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Three Dimension Genomics, Inc.

5 Orders Completed
Carlsbad, California, US

About Three Dimension Genomics, Inc.

Three Dimension Genomics, Inc. is enabling next-generation drug development screens using high-throughput screening, cerebral organoids and single-cell transcriptomics.

We use our proprietary in vitro genetics platform in collaboration with drug industry partners to identify novel drug targets and... Show more »

Three Dimension Genomics, Inc. is enabling next-generation drug development screens using high-throughput screening, cerebral organoids and single-cell transcriptomics.

We use our proprietary in vitro genetics platform in collaboration with drug industry partners to identify novel drug targets and elucidate molecular mechanisms of action. We also collaborate with government partners to determine pathways of toxicity for thousands of environmental toxicants.

The power of this technology will provide you a competitive advantage over those using traditional cell culture methods and bulk RNA-sequencing by saving you time and money.

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Our Services (21)


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Organoids

Price on request

We specialize in the development of organoid models from ESC, iPSC and lineage restricted stem cells. Analysis methods focus on single cell technologies such as scRNAseq, high content imaging, and FACS analysis and sorting. We work with you to design the most appropriate experiment to fit your needs. Most of our studies have... Show more »

We specialize in the development of organoid models from ESC, iPSC and lineage restricted stem cells. Analysis methods focus on single cell technologies such as scRNAseq, high content imaging, and FACS analysis and sorting. We work with you to design the most appropriate experiment to fit your needs. Most of our studies have been with human and mouse cerebral organoids and we are adding other tissue organoid models. 

- Develop or establish organoid models from stem cell lines.  

- Conduct analysis of organoids across genetics, compound treatment, developmental stage, or combinations of the above. 

- Dissociate organoids and analyze at the single cell level.

- Identify cell types, determine transcriptomes, phenotypic and functional measures.

- Identify upregulated and downregulated genes/pathways to elucidate mechanism of action. 

 

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Human Mouse Psychiatry/Mental Health CNS/Neurology Pain Alzheimers Disease Drug Discovery Toxicology Show 8 more tags Show less

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Single Cell RNA-Seq

Price on request

We conduct single cell RNAseq and bulk RNAseq experiments from samples that you provide. We can also establish conventional cell based models with human or nonhuman mammalian cell lines and conduct RNAseq as readout. Other plate based readouts can be added as desired (e.g., alphaLISA assays, RTCA label free assays,... Show more »

We conduct single cell RNAseq and bulk RNAseq experiments from samples that you provide. We can also establish conventional cell based models with human or nonhuman mammalian cell lines and conduct RNAseq as readout. Other plate based readouts can be added as desired (e.g., alphaLISA assays, RTCA label free assays, immunohistology assays from single well/slide to high content imaging, MEA assays etc).

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10x Genomics Chromium System

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Transcriptomics Data Analysis

Price on request

We offer tailored bioinformatic analysis of your single cell or bulk transcriptomic data, which includes:

-Fastq demultiplexing, read alignments, UMI counting, data normalization, dimensionality reduction and clustering, pseudotime analysis, data visualization, identification of affected cell types, identification of... Show more »

We offer tailored bioinformatic analysis of your single cell or bulk transcriptomic data, which includes:

-Fastq demultiplexing, read alignments, UMI counting, data normalization, dimensionality reduction and clustering, pseudotime analysis, data visualization, identification of affected cell types, identification of up-regulated and down-regulated genes and pathways, and identification of master regulators and causal networks.

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Stem Cell Differentiation

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3D Cell Culture Models

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Toxicology

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Biology

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Computational Modeling

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Biostatistics & Bioinformatics

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Cells and Tissues

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Project Management

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RNA Sequencing

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Nucleic Acid Services

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Biochemistry & Molecular Biology

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Data Services

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RNA Services

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Pharmacology & Toxicology

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Drug Discovery

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Drug Discovery & Development

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Cell and Tissue Culture

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Mammalian Cell Culture

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Ted Choi

President and Chief Scientific Officer

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