1397013017676 31c6622ffbaaaf241066ed7a581a1fd0

Synthetic Organic Chemistry Core

Galveston, Texas, US

The SOCC at UTMB-Galveston, TX is a federally subsidized lab, and as such we normally do not take on commercial projects. If you are a researcher working on a federally funded grant then of course we can help you.

The Synthetic Organic Chemistry Core (SOCC) at UTMB was established in 1998 to study and develop new methods and protocols for the synthesis of modified nucleosides representing known DNA damage, and for conversion of these nucleosides into phosphoramidites that can be conveniently and site-specifically incorporated into synthetic DNA sequences. The SOCC also develops methods for incorporating lesion sites into oligonucleotides via post-synthesis methods and protocols for purifying and analyzing these defined products.

The synthetic organic services provided have also been adapted and expanded over the past 10 years to accommodate a growing need for synthesis and purification of other small... Show more »

The SOCC at UTMB-Galveston, TX is a federally subsidized lab, and as such we normally do not take on commercial projects. If you are a researcher working on a federally funded grant then of course we can help you.

The Synthetic Organic Chemistry Core (SOCC) at UTMB was established in 1998 to study and develop new methods and protocols for the synthesis of modified nucleosides representing known DNA damage, and for conversion of these nucleosides into phosphoramidites that can be conveniently and site-specifically incorporated into synthetic DNA sequences. The SOCC also develops methods for incorporating lesion sites into oligonucleotides via post-synthesis methods and protocols for purifying and analyzing these defined products.

The synthetic organic services provided have also been adapted and expanded over the past 10 years to accommodate a growing need for synthesis and purification of other small molecules and bioconjugates that are of interest to biomedical and environmental health researchers at UTMB and elsewhere. This area of synthesis continues to grow rapidly with expansion of the Integrative Health Sciences Facility Core's Exposure Assessment and Biomarker Development Facility and its focus on assay development for monitoring exposure and disease.

Members:
- Richard P. Hodge, Ph.D.
Director, Synthetic Organic Chemistry Service Core, Scientist, Sealy Center for Environmental Health & Medicine
- Linda C. Hackfeld, M.S.
Member, Synthetic Organic Chemistry Service Core, Research Associate III, Sealy Center for Environmental Health & Medicine
- Omar Guerra, B.S.
Member, Synthetic Organic Chemistry Service Core, Research Associate I, Sealy Center for Environmental Health & Medicine

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Aptamer Conjugation
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The SOCC at UTMB-Galveston, TX is a federally subsidized lab, and as such we normally do not take on commercial projects. If you are a researcher working on a federally funded grant then of course we can help you.

Organic synthesis for a bioconjugate made with a DNA strand and hydrolase-specific target particle.... Show more »

The SOCC at UTMB-Galveston, TX is a federally subsidized lab, and as such we normally do not take on commercial projects. If you are a researcher working on a federally funded grant then of course we can help you.

Organic synthesis for a bioconjugate made with a DNA strand and hydrolase-specific target particle.

Researcher should provide the target spec and recommended starting materials.

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Biology
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Aptamers
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DNA Synthesis and Probe Development
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DNA
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Biochemistry & Molecular Biology
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Nucleic Acid Services
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