Accelerating a new wave of medicines in cell therapy by revolutionizing the differentiation process. Differentiation is a fundamental biological process that is central to human life and the development of many biomedical applications. StemCellerant's patented technology is based on the discovery by its founders that allow stem cells to be directly differentiated to usable cell types. This stem-to-terminal differentiation is called accelerated differentiation. Previously, to generate usable cells from stem cells, one had to recapitulate many of the normal developmental steps to get to each cell, leading to a very lengthy and often ineffective process. StemCellerant avoids these problems by bypassing many of the intermediate stages of differentiation to generate a much safer and effective result. Combined with the Nobel-prize winning discovery of Shinya Yamanaka on dedifferentiation/reprogramming to induced pluripotent stem cells (iPSCs), StemCellerant's technology provides a way to develop next generation stem cell therapies and drugs that will be the future for patients.
Screening services for small molecules, gene therapies, ASOs, and other therapeutics on human iPSC-derived cells.
StemCellerant provides a custom service for differentiating pluripotent hiPS cells to functional terminally differentiated cell types using its accelerated differentiation technology, which speeds up pluripotent stem cell differentiation from weeks to several days. These cells can be used for therapy, drug discovery, disease modeling, and basic research.
- Higher quality (more physiological and closer to primary cells)
- Extremely rapid (3-5 day differentiation vs weeks/months elsewhere)
- High purity (up to >95%)
- Validated function and gene expression
- Can be scaled up to large quantities (e.g. for proteomics)
- Cells can be saved
- Highly robust and reproducible across users and cell lines
Cells differentiated from generic iPS cells: StemCellerant can also provide cells already differentiated from a generic human iPS line.
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