The Solubility Company is a preclinical contract research organization (CRO) providing solubility measurement services based on the proprietary image-based SPA method.
Through the innovative combination of optics, fluidics, automation and intelligent digital pattern recognition algorithms, the SPA method measures the thermodynamic, apparent solubility and related physicochemical parameters of practically any solid sample, with a turnaround as low as 24h from receipt of sample.
Our service laboratory is based in Helsinki, Finland and is operated by a highly skilled team with more than 50 years of experience in pharmaceutical development, high-tech R&D and management.
We offer a range of solubility measurement services based on the proprietary SPA method:
- thermodynamic/apparent/intrinsic/native solubility
in buffer solutions, physiological solutions and organic solvents.
The measurement can be made fully blinded from around 100 micrograms of solid sample, without requiring information on the chemical structure of the compound.
We offer a range of solubility measurement services based on the proprietary SPA method:
- thermodynamic/apparent/intrinsic/native solubility
- logP/logD
- pKa
in buffer solutions, physiological solutions and organic solvents.
Individual measurements use only around 100 micrograms of solid sample and can be made fully blinded without requiring information on the chemical structure of the compound.
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