineered models. Options range from our Isolated Barrier Units to our Isolators or IVCs. Placement of your project into one or more of these options will be determined during project design with one of our Scientific Program Managers. All of Taconic's facilities are... Show more »

Taconic has several options for breeding your genetically engineered models. Options range from our Isolated Barrier Units to our Isolators or IVCs. Placement of your project into one or more of these options will be determined during project design with one of our Scientific Program Managers. All of Taconic's facilities are AAALAC International accredited demonstrating Taconic's adherence to strict guidelines for the care and use of animals.

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Mouse Rat

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Metabolic Animal Models

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Genetic Engineering

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Immunology Animal Models

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Model Organisms

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Oncology Animal Models

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Cardiovascular Animal Models

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Animal Models and Studies

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Reproductive System Animal Models

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Infectious Disease Animal Models

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Mouse Models

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Mouse

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Hepatic Animal Models

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Transgenic Animal Model Development

Price on request

These models have been used to study the role of the human class I or class II restricted T cell repertoire in autoimmune disease, infectious disease, and vaccine development. They are also valued tools for evaluating human HLA restricted T cell-mediated vaccine efficacy in oncology applications.

These models have been used to study the role of the human class I or class II restricted T cell repertoire in autoimmune disease, infectious disease, and vaccine development. They are also valued tools for evaluating human HLA restricted T cell-mediated vaccine efficacy in oncology applications.

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Mouse Rat

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CNS/Neurology Animal Models

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Rat Models

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Rat

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Patient-Derived Xenograft (PDX)

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Animal Models of Disease

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Rodent Models

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Rodents

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Hematology Animal Models

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Xenograft Models

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Cognitive, Behavioral, and Psychiatric Animal Models

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Inflammation Animal Models

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Mammalian Models

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Gastroenterology Animal Models

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Cryostorage and Cryoprocessing

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Cryostorage and Cryoprocessing Services

Cryostorage and Cryoprocessing Services

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Biospecimens

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Biospecimens Services

Biospecimens Services

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Sequencing Data Analysis and Management

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Sequencing Data Analysis Services

Sequencing Data Analysis Services

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Transgenic Genotyping

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Transgenic Rat Development

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Cell Microinjection

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Custom Mouse Models

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shRNA Plasmid Construction

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Rare Disease Animal Models

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Embryo (Strain) Cryorecovery

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Business Development, Marketing & Operations

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Business Development, Marketing & Operations Services

Business Development, Marketing & Operations Services

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Business Operations and Logistics Support

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Business Operations and Logistics Support Services

Business Operations and Logistics Support Services

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Plasmids and Vectors

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Plasmids and Vectors Services

Plasmids and Vectors Services

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Biology

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Biology Services

Biology Services

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Cells and Tissues

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Cells and Tissues Services

Cells and Tissues Services

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Biospecimen Management and Storage

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Biospecimen Management and Storage Services

Biospecimen Management and Storage Services

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Disease Names

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Disease Names Services

Disease Names Services

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