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SignaGen Laboratories

Rockville, Maryland, US

SignaGen Laboratories is a fast growing bio-reagents manufacturer founded by several ambitious bench scientists in 2007.

From 1st day of its creation, SignaGen has been arming to become the leader in developing and manufacturing gene delivery tools for the research community of US and beyond with logical prices. For chemical gene delivery tools, we have successfully developed and launched three categories DNA/siRNA transfection reagents for both in vitro and in vivo applications. For viral gene delivery vectors, we have developed Ad·MAX™ production system and AAV·HT™ packaging system for maximum recombinant adenovirus and AAV production.

SignaGen has been striving to offer the best gene delivery solutions with most affordable pricing. So far there are >1600 scientific papers citing our products and services.

SignaGen Laboratories, A Gene Delivery Company --------- "Your One Stop Gene Delivery Solution Chemical and Viral..."

SignaGen Laboratories has not listed any services.

AAV Production
Adeno-associated virus (AAV) production
Price on request

1). >150 pre-made rAAVs in stock.
2). rAAV Production Full Service, Large Scale
3). rAAV Production Full Service, Medium Scale
4). rAAV Production Full Service, Pilot Scale
5). rAAV Packaging Service, Large Scale
6). rAAV Packaging Service, Medium Scale
7). rAAV Packaging Service, Pilot Scale

1). >150 pre-made rAAVs in stock.
2). rAAV Production Full Service, Large Scale
3). rAAV Production Full Service, Medium Scale
4). rAAV Production Full Service, Pilot Scale
5). rAAV Packaging Service, Large Scale
6). rAAV Packaging Service, Medium Scale
7). rAAV Packaging Service, Pilot Scale

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Adenovirus production
Price on request

1). >400 Pre-made adenovirus in stock.
2). Adenovirus Production Full Service, Medium Scale
3). Adenovirus Production Full Service, Large Scale
4). Adenovirus Production Full Service, Pilot Scale
5). Adenovirus Amplification Service, Medium Scale
6). Adenovirus Amplification Service, Large Scale

1). >400 Pre-made adenovirus in stock.
2). Adenovirus Production Full Service, Medium Scale
3). Adenovirus Production Full Service, Large Scale
4). Adenovirus Production Full Service, Pilot Scale
5). Adenovirus Amplification Service, Medium Scale
6). Adenovirus Amplification Service, Large Scale

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AAV Production
Adeno-associated virus (AAV) production
Price on request

Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may... Show more »

Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell.

With our proprietary genetically engineered AAV·HT™ packaging cell, we are offering custom rAAV vector production services (conventional single stranded or double-stranded also known as self-complementary**) listed as follows to fit your different research needs.

Catalog # Service Items Final Deliverable (VG*) rAAV Purity Lead Time
SL100801 rAAV Production, Full Service, Large Scale >1E+13 VG (1.0 ml at >1E+13 VG/ml) In Vivo Grade 3~4 weeks
SL100861 rAAV Production, Full Service, Medium Scale >2E+12 VG (0.2 ml at >1E+13 VG/ml) In Vivo Grade 3~4 weeks
SL100865 rAAV Production, Full Service, Pilot Scale >1E+12 VG (0.1 ml at >1E+13 VG/ml) In Vivo Grade 3~4 weeks
SL100862 rAAV Packaging Service, Large Scale >1E+13 VG (1.0 ml at >1E+13 VG/ml) In Vivo Grade 1~2 weeks
SL100863 rAAV Packaging Service, Medium Scale >2E+12 VG (0.2 ml at >1E+13 VG/ml) In Vivo Grade 1~2 weeks

Large AAV cis vector collection offers tremendous flexibility for choosing a specific promoter and reporter.

Single promoter rAAV cis vector

Promoter:

Promoterless
CMV
CAG
H1
U6
Synapsin
UBC
EF1α
ALB(1.4)
ApoE/AAT1
CaMKII
ELA1
Enh358MCK
cTNT
GFAP
MBP
SST
TBG
αMHC
hRPE
mIP1
tMCK

Dual promoter rAAV cis vector

Promoter 1 Promoter 2 Reporter
Promoterless CMV eGFP
CMV CAG RFP
CAG H1 mRFP
H1 U6 mCherry
U6 Synapsin tdTOMATO
Synapsin UBC TurboGFP
UBC EF1α eYFP
EF1α CaMKII Venus
ALB(1.4) cTNT Luc
ApoE/AAT1 GFAP LacZ
CaMKII
ELA1
Enh358MCK
cTNT
GFAP
MBP
SST
TBG
αMHC
hRPE
mIP1
tMCK

With our proprietary genetically engineered AAV·HT™ packaging cell and a modified rAAV cis vector, the rAAV yield is easy to reach super high level--------total 1E+15 VG. For super high level rAAV production up to 1E+15 VG total , please contact us to request a quote.

  • Final viral yield may depend on the nature of transgene.
    ** Some terms may apply for custom double stranded or self-complementary rAAV production.
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Virus production
Price on request
Request a quote for more information about this service.
Microbiology, Virology, and Parasitology
Price on request
Request a quote for more information about this service.
Viral Production and Assays
Price on request
Request a quote for more information about this service.
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2016-12-09 11:09:44 -0800

Net Promoter Score of 10 received for AAV Production.

Additional Ratings: satisfaction with deliverable: 10, satisfaction with timeliness: 10.
2016-10-20 16:30:29 -0700

Net Promoter Score of 9 received for AAV Production.

Additional Ratings: satisfaction with deliverable: 9, satisfaction with timeliness: 8.

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