1352856118236 a2336ed1c2cc707a7d464a3906810725

UNC Metabolomics Laboratory

Durham, North Carolina, US

The UNC Metabolomics Laboratory is a collaborative resource for global and targeted metabolite profiling from a wide range of biological samples.

The lab is equipped with high-throughput robotic systems for the analysis of large samples sets.

Data analysis is performed using a number of commercial and home build software tools for the discovery of biomarkers and metabolic signatures of disease, toxicity or other biological outcomes.

UNC Metabolomics Laboratory has not listed any services.

Targeted Metabolomics
Price on request
Request a quote for more information about this service.
Biomarker Discovery
Price on request
Request a quote for more information about this service.
NMR data analysis
Nuclear magnetic resonance data analysis
Price on request

The raw NMR data is processed using a number of commercial NMR software packages, including ACD NMR Processor (ACD Lab, Toronto, Canada), Varian VNMRJ (Varian Inc., Palo Alto, CA), MestreNova (Santiago de Compostela, Spain) and Spinworks (Univ. of Manitoba, Canada)

The processed NMR data is then exported for multivariate... Show more »

The raw NMR data is processed using a number of commercial NMR software packages, including ACD NMR Processor (ACD Lab, Toronto, Canada), Varian VNMRJ (Varian Inc., Palo Alto, CA), MestreNova (Santiago de Compostela, Spain) and Spinworks (Univ. of Manitoba, Canada)

The processed NMR data is then exported for multivariate statistical analysis, including principal component analysis (PCA), projection to latent structures (PLS), orthogonal-PLS (OPLS) and support vector machine analysis (SVM).

Additional methods are currently under development. The software utilized by the lab includes SimcaP+ (Umetrics, Umea, Sweden) and Matalab (Mathworks, Natick, MA).

« Show less
NMR
Nuclear magnetic resonance spectroscopy
Price on request

The NMR technology requires minimal sample preparation on most biofluids.

NMR Database. We use the Chenomx NMR database in our analysis that allows us to get absolute quantitation on nearly 300 metabolites including, amino acids, organic acids, amines, nucleic acids, carbohydrates, drug related metabolites, etc.

NMR is... Show more »

The NMR technology requires minimal sample preparation on most biofluids.

NMR Database. We use the Chenomx NMR database in our analysis that allows us to get absolute quantitation on nearly 300 metabolites including, amino acids, organic acids, amines, nucleic acids, carbohydrates, drug related metabolites, etc.

NMR is an inherently fully quantitative technique and does not require authentic standards for quantitation.

absolute quantitation on nearly 300 metabolites including, amino acids, organic acids, amines, nucleic acids, carbohydrates, drug related metabolites, etc.

Multidimensional NMR. For unknown compounds we run multidimensional NMR experiments (e.g. gDQCOSY, gTOCSY, gHSQC, gHMBC, selective TOCSY, etc) which yield spectra containing a wealth structural information for the elucidation of novel & unknown metabolites.

« Show less
Mass Spectrometry
Price on request
Request a quote for more information about this service.
Spectroscopy
Price on request
Request a quote for more information about this service.
LC-MS
Liquid Chromatography-Coupled Mass Spectrometry
Price on request

We have a Sciex 5600 TripleTOF that can do untargeted metabolomics, but we use it for targeted metabolites and isotopologue quantification for use in flux analysis and drug quantification. It has two HPLCs attached, one with a C18 column and the other with a HILIC.

We have a Sciex 5600 TripleTOF that can do untargeted metabolomics, but we use it for targeted metabolites and isotopologue quantification for use in flux analysis and drug quantification. It has two HPLCs attached, one with a C18 column and the other with a HILIC.

« Show less
Omics
Price on request
Request a quote for more information about this service.
Data Analysis and Management
Price on request
Request a quote for more information about this service.
Biology
Price on request
Request a quote for more information about this service.
Imaging & Spectroscopy
Price on request
Request a quote for more information about this service.
Image Analysis
Price on request
Request a quote for more information about this service.
Liquid Chromatography Coupled Mass Spectrometry Methods
Price on request
Request a quote for more information about this service.
Metabolite Profiling
Price on request
Request a quote for more information about this service.
Pharmacology & Toxicology
Price on request
Request a quote for more information about this service.
Bioanalysis
Price on request
Request a quote for more information about this service.
Biomarkers
Price on request
Request a quote for more information about this service.
Computational & Statistical Analysis
Price on request
Request a quote for more information about this service.
Metabolomics
Price on request
Request a quote for more information about this service.
Ask A Question Find what you're looking for? If not, you can ask this lab a question:

UNC Metabolomics Laboratory has not received any ratings.

Be the first to endorse UNC Metabolomics Laboratory

Endorse this lab