Synthego’s Full Stack Genome Engineering portfolio includes design and analysis software, synthetic RNA kits, and gene editing services for CRISPR-based research. Our vision is to bring precision and automation to genome engineering, enabling rapid and cost-effective research with consistent results for every scientist.
CRISPRevolution Custom RNA is tailored to how you want to do your research: Cpf1, C2c2, S. aureus Cas9, CRISPRi or any novel nuclease. Or to alter the secondary structure of your tracrRNA.
CRISPRevolution Custom RNA
Tell us the sequence you want and we’ll make you the highest quality RNA – Synthego’s CRISPRevolution Custom RNA is a fully custom target sequence guide RNA product for CRISPR genome editing.
Custom RNA 50
Custom RNA 50 is perfect for designing short guide RNAs for nucleases that don’t require long sequences, such as Cpf1. You can use it to design your own Cas9 crRNA and custom 3′ linker to a tracrRNA.
Custom RNA 75
Custom RNA 75 is perfect for designing guide RNAs for nucleases that don’t require guides as long as S. pyogenes Cas9. You can use it to design your own Cas9 tracrRNA and custom 5′ linker to a crRNA.
Custom RNA 100
Custom RNA 100 is perfect for designing full length sgRNA (100-mer) for CRISPR at a practical scale and price point. You can custom design your entire sgRNA sequence from 76-100 nucleotides.
Need Chemical Modifications?
For a chemically modified version of our Custom RNA, we offer 2’-O-methyl and 3’ phosphorothioate internucleotide linkages at the first three 5’ and 3’ terminal RNA residues. Chemically modified sequences can provide additional additional RNA stability with improvements in editing efficiency for particular cell types (e.g. human stem cells) and genomic targets that prove otherwise challenging to edit.
CRISPRevolution Custom RNA Specifications
"Super smooth and nice experience."
"They were timely and kept us informed at every step of the process. The product received was as expected with no issues."
"My order for gRNAs was completed a week before the scheduled ship date! Very fast turn-around time. I would recommend Synthego to others."
"The service is great and gRNA quality is good."
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