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UNE Rodent Behavior Core

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Biddeford, Maine, US

About UNE Rodent Behavior Core

The UNE behavior core is located in Biddeford, Maine, only 90 miles north of Boston. Our mission is to provide the research community with the highest level of technical expertise, training, instrumentation and related services for assessing behavior in animals. Through utilization of these services, researchers and trainees will gain insight into the function of the nervous system and mechanisms of acute and chronic pain.

Our staff have over 10 years of experience in rodent behavior and surgical methods for producing pain models. We can provide assistance in choosing behavioral test and in conducting statistical analysis for analyzing results.

The core is part of the Center of Biomedical Research Excellence (COBRE) for the study of Pain and Sensory Function, funded by NIGMS grant number, P20GM103643.

Our Services (21)


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Animal Behavior Studies

Price on request

Services Available:
General Behavioral Phenotyping: - Observational Screens - Motor Function: Open-field, Gait analysis, Grip strength, Rotorod

 

Pain/Sensory Testing: - Thermal: Hargreaves Test, Hot/Cold Plate, Tail-flick (Radiant & Immersion) - Mechanical: vonFrey Test - Chemical: Capsaicin Sensitization, Formalin, Carrageenan, CFA, Acetic Acid

 

Neurobehavioral Tests:
Psychiatric: Elevated plus maze, Light/dark box, Forced swim test, Tail suspension - Addiction: Place Preference, Tolerance/Dependence

 

Learning and Memory: Morris water maze, novel object recognition

 

Additional Services: - GI Transit - Assay consultation - Training in surgical techniques for small animal surgeries - PK Studies - Blood draw & Tissue collection


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Analgesic Animal Models

Price on request
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In vivo PK/PD Studies

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Gastrointestinal Disease Animal Models

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Conditioned Place Preference/Aversion Test

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Inflammation Animal Models

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Behavioral Phenotyping

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Formalin Test

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Chronic Inflammatory Pain Animal Models

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Acetic Acid Test

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Tail Suspension Test

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Elevated Plus Maze Animal Anxiety Test

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Forced Swim Test

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Morris Water Maze Assay

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Animal Fear Conditioning Studies

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Animal Learning, Memory, and Behavior Tests

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Object Recognition Test

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Animal Models and Studies

Price on request

Animal Models and Studies Services


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Surgical Animal Models

Price on request

Neuropathic:

  • L5 Transection
  • Sciatic Nerve Crush
  • Spared Dermatome

Post-surgical models:

  • Plantar Incision
  • Ovariectomy


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Dose Delivery Testing

Price on request

Systemic:

  • Subcutaneous, Intraperitoneal, Pellet implant, Oral gavage, Intravenous, Intramuscular

Central:

  • Intracerebroventricular, Intrathecal


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Animal Nociception/Pain Tests

Price on request

Thermal:

  • Hargreaves Test
  • Hot/Cold Plate
  • Tail-flick (radiant & immersion)

Mechanical:

  • vonFrey Assay


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DG

Denise Giuvelis

Behavior Core Manager

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