US Biomax, Inc.

Immunohistochemistry (IHC) service is provided to customers with specific needs for experiments on tissue array. These analyses are performed to localize the protein/gene of interest by using customer-supplied antibodies, DNA fragments or oligonucleotides on normal and diseased human tissues selected from US Biomax's vast selection of tissue arrays and tissue bank. These services are highly cost-effective and conducted to the highest standards to assist you in understanding function of your genes/proteins or in identification and validation of your potential diagnostic and therapeutic targets. The results can be given as a publishable, detailed pathology report accompanied by high-resolution digital photographs.

US Biomax uses an automated IHC stainer (Ventana) for high staining quality that ensures reproducible results. The research platform allows for customization of the reagents and protocol for best results. We offer multiple levels of detection amplification, allowing for highly sensitive assays to ensure that there are no false negatives. The use of a Streptavidin-Horseradish Peroxidase (HRP) minimizes nonspecific binding compared to biotin-based detection systems.

This service fee covers optimization for one antibody, testing pH 6.0 and 8.5 antigen retrieval and multiple dilutions for best results. One slide will be stained, and another can be stained at a different dilution. Isotype control staining and further slide staining is an additional fee.

Paraffin tissue processing, embedding, sectioning and staining and frozen tissue sectioning

US Biomax offers the use of Visiopharm for powerful and customizable image analysis. The following services are available for routine analysis:

• Automated quantification of cytoplasm, membrane, or nucleus staining
  
• Virtual double/triple staining by aligning features on individual cores. Applications include co-localization studies, and automated quantification of tumor regions only.
  
• A wide variety of algorithms for specific biomarkers shared by others at the Visiopharm App Center

Our tissue repository, tissue bank contains more than 600,000 paraffin tissue blocks, a large selection of tissue section slides of human cancer, normal tissue and rhesus normal fresh frozen tissue as well as paraffin blocks and slides.

Custom tissue microarray construction with customer's tissue blocks or tissues

Our tissue repository, tissue bank contains more than 600,000 paraffin tissue blocks, a large selection of tissue section slides of human cancer, normal tissue and rhesus normal fresh frozen tissue as well as paraffin blocks and slides.

Histological Staining Services