Wmn1vomlszmnz7iquc0s toxikon logowithtag rgb

Toxikon Corporation

Bedford, Massachusetts, US

Toxikon is a leading preclinical contract research organization (CRO) providing in vivo, in vitro, and analytical testing services for the pharmaceutical, biotechnology, and medical device industries – helping those companies gain approval for their products quickly and bring them to market successfully.

We are proud to play a vital and singular role in the chain of events that move innovative therapies from concept, through research and development, into trials and approvals, through production and commercialization, and finally delivered to the consumer. We care about your products – and the life-changing outcomes they can offer – as much as you do.

With over 40 years of broad and deep experience in navigating the dynamic regulatory landscape, we have the expertise and technical skill to supply you with the results you need to gain approval for your products, demonstrating safety and efficacy.

Toxikon Corporation has not listed any services.

Medical Device Testing
Price on request

Toxikon provides full testing support for the ISO 10993 guidance.

With a strong foundation in toxicology and biocompatibility, our custom device testing capabilities include:
* ocular device and drug product development
* proof of concept studies
* surgical efficacy studies
* comprehensive biocompatibility analysis
*... Show more »

Toxikon provides full testing support for the ISO 10993 guidance.

With a strong foundation in toxicology and biocompatibility, our custom device testing capabilities include:
* ocular device and drug product development
* proof of concept studies
* surgical efficacy studies
* comprehensive biocompatibility analysis
* sterilization support
* reusable medical device cleaning validation
* combination product evaluations

« Show less
ISO 10993
Custom Ophthalmology Animal Models
Price on request

As a multidisciplinary contract research organization, Toxikon is focused on evaluating the safety and toxicity of biologics, pharmaceuticals and medical devices. One of Toxikon’s specialties is conducting studies focused on the treatment of ocular diseases. Our experienced study directors will provide you with the expertise in... Show more »

As a multidisciplinary contract research organization, Toxikon is focused on evaluating the safety and toxicity of biologics, pharmaceuticals and medical devices. One of Toxikon’s specialties is conducting studies focused on the treatment of ocular diseases. Our experienced study directors will provide you with the expertise in ophthalmology models and endpoints for your ocular drug program.

Ophthalmic Development Capabilities:

While our reputation has been built on our vast toxicology and chemistry experience,Toxikon’s Ocular Program capabilities include:

  • Intra-vitreal injections, stereotaxic surgery
  • Aesthesiometry, tonometry, pupilometry; and electroretinography (ERG)
  • Slit-Lamp exams and Draize and McDonald-Shadduck scoring systems Direct and indirect ophthalmoscopy
  • Anterior/posterior segment and fundus photography
  • Ocular tissue dissection, distribution and PK/PD/ADME
  • Retina/choroid flat-whole mounting, confocal microscopy, and RGC quantitation
  • Ocular histology/pathology and clinical support
  • Stereo and fluorescent microscopy
  • Optic nerve damage assessment
  • Specialized surgeries (e.g. episcleral vein injections to induce elevated IOP)

These studies in small and large animal models, include acute irritation, ocular distribution (PK/PD), acute and repeat dose toxicity, implantation, drug screening and drug efficacy. We can also customize studies for targeted therapeutics, such as dry eye and corneal wound healing, inflammation and uveitis, neovascularization and age-related macular degeneration, glaucoma and neuroprotection.

As part of our extensive custom research and testing portfolio for ophthalmic drug discovery, we offer a variety of preclinical services, including the screening of neuroprotective compounds and creation of animal models for glaucoma research. Our scientists are experts in the field, and their work is published widely. We invite you to speak with them at upcoming conferences and to see samples of their work.

« Show less
Rabbit
Mouse
Rat
Dog
Rodents
In vivo Bioavailability/Bioequivalence Studies
Price on request
Request a quote for more information about this service.
In vivo Pharmacology Studies
Price on request
Request a quote for more information about this service.
Toxicology
Price on request
Request a quote for more information about this service.
USP Water Testing
Price on request
Request a quote for more information about this service.
UV-VIS Spectroscopy
Price on request
Request a quote for more information about this service.
Trace Metal Analysis
Price on request
Request a quote for more information about this service.
Sterility Testing
Price on request
Request a quote for more information about this service.
Chemical Stability Testing
Price on request
Request a quote for more information about this service.
Product Stability Testing
Price on request
Request a quote for more information about this service.
Raw Material Testing
Price on request
Request a quote for more information about this service.
In vivo Drug Efficacy Testing
Price on request
Request a quote for more information about this service.
Photostability Studies
Price on request
Request a quote for more information about this service.
Preclinical Study Design
Price on request
Request a quote for more information about this service.
ADME/DMPK Studies
Drug Metabolism and Pharmacokinetics
Price on request
Request a quote for more information about this service.
Biocompatibility Testing
Price on request

The goal of in vivo testing medical devices is to determine the safety or biocompatibility of the device in a biological environment. Toxikon can design a study that is specific to determining the ability of a medical device to perform with an appropriate host response in a given application. Our In Vivo Department study... Show more »

The goal of in vivo testing medical devices is to determine the safety or biocompatibility of the device in a biological environment. Toxikon can design a study that is specific to determining the ability of a medical device to perform with an appropriate host response in a given application. Our In Vivo Department study directors will work closely with you to design biocompatibility assessments to measure the magnitude and duration of alterations in homeostatic mechanisms, favorable and adverse, in determining host response.

Some of the services for medical device development that Toxikon offers are:

  • Biocompatibility
  • Analytical and Bioanalytical Chemistry
  • Microbiology
  • Chronic, Genetic and Molecular Toxicology
  • Reproductive and Developmental Toxicology

Other tests: Sensitization, intracutaneous irritation, acute systemic toxicity, subchronic toxicity, implantation, hemocompatibility, and carcinogenicity.

« Show less
Radiotracers and Radiopharmaceuticals
Price on request
Request a quote for more information about this service.
Microbiology Testing
Price on request
Request a quote for more information about this service.
In vitro Metabolic Stability Assays
Price on request
Request a quote for more information about this service.
Material Testing Services
Price on request
Request a quote for more information about this service.
IND/NDA/BLA Submission
Investigational New Drug/New Drug Application Submission
Price on request
Request a quote for more information about this service.
Mass Spectrometry
Price on request
Request a quote for more information about this service.
HPLC
High Performance Liquid Chromatography
Price on request
Request a quote for more information about this service.
In vivo Immunotoxicity Testing
Price on request
Request a quote for more information about this service.
Rabbit
Mouse
Rat
Dog
Rodents
Immunobiology Services
Price on request
Request a quote for more information about this service.
Pharmaceutical Formulation
Price on request
Request a quote for more information about this service.
Extractable and Leachable Testing
Price on request
Request a quote for more information about this service.
Drug Development
Price on request
Request a quote for more information about this service.
Contract Research
Price on request
Request a quote for more information about this service.
Package and Container Testing
Price on request
Request a quote for more information about this service.
Gas Chromatography (GC)
Gas Chromatography
Price on request
Request a quote for more information about this service.
Chemical Analysis
Price on request
Request a quote for more information about this service.
Biological Testing
Price on request
Request a quote for more information about this service.
Bioanalytical Analysis LC/MS/MS
Price on request
Request a quote for more information about this service.
Analytical Validation
Price on request
Request a quote for more information about this service.
Analytical Method Development
Price on request
Request a quote for more information about this service.
Analytical Chemistry Services
Price on request
Request a quote for more information about this service.
Accelerated Stability Testing
Price on request
Request a quote for more information about this service.
Mutagenicity Testing
Price on request
Request a quote for more information about this service.
Maximum Tolerated Dose (MTD) Studies
Price on request
Request a quote for more information about this service.
Impurity Analysis
Price on request
Request a quote for more information about this service.
Animal Surgery
Price on request
Request a quote for more information about this service.
AH50 Assay
Price on request
Request a quote for more information about this service.
CH50 Assay
Price on request
Request a quote for more information about this service.
In vitro Hemolysis Assay
Price on request
Request a quote for more information about this service.
Antimicrobial Efficacy Testing
Price on request
Request a quote for more information about this service.
Agar Diffusion Testing
Price on request
Request a quote for more information about this service.
Guinea Pig Models
Price on request
Request a quote for more information about this service.
Athymic Nude-Foxn1nu Mouse Model
Price on request
Request a quote for more information about this service.
A/J Mouse Model
Price on request
Request a quote for more information about this service.
Rabbit Models
Price on request
Request a quote for more information about this service.
Compendial Testing
Price on request
Request a quote for more information about this service.
Ocular Inflammation Animal Models
Price on request
  • Experience performing both short term and long term ocular studies
  • Studies typically cover conjunctiva, cornea, lens, fundus, choroid, and optic nerve
  • Studies performed by in-house ophthalmologist with experience performing ocular implants

  • Ocular Examinations include:
    •Anterior segment of the eye•Slit-Lamp; Draizeand... Show more »

  • Experience performing both short term and long term ocular studies
  • Studies typically cover conjunctiva, cornea, lens, fundus, choroid, and optic nerve
  • Studies performed by in-house ophthalmologist with experience performing ocular implants

  • Ocular Examinations include:
    •Anterior segment of the eye•Slit-Lamp; Draizeand McDonald-Shadduckscoring systems
    •Posterior segment of eye
    •Direct & Indirect ophthalmoscopy

« Show less
Rabbit
Mouse
Rat
Dog
Tonovet
Tono-Pen
Glaucoma Animal Models
Price on request
Request a quote for more information about this service.
Corneal Dystrophy Animal Models
Price on request
Request a quote for more information about this service.
Dry Eye Animal Models
Price on request
Request a quote for more information about this service.
Macular Degeneration Animal Models
Price on request
Request a quote for more information about this service.
Diabetic Retinopathy Animal Models
Price on request
Request a quote for more information about this service.
In vivo Protein Binding Assays
Price on request
Request a quote for more information about this service.
Microbiology Assays
Price on request
Request a quote for more information about this service.
Cells and Tissues
Price on request
Request a quote for more information about this service.
Chromatography
Price on request
Request a quote for more information about this service.
In vitro Bioavailability/Bioequivalence Studies
Price on request
Request a quote for more information about this service.
Spectroscopy
Price on request
Request a quote for more information about this service.
Biospecimens
Price on request
Request a quote for more information about this service.
Water Quality Monitoring
Price on request
Request a quote for more information about this service.
Process Consulting
Price on request
Request a quote for more information about this service.
In vivo Toxicity Testing
Price on request
Request a quote for more information about this service.
Rabbit
Mouse
Rat
Dog
Rodents
Clinical Immunology Tests
Price on request
Request a quote for more information about this service.
Safety Pharmacology
Price on request
Request a quote for more information about this service.
Biomolecular Interaction Analysis
Price on request
Request a quote for more information about this service.
In vitro Disease Models
Price on request
Request a quote for more information about this service.
Model Organisms
Price on request
Request a quote for more information about this service.
Product Testing Services
Price on request
Request a quote for more information about this service.
In vivo PK/PD Studies
Price on request
Request a quote for more information about this service.
Clinical Imaging Services
Price on request
Request a quote for more information about this service.
Animal Models and Studies
Price on request
Request a quote for more information about this service.
Mouse Models
Price on request
Request a quote for more information about this service.
Liquid Chromatography
Price on request
Request a quote for more information about this service.
Clinical Research
Price on request

Sample Analysis

Sample Analysis

« Show less
Chemistry and Materials
Price on request
Request a quote for more information about this service.
Clinical Laboratory Services
Price on request
Request a quote for more information about this service.
Product Development, Testing, and Packaging
Price on request

Biocompatibility testing of materials and packaging.

Biocompatibility testing of materials and packaging.

« Show less
Microbiology
Price on request
Request a quote for more information about this service.
Cytotoxicity Assays
Price on request
Request a quote for more information about this service.
Animal Models of Disease
Price on request
Request a quote for more information about this service.
Packaging Services
Price on request
Request a quote for more information about this service.
Radiochemistry
Price on request
Request a quote for more information about this service.
Immunoassays
Price on request
Request a quote for more information about this service.
In vitro ADME/DMPK Studies
Price on request
Request a quote for more information about this service.
Spectrophotometry
Price on request
Request a quote for more information about this service.
Cell Culture Media and Reagents
Price on request
Request a quote for more information about this service.
Rodent Models
Price on request
Request a quote for more information about this service.
Bioanalysis
Price on request
Request a quote for more information about this service.
Antimicrobial Activity Testing
Price on request
Request a quote for more information about this service.
Formulation Services
Price on request
Request a quote for more information about this service.
Imaging & Spectroscopy
Price on request
Request a quote for more information about this service.
Medical Devices & Diagnostics
Price on request
Request a quote for more information about this service.
Drug Discovery & Development
Price on request
Request a quote for more information about this service.
Biology
Price on request
Request a quote for more information about this service.
Ophthalmology Animal Models
Price on request
Request a quote for more information about this service.
Bioanalytical Assays
Price on request
Request a quote for more information about this service.
Project and Process Management
Price on request
Request a quote for more information about this service.
Regulatory Affairs Services
Price on request
Request a quote for more information about this service.
Animal Physiology Analyses
Price on request
Request a quote for more information about this service.
Pharmacology & Toxicology
Price on request
Request a quote for more information about this service.
Mammalian Models
Price on request
Request a quote for more information about this service.
Toxicity Animal Model
Price on request
Request a quote for more information about this service.
Dog
Biochemistry & Molecular Biology
Price on request
Request a quote for more information about this service.
Experimental Design
Price on request
Request a quote for more information about this service.
Pharmacology
Price on request

Pharmacology Services

Pharmacology Services

« Show less
2018-07-18 02:29:17 +0800

Net Promoter Score of 8 received for Toxicology.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 8.

Be the first to endorse Toxikon Corporation

Endorse this lab