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Translational Pathology Laboratory (TPL)

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Chapel Hill, North Carolina, US

About Translational Pathology Laboratory (TPL)

The Translational Pathology Laboratory (TPL) is a core facility in the UNC School of Medicine administered by the Lineberger Comprehensive Cancer Center and the Department of Pathology and Laboratory Medicine. We offer access to sophisticated digital pathology platforms and study design support to all UNC... Show more »

The Translational Pathology Laboratory (TPL) is a core facility in the UNC School of Medicine administered by the Lineberger Comprehensive Cancer Center and the Department of Pathology and Laboratory Medicine. We offer access to sophisticated digital pathology platforms and study design support to all UNC investigators to enhance translational research.

Recent Publications

  • Karginova O, Siegel MB, Van Swearingen AE, Deal AM, Adamo B, Sambade MJ, et al. Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer. Mol Cancer Ther. 2015;14(4):920-30. Epub 2015/04/01. doi: 10.1158/1535-7163.MCT-14-0474. PubMed PMID: 25824335; PubMed Central PMCID: PMC4394032.
  • Chang EHea. Palladin is Upregulated in Kidney Disease and Contributes to Epithelial Cell Migration After Injury. Sci Rep. 2015;5(7695).
  • Carson CC, Moschos SJ, Edmiston SN, Darr DB, Nikolaishvili-Feinberg N, Groben PA, et al. IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma. Clin Cancer Res. 2015;21(9):2167-76. Epub 2015/05/03. doi: 10.1158/1078-0432.CCR-14-1826. PubMed PMID: 25934889; PubMed Central PMCID: PMC4418029.
  • Zhou B, Damrauer JS, Bailey ST, Hadzic T, Jeong Y, Clark K, et al. Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal. J Clin Invest. 2014;124(2):553-63. Epub 2014/01/18. doi: 10.1172/JCI69804. PubMed PMID: 24435044; PubMed Central PMCID: PMC3904607.
  • Zhang L YH, Burk LM, Inscoe CR, Hadsell MJ, Chtcheprov P, Lee YZ, Lu J, Chang S, Zhou O. Image-guided microbeam irradiation to brain tumour bearing mice using a carbon nanotube x-ray source array. Phys Med Biol. 2014;59:1283-303. PubMed Central PMCID: PMCPMC4028041.
  • Wyss AB WM, Avery CL, Herring AH, Bensen JT, Barnholtz-Sloan JS, Funkhouser WK, Olshan AF. Single nucleotide polymorphisms in nucleotide excision repair genes, Cancer Treatment, and the Head and Neck Cancer Survival. Cancer Causes & Control 2014;25:437, 2014. PubMed Central PMCID: PMC PMC4096829.
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Our Services (23)


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Assay Development

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Immunofluorescence

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Automated Image Analysis

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Immunohistochemistry (IHC)

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Digital Pathology Services

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Aperio XT, FL and Versa, Visiopharm, Definiens

Aperio XT, FL and Versa, Visiopharm, Definiens

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Aperio Visiopharm

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Tissue Microarrays

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Tissue Sectioning

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Image Analysis

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Image Analysis Services

Image Analysis Services

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Data Services

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Data Analysis and Management Services

Data Analysis and Management Services

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Computational Modeling

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Computational & Statistical Analysis Services

Computational & Statistical Analysis Services

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Immunostaining

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Immunostaining Services

Immunostaining Services

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Clinical and Anatomic Pathology

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Clinical and Anatomic Pathology Services

Clinical and Anatomic Pathology Services

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Clinical Laboratory Services

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Clinical Laboratory Services

Clinical Laboratory Services

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Clinical Research

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Clinical Research Services

Clinical Research Services

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Protein Expression Visualization

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Protein Expression Visualization Services

Protein Expression Visualization Services

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Protein Services

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Protein Services

Protein Services

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Biochemistry & Molecular Biology

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Biochemistry & Molecular Biology Services

Biochemistry & Molecular Biology Services

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Tissue Processing

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Tissue Processing Services

Tissue Processing Services

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Biospecimens

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Biospecimens Services

Biospecimens Services

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Cells and Tissues

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Cells and Tissues Services

Cells and Tissues Services

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Biology

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Biology Services

Biology Services

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Imaging & Spectroscopy

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Imaging & Spectroscopy Services

Imaging & Spectroscopy Services

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Project Management

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Project Management & Consulting Services

Project Management & Consulting Services

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Nana Feinberg

Facility Director

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