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Syneos Health (INC Research + InVentiv Health)

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Princeton, New Jersey, US

About Syneos Health (INC Research + InVentiv Health)

The coming together of INC Research and inVentiv Health as one global company, called Syneos Health™, has created the industry’s only true end-to-end solution. This one entity combines world-renowned clinical research and commercialization capabilities with today’s most advanced science, business and data... Show more »

The coming together of INC Research and inVentiv Health as one global company, called Syneos Health™, has created the industry’s only true end-to-end solution. This one entity combines world-renowned clinical research and commercialization capabilities with today’s most advanced science, business and data technologies to make real advances possible. We help you improve performance, reduce risk and expedite delivery of healthcare innovation to patients worldwide.

Our bioanalytical services center around delivering on our commitment to meet project schedules without compromising quality and compliance. Because we recognize your need for fast turnaround, method development and proof-of-concept can typically be performed within a few days, enabling quick go/no-go decisions.

We combine our significant experience with small and large molecules, peptides, immunochemistry, LC/MS/MS, HRMS, GC/MS/MS, ICP-MS and blend innovative science with efficient, validated processes.

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Our Services (180)


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In vivo Bioavailability/Bioequivalence Studies

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Bioanalysis

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We take the “full capability” approach to bioanalytical services, regardless of your project size. Through our GLP-compliant laboratories, an extensive list of validated assays, custom assay services, knowledgeable scientists and skilled technicians, we provide bioanalytical services at all stages of drug development.

Then, we... Show more »

We take the “full capability” approach to bioanalytical services, regardless of your project size. Through our GLP-compliant laboratories, an extensive list of validated assays, custom assay services, knowledgeable scientists and skilled technicians, we provide bioanalytical services at all stages of drug development.

Then, we combine our significant experience with small and large molecules, peptides, immunochemistry, LC/MS/MS, HRMS, GC/MS/MS, ICP-MS and blend innovative science with efficient, validated processes.

In-House Expertise and Modern Instrumentation for Rapid Turnaround Times

We have a long history of partnering with biopharmaceutical companies for in vivo, non-regulated preclinical bioanalysis of plasma and tissue samples. We have in-house expertise and access to a sophisticated array of modern instrumentation that enables rapid turnaround times.

Customers look to us to develop bioanalytical methods and assay samples generated in a non-GLP, high-throughput environment and to report sample concentrations with preliminary pharmacokinetics (PK) using WinNonlin® or Watson LIMS.

We offer HRMS-based methods, as well as traditional multiple reaction monitoring (MRM) assays using ultra-performance liquid-chromatography (UPLC) triple quadrupole LC/MS/MS analysis for PK work. We also offer specialized expertise in tissue analysis to support drug distribution studies, proteins, peptides, ADCs and nucleotides.

Our process is standardized around a robotics platform, which allows for improved precision, better reproducibility and fewer errors. We offer protein binding, bioavailability, early toxicology and method qualification services for the target compound, as well as its metabolites.

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Mass Spectrometry Method Development

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We offer custom method development, assay validation and sample analysis using state-of-the-art LC/MS/MS and immunochemistry assays and a team of detail-oriented scientists. Our staff has developed LC/MS/MS methods including routinely quantifying levels below one pg/mL.

We have methods for multiple analytes, metabolites,... Show more »

We offer custom method development, assay validation and sample analysis using state-of-the-art LC/MS/MS and immunochemistry assays and a team of detail-oriented scientists. Our staff has developed LC/MS/MS methods including routinely quantifying levels below one pg/mL.

We have methods for multiple analytes, metabolites, prodrugs and light- and temperature-sensitive compounds. Standard timelines for validation is around 5–10 days.

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Ligand Binding Assays

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We provide a growing menu of standard and custom assays optimized for the quantitation of multiple analytes (proteins) in serum, EDTA and heparin, as well as sodium citrate plasma, culture supernatant and other sample types.

Our immunoassay capabilities include single analytes and multiplexing. Services include development,... Show more »

We provide a growing menu of standard and custom assays optimized for the quantitation of multiple analytes (proteins) in serum, EDTA and heparin, as well as sodium citrate plasma, culture supernatant and other sample types.

Our immunoassay capabilities include single analytes and multiplexing. Services include development, optimization and validation of proprietary assays, transfer and validation of existing assays and validation of commercially available kits.

Significant experience in the development and validation of immunoassays for large molecules and biomarkers gives our clinical scientists special insight into the development of bioanalytical technologies. Work performed in our GLP-compliant immunochemistry facilities includes proprietary and non-proprietary pharmacokinetic and immunogenicity assays, as well as a wide range of cell-based and enzymatic assays.

By rapidly providing specialized immunogenicity testing for the presence of antibodies to biologic and biosimilar products, we can help move your large molecule development programs forward quickly and smoothly.

Our bioanalytical technologies and experience allows applications of a variety of immunoassay platforms, including: electrochemiluminescence (ECL), ELISA, fluorescence, luminescence and radioimmunoassays.

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Biomarkers

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We provide mass spectrometry-based and immunochemical analyses for the development, validation and measurement of biomarkers, including targeted and non-targeted biochemical and protein profiling. Our methods ensure precise, accurate measurement of biomarkers for therapeutic disease endpoints for infectious and autoimmune... Show more »

We provide mass spectrometry-based and immunochemical analyses for the development, validation and measurement of biomarkers, including targeted and non-targeted biochemical and protein profiling. Our methods ensure precise, accurate measurement of biomarkers for therapeutic disease endpoints for infectious and autoimmune diseases, cardiovascular risk, and blood components including hormones, cytokines, chemokines and acute-phase reactants.

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ICP-MS

Inductively Coupled Plasma Mass Spectrometry
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We offer ICP-MS to support (but not limited to) oncology trials. In the past decade, the advances in oncology medication, pain relief, chemotherapy or other therapy has dramatically changed the way cancer is diagnosed and treated.

Carboplatin and cisplatin are chemotherapy medications used to treat a number of forms of cancer.... Show more »

We offer ICP-MS to support (but not limited to) oncology trials. In the past decade, the advances in oncology medication, pain relief, chemotherapy or other therapy has dramatically changed the way cancer is diagnosed and treated.

Carboplatin and cisplatin are chemotherapy medications used to treat a number of forms of cancer. These compounds contain the element platinum that can be analyzed using the inductively-coupled plasma mass spectrometry or ICP-MS.

This instrument is designed for the analysis of natural elements such as platinum, iron, sodium, lithium and potassium. The diluted sample extracts are introduced in an argon plasma torch to be nebulized and ions are directed towards the quadrupole filer of the mass spectrometry detector by a set of lenses.

We have extended our expertise throughout the years and have validated several assays for the analysis of elements such as platinum, iron, sodium, potassium, zinc, lithium, strontium and bismuth. We have recently developed a combo assay for the measurement of magnesium, calcium and phosphorus in human serum and urine.

These methods are validated as per the most recent regulatory guidelines for bioanalytical method validations. Most of them were used successfully for study sample analyses. Other areas of interest include biomarkers (Na, K, Mg, Ca, Fe, PO4) and metal-based drugs (Li, K, SR, Bi, Zn, Pt).

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Clinical PK/PD Studies

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Immunogenicity & PK (including co-med analysis)

Immunogenicity & PK (including co-med analysis)

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Health Economic Modeling

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In vitro Immunogenicity Assays

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In vivo Immunogenicity Assays

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Immunoassays Toxicology

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In vitro Immunotoxicity Testing

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Toxicology

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Clindamycin Bioanalytical Assay

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Clavulanic Acid Bioanalytical Assay

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Clarithromycin Bioanalytical Assay

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Citalopram Bioanalytical Assay

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Cisplatin Bioanalytical Assay

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Cisapride/Norcisapride Bioanalytical Assay

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Ciprofloxacin Bioanalytical Assay

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Ciprofibrate Bioanalytical Assay

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Cinacalcet Bioanalytical Assay

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Drug Discovery & Development

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Custom Cell-Based Assay Development

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In vivo Toxicity Testing

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Cilostazol Bioanalytical Assay

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Biomolecular Interaction Analysis

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Biomolecular Interaction Analysis Services

Biomolecular Interaction Analysis Services

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Cell Culture Consulting

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Assay Development Consulting

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Ciclopirox Bioanalytical Assay

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Cholecalciferol Bioanalytical Assay

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Chlorpheniramine Bioanalytical Assay

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Chlormadinone Acetate/3-Hydroxy Chlormadinone Acetate Bioanalytical Assay

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Cetirizine Bioanalytical Assay

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Cephalexin Bioanalytical Assay

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Celecoxib Bioanalytical Assay

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Cefuroxime Bioanalytical Assay

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Cefprozil (Z)-Isomer and Cefprozil (E)-Isomer Bioanalytical Assay

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Cefpodoxime Bioanalytical Assay

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Cefixime Bioanalytical Assay

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Cefdinir Bioanalytical Assay

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Cefatrizine Bioanalytical Assay

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Cefadroxil Bioanalytical Assay

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Cefaclor Bioanalytical Assay

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Carvedilol/4-Hydroxyphenylcarvedilol Bioanalytical Assay

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Environmental Health and Safety Consulting

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Carisoprodol/Meprobamate Bioanalytical Assay

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Cell-Based Assays

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Carboplatin Bioanalytical Assay

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Carbamazepine Bioanalytical Assay

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Clinical Sample Analysis

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Captopril Bioanalytical Assay

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Capecitabine Bioanalytical Assay

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Formulation Services

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Candesartan Bioanalytical Assay

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In vitro Bioavailability/Bioequivalence Studies

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Calcitriol Bioanalytical Assay

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Cabergoline Bioanalytical Assay

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Process Consulting

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Butorphanol Bioanalytical Assay

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Bupropion, Hydroxybupropion, Erythrohydroxybupropion, Threohydroxybupropion Bioanalytical Assay

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Biostatistics & Bioinformatics

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Real-World Evidence (RWE) Studies

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Buprenorphine/Norbuprenorphine Bioanalytical Assay

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Safety Training

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Observational Research/ Non-Interventional Studies

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Bupivacaine Bioanalytical Assay

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Buflomedil Bioanalytical Assay

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Budesonide Bioanalytical Assay

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Phase I Clinical Trials

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Immunology Oncology Hematology CNS/Neurology Cardiovascular Women's Health and Prenatal Care Gastroenterology Infectious Disease Ophthalmology Respiratory Metabolism and Endocrinology Show 11 more tags Show less

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In vivo Immunotoxicity Testing

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Brompheniramine Bioanalytical Assay

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Clinical Trial Site Selection

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Bromide Bioanalytical Assay

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Regulatory Affairs Consulting

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Bosentan Bioanalytical Assay

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In vitro Toxicity Testing

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Bivalirudin Bioanalytical Assay

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Quality Assurance

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Bisoprolol Bioanalytical Assay

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Contract Services Directory

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Bismuth Bioanalytical Assay

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In vivo Pharmacology Studies

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Bicalutamide Bioanalytical Assay

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Biochemistry & Molecular Biology

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Benserazide Bioanalytical Assay

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Marketing, Communication & Graphic Design Services

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
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Benazeprilat Bioanalytical Assay

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Computer Science, Software Development, and IT Services

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Pharmacogenomics/Pharmacogenetics

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Bazedoxifene Bioanalytical Assay

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Validation, Services

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Label Printing

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Biochemical Assay Kits

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Biology

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Interactive Voice Response (IVR)/Interactive Web Response (IWR) System Development

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Balsalazide Bioanalytical Assay

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Clinical Validation of Diagnosis

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Data Collection

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Baclofen Bioanalytical Assay

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Staffing Services

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Patient Recruitment

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Azithromycin Bioanalytical Assay

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Product Development, Testing, and Packaging

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R&D Services

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IND/NDA/BLA Submission

Investigational New Drug/New Drug Application Submission
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Avonex Bioanalytical Assay

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Toxicology

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GMP Auditing

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Gene Therapy Development

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Packaging Services

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Deferasirox Bioanalytical Assay

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In vivo Drug Efficacy Testing

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GLP Auditing

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Daunorubicin/Daunorubicinol Bioanalytical Assay

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Other Mass Spectrometry Methods

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Other Mass Spectrometry Methods Services

Other Mass Spectrometry Methods Services

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Clinical Supply Chain Management and Logistics

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Data Services

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Dasatinib Bioanalytical Assay

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Mass Spectrometry

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Mass Spectrometry Services

Mass Spectrometry Services

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Database Systems

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Consulting

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Phase IV Clinical Trials

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Feasibility Studies

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Cyclosporin A Bioanalytical Assay

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Colchicine Bioanalytical Assay

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Clinical Trials, Consulting, and Management

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Phase III Clinical Trials

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Darifenacin Bioanalytical Assay

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Spectroscopy

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Spectroscopy Services

Spectroscopy Services

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Chemistry, Manufacturing and Controls (CMC)

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Phase II Clinical Trials

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Bioanalytical Assays

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Cortisol Bioanalytical Assay

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Codeine Bioanalytical Assay

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Clinical Data Collection, Analysis and Management

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Clinical Electronic Data Capture (EDC)

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Clinical Trial Management

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Dapsone Bioanalytical Assay

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Cocaine/Benzoylecgonine Bioanalytical Assay

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Computational Modeling

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Business Development Consulting

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Cells and Tissues

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Product Quality Control

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Clozapine/N-Desmethylclozapine Bioanalytical Assay

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Drug Development

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Clinical Trial Monitoring

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Clinical Research

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Dabigatran Bioanalytical Assay

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Cloxacillin Bioanalytical Assay

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Imaging & Spectroscopy

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Imaging & Spectroscopy Services

Imaging & Spectroscopy Services

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Biostatistical Analysis

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Clinical Validation Services

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Data Management

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In vivo PK/PD Studies

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Contract Research

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Project Management

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D-Threo-Methylphenidate Bioanalytical Assay

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Biopharmaceutical Development

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Clonazepam Bioanalytical Assay

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Biochemical Assays

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Clinical Ancillary and Sample Services

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Clopidogrel Bioanalytical Assay

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Biometrics

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Cytarabine/ARA-U Bioanalytical Assay

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Pharmacology & Toxicology

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Clonidine Bioanalytical Assay

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Clomiphene Cis (Z) and Trans (E) Isomers Bioanalytical Assay

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Specialized Cell-Based Assays

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Educational Services

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Auditing and Compliance Support

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Equipment

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Cyproterone Acetate Bioanalytical Assay

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Cell and Tissue Culture

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Biological Testing

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Immunoassays

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Statistical Analysis

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Regulatory Affairs Services

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Clinical Drug Management

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Epidemiology, Healthcare, and Post-Authorization Studies

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Pharmacology

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Pharmacology Services

Pharmacology Services

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Danielle Lachance

Senior Director, Business Development

Syneos Health (INC Research + InVentiv Health) has not received any reviews.

Syneos Health (INC Research + InVentiv Health) has not received any endorsements.