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Shantani

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Pune, Maharashtra, IN

About Shantani

Shantani is a privately-held biotechnology company based in Pune, India. Our chemical-proteomics technology identifies & validates drug targets; thus de-risking molecules and supporting crucial GO / NO-GO decisions throughout the drug discovery process.

Our proprietary work-flow provides comprehensive... Show more »

Shantani is a privately-held biotechnology company based in Pune, India. Our chemical-proteomics technology identifies & validates drug targets; thus de-risking molecules and supporting crucial GO / NO-GO decisions throughout the drug discovery process.

Our proprietary work-flow provides comprehensive information about both the target and the action mechanism of bioactive molecules, via a unique combination of chemical biology, biophysics and cell & molecular biology methods.

By identifying fewer - yet rightful - targets and avoiding the validation of false positives, we help you save time and money during the drug discovery process.

We have successfully identified cytoplasmic (ie. kinases), membrane (ie. GPCRs) and nuclear targets.

Certifications:
1) The Global Commercialization Group at the IC2 Institute, University of Texas at Austin
2) Department of Biotech (DBT), Govt. of India: Approved and Supported
3) Technology Board of India (TBD): Approved & Supported

Relevant publications & patents:
- Provisional Patents 645/MUM/2011, 975/MUM/2012
- Saxena C., Affinity-Based Chemoproteomics with Small Molecule-Peptide Conjugates , Methods Mol Biol (2012) 803 pp. 39-54.
- Saxena et al, Capture of Drug Targets from Live Cells Using a Multipurpose Immuno-Chemo-Proteomics Tool , J. Proteome Res. (2009) 8 pp. 3951-3957.
- Saxena C., Small-molecule affinity chromatography coupled mass spectrometry for drug target deconvolution , Expert Opinion on Drug Discovery (2009) 4 pp. 701- 714.
- Saxena et al, An Immuno-Chemo-Proteomics Method for Drug Target Deconvolution , J. Proteome Res. (2008) 7 pp. 3490-3497.

Standard shipping requests:
We have a tie-up with WorldCourier for shipping samples (molecule, cell-lines) to our labs.
OR
Client may use their choice of partners to send the samples to our labs

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Our Services (6)


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Drug Target Identification

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Drug Mechanism of Action Studies

Mechanism of Action Studies
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Drug Discovery

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Drug Discovery & Development

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Lead Identification and Validation

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Medicinal Chemistry

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Adi Ghosh

Global Business Development & Liaison Principal

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