For over 21 years, the UCSF/CFAR Core Immunology Lab (CIL) has been dedicated to providing immunology assays, expert consultation, and education to the UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.
Evaluation of cytokines and chemokines from plasma, serum, CSF and tissue culture supernatants by ELISA and multiplexed bead array
Flow cytometric functional assays, including NK cell function, antigen-specific CD4+ and CD8+ T cell cytokine expression, degranulation and proliferation
Immunophenotyping of whole blood, PBMC, MMC and cerebrospinal fluid for: NK, B and T cells percentages, and their subsets, including maturation, trafficking, senescence, activation, in vivo proliferation and chemokine receptor expression
Evaluation of T cell signaling by phosflow using monoclonal antibodies specific for phosphorylated proteins
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