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Structured Immunity

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South Bend, Indiana, US

About Structured Immunity

Structured Immunity’s mission is to improve the safety and efficacy of T cell receptor based therapies.

Founded in 2017, Structured Immunity provides global expertise in structural immunology and the most advanced structure based TCR optimization platform available today.

Armed with this platform technology, Structured Immunity aims to serve the many ground-breaking biopharmaceutical companies in the industry, supporting the therapeutic development process by offering a suite of industry leading solutions.

Diversity Certificates

Small business

Our Services (6)


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Structural Biology

Price on request

Leading structural biology services for T cell receptors and other immunological proteins used in cell and bispecific therapies. Services range from X-ray crystallography, structure determination, protein design/engineering, antigen specificity screens, and biophysical analyses.


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TCR Screening and Validation

Price on request

Identify structurally compatible TCR peptide antigens, with little to no sequence similarity to the target peptide.


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X-ray Crystallography

Price on request

Crystallize a TCR alone or in complex with peptide/MHC antigen


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Structure Determination

Price on request

TCR structure determination


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Protein Engineering/Directed Evolution

Price on request

Using structure-based designs, optimize a TCR for affinity, specificity, and efficacy.


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Protein Biophysical Characterization

Price on request

Characterize TCR and peptide/MHC stability, affinity, and other thermodynamic properties.


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