SignaGen Laboratories is a fast growing bio-reagents manufacturer founded by several ambitious bench scientists in 2008.
From 1st day of its creation, SignaGen has been arming to become the leader in developing and manufacturing gene delivery tools for the research community of US and beyond with logical prices. For chemical gene delivery tools, we have successfully developed and launched three categories DNA/siRNA transfection reagents for both in vitro and in vivo applications. For viral gene delivery vectors, we have developed Ad·MAX™ production system and AAV·HT™ packaging system for maximum recombinant adenovirus and AAV production.
SignaGen has been striving to offer the best gene delivery solutions with most affordable pricing. So far there are >3800 scientific papers citing our products and services.
SignaGen Laboratories, A Gene Delivery Company --------- "Your One Stop Gene Delivery Solution Chemical and Viral..."
1). >150 pre-made rAAVs in stock.
2). rAAV Production Full Service, Large Scale
3). rAAV Production Full Service, Medium Scale
4). rAAV Production Full Service, Pilot Scale
5). rAAV Packaging Service, Large Scale
6). rAAV Packaging Service, Medium Scale
7). rAAV Packaging Service, Pilot Scale
1). >400 Pre-made adenovirus in stock.
2). Adenovirus Production Full Service, Medium Scale
3). Adenovirus Production Full Service, Large Scale
4). Adenovirus Production Full Service, Pilot Scale
5). Adenovirus Amplification Service, Medium Scale
6). Adenovirus Amplification Service, Large Scale
Adeno-associated virus (AAV) is a small (20 nm in diameters) replication-defective, nonenveloped virus, which infects humans and some other primate species. AAV is not currently known to cause disease and consequently the virus causes a very mild immune response. AAV can infect both dividing and non-dividing cells and may incorporate its genome into that of the host cell.
With our proprietary genetically engineered AAV·HT™ packaging cell, we are offering custom rAAV vector production services (conventional single stranded or double-stranded also known as self-complementary**) listed as follows to fit your different research needs.
|Catalog #||Service Items||Final Deliverable (VG*)||rAAV Purity||Lead Time|
|SL100801||rAAV Production, Full Service, Large Scale||>1E+13 VG (1.0 ml at >1E+13 VG/ml)||In Vivo Grade||3~4 weeks|
|SL100861||rAAV Production, Full Service, Medium Scale||>2E+12 VG (0.2 ml at >1E+13 VG/ml)||In Vivo Grade||3~4 weeks|
|SL100865||rAAV Production, Full Service, Pilot Scale||>1E+12 VG (0.1 ml at >1E+13 VG/ml)||In Vivo Grade||3~4 weeks|
|SL100862||rAAV Packaging Service, Large Scale||>1E+13 VG (1.0 ml at >1E+13 VG/ml)||In Vivo Grade||1~2 weeks|
|SL100863||rAAV Packaging Service, Medium Scale||>2E+12 VG (0.2 ml at >1E+13 VG/ml)||In Vivo Grade||1~2 weeks|
Large AAV cis vector collection offers tremendous flexibility for choosing a specific promoter and reporter.
Single promoter rAAV cis vector
Dual promoter rAAV cis vector
|Promoter 1||Promoter 2||Reporter|
CMV | CAG | RFP CAG | H1 | mRFP H1 | U6 | mCherry U6 | Synapsin | tdTOMATO Synapsin | UBC | TurboGFP UBC | EF1α | eYFP EF1α | CaMKII | Venus ALB(1.4) | cTNT | Luc ApoE/AAT1 | GFAP | LacZ CaMKII | | ELA1 | | Enh358MCK | | cTNT | | GFAP | | MBP | | SST | | TBG | | αMHC | | hRPE | | mIP1 | | tMCK | |
With our proprietary genetically engineered AAV·HT™ packaging cell and a modified rAAV cis vector, the rAAV yield is easy to reach super high level--------total 1E+15 VG. For super high level rAAV production up to 1E+15 VG total , please contact us to request a quote.
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