1400874702716 aebcd941eba981d7ea884d0102d2a11c

UCL IQPath

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London, GB

About UCL IQPath

UCL IQPath (Institute of Neurology Queen Square Pathology) is a state of the art facility that performs histological and immunohistochemical techniques on research and diagnostic specimens. Our main expertise is mouse and human histology of the central nervous system, but we cut up, embed, section and stain... Show more »

UCL IQPath (Institute of Neurology Queen Square Pathology) is a state of the art facility that performs histological and immunohistochemical techniques on research and diagnostic specimens. Our main expertise is mouse and human histology of the central nervous system, but we cut up, embed, section and stain any other tissue.

We are specialised on paraffin sectioning and all our antibodies are optimised for formalin fixed, paraffin embedded material.

Our team can process large quantities (sectioning of up to 100 paraffin blocks per day) and we have the equipment to carry out 150 immunostainings per day. We are offering a large repertoire of antibodies for paraffin sections, (more than 100 antibodies optimised for human and more than 50 antibodies optimised for murine targets). We can also digitise slides, store the data and make them accessible via web browser.

In addition to histological techniques, we advise on histological analysis, in particular of the brain, and the spinal cord, on specific request. The facility is led by Professor Sebastian Brandner, who has expertise in human neuropathology and mouse phenotyping, with particular focus on developmental abnormalities, neuro-oncology and neurodegeneration.

Certifications: CPA registration (ISO 9001)

Relevant publications:
http://www.ncbi.nlm.nih.gov/pubmed/23887970
http://cancerres.aacrjournals.org/content/73/18/5834.long
http://www.ncbi.nlm.nih.gov/pubmed/24129059

Standard sample shipment requests:
- Safe packaging with adsorbent for all formalin samples
- Standard UK Mail packages for paraffin blocks

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Our Services (28)


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Data Storage

Starting at £0.20 per gigabyte

Digital Pathology data slides can be stored on our secure file server for remote viewing. The quoted price refers to the cost of monthly storage.

Digital Pathology data slides can be stored on our secure file server for remote viewing. The quoted price refers to the cost of monthly storage.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes Ventana VANTAGE

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Whole Slide Imaging/Digital Slide Scanning

Starting at $1.50 per slide

Digital scanning of histology slides (LEICA SCN400F), storage of the data on a secure cloud server (UCL-IoN) and off-site viewing in any web browser (Slidepath Digital Image Hub).
Scanning of fluorescent slides is possible but technically challenging.
If you prefer to take the digital slide files (*.scn format) off site, we... Show more »

Digital scanning of histology slides (LEICA SCN400F), storage of the data on a secure cloud server (UCL-IoN) and off-site viewing in any web browser (Slidepath Digital Image Hub).
Scanning of fluorescent slides is possible but technically challenging.
If you prefer to take the digital slide files (*.scn format) off site, we can transfer them via ftp or upload on a harddisk. Files are 0.5-3 GByte each. Offsite viewing is possible with a free LEICA client, but functionality is limited
The cost includes scanning and basic annotation.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes LEICA SCN400F Ventana VANTAGE UCL-IoN Show 6 more tags Show less

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H&E Staining

Hematoxylin and eosin staining
Starting at $0.50 per slide

Staining is done on an automated LEICA Autostainer for consistent results. Automated coverslipping is applied after the staining for consistent, high quality results.

Staining is done on an automated LEICA Autostainer for consistent results. Automated coverslipping is applied after the staining for consistent, high quality results.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes LEICA Autostainer Ventana VANTAGE

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Digital Pathology Image Analysis

Starting at $35.00 per hour

We can analyse whole digital scans of bright field or fluorescent slides with a digital image analysis software, Definiens Tissue Studio and Definiens Developer. We can scan your histology slide or you can provide any type of digital pathology scans or Laser Scanning confocal images. This software is ideal for detection and... Show more »

We can analyse whole digital scans of bright field or fluorescent slides with a digital image analysis software, Definiens Tissue Studio and Definiens Developer. We can scan your histology slide or you can provide any type of digital pathology scans or Laser Scanning confocal images. This software is ideal for detection and quantification of biomarkers in cells and tissues. We can analyse slides using predefined algorithms in Definines Tissue Studio or we can develop new algorithms using the Definines Developer Software. Please request a quote from us for further information.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes Ventana VANTAGE

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Immunohistochemistry (IHC)

Starting at $12.00 per slide

Our laboratory offers the entire histology pathway: tissue dissection, embedding, and preparation of
histological slides. Our stainings include tinctorial stains as well as immunohistochemistry and
immunofluorescence.
We have three Ventana Discovery available for your staining requirements. We are specialised in mouse and... Show more »

Our laboratory offers the entire histology pathway: tissue dissection, embedding, and preparation of
histological slides. Our stainings include tinctorial stains as well as immunohistochemistry and
immunofluorescence.
We have three Ventana Discovery available for your staining requirements. We are specialised in mouse and human tissues.
To establish a new antibody that is not yet established in our lab, we charge £150 for the optimisation, or offer this for free if more than 50 slides are ordered

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes Ventana VANTAGE

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Paraffin Embedding

Starting at $5.00 per sample

Standard processing and paraffin embedding in a LEICA TP300 Processor. Includes cutup ("grossing"), correct orientation according to the customers' needs, preparation and labelling of the wax block.

Standard processing and paraffin embedding in a LEICA TP300 Processor. Includes cutup ("grossing"), correct orientation according to the customers' needs, preparation and labelling of the wax block.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes LEICA TP300 Processor Ventana VANTAGE

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Paraffin Sectioning

Starting at £1.00 per slide

Our special expertise is the sectioning of central nervous tissue (Brain, spinal cord) but we can of course section any other tissue. The cost is for unstained sections. Sections are mounted on Superfrost plus glass slides and are labelled with a THERMO Label printer. 3D Barcodes optional if requested.

Our special expertise is the sectioning of central nervous tissue (Brain, spinal cord) but we can of course section any other tissue. The cost is for unstained sections. Sections are mounted on Superfrost plus glass slides and are labelled with a THERMO Label printer. 3D Barcodes optional if requested.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes Ventana VANTAGE

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Special Slide Staining

Starting at £5.00 per slide

We can stain common special stains, such as PAS, Luxol fast blue, Congo red, EvG etc.
INcluded dewax, stain, coverslip and QC.

We can stain common special stains, such as PAS, Luxol fast blue, Congo red, EvG etc.
INcluded dewax, stain, coverslip and QC.

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VENTANA Discovery XT VENTANA Discovery Ultra VENTANA NEXes Ventana VANTAGE

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Tissue Sectioning

Price on request
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Biospecimens

Price on request
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Clinical Laboratory Services

Price on request
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Clinical Research

Price on request
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Imaging & Spectroscopy

Price on request
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Cells and Tissues

Price on request
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Tissue Processing

Price on request
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Histological Staining

Price on request
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Biochemistry & Molecular Biology

Price on request
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Microscopy

Price on request
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Data Services

Price on request
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Image Analysis

Price on request
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Protein Expression Visualization

Price on request
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Common Histochemical Stains

Price on request
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Immunostaining

Price on request
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Protein Services

Price on request
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Tissue Embedding

Price on request
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Clinical and Anatomic Pathology

Price on request
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Biology

Price on request
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Computational Modeling

Price on request
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Jessica Broni

Histologist
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Francesca Launchbury

Histologist
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Angela Richard Loendt

Laboratory Manager and Lead Histologist
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Tamsin Wilkins

Histologist
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