Selvita

About Selvita

Founded: 2007 Type: Public Company Size: 201-500 employees

Selvita is a pre-clinical CRO and drug discovery company founded in 2007 in Krakow, Poland. We offer support for drug discovery development at every stage of the early discovery phase up to the preclinical research.

The company was established in 2007 and currently employs over 360 scientists, among which... Show more »

The company was established in 2007 and currently employs over 360 scientists, among which 30% are PhDs.

Selvita's laboratories are located in Krakow, Poland and possess both GLP and GMP certification. Drug discovery clients of Selvita include more than fifty large and medium-sized pharmaceutical and biotechnology companies from USA and Europe.

Selvita offers integrated drug discovery projects helping biotech and pharma partners discover and develop new drugs. Our scientists have an extensive experience in several areas of life sciences, and we offer the following types of projects:

Contract chemistry services: medicinal chemistry, custom organic synthesis, scale-up and process chemistry, as well as industrial chemistry
Biology services: cell and molecular biology, ADME and pharmacokinetics, proteomic analyses, analytical chemistry and method validation
Integrated drug discovery projects combining variety of drug discovery processes from in silico drug design, and synthesis of a target-focused library, SAR and ADME-driven lead optimization and toxicity prediction, followed by complex preclinical in vitro development, all tailored to the customer’s needs
Comparative studies of biosimilar medicinal products, including a wide range of analytical services, as well as molecular biology and biochemistry assays, successfully applied in biosimilar drug development.

Selvita specializes in a broad spectrum of pharmacodynnamic in vitro studies used to analyze biosimilar product's activity in comparison to adequate reference compounds. We offer assays that are able to detect even minor changes in biological response to pharmacologically active substances.

Company offices are located in Cambridge, MA, San Francisco Bay Area in the USA as well as Krakow, Poland and Cambridge, UK.

Selvita also develops its own innovative drugs, which originate from research at Polish universities and later commercializes them with partners from the pharmaceutical industry. Currently company has focused its research and development efforts in the area of oncology.

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Certifications & Qualifications

cGMP GLP GMP

Our Services (147)

In vivo Bioavailability/Bioequivalence Studies

Price on request

About Selvita

Certifications & Qualifications

Our Services (147)

In vivo Bioavailability/Bioequivalence Studies

Clinical Biomarkers

Compound Library Synthesis

Biomarker Analysis

Necrosis Assays

Residual Impurity Analysis

Apoptosis Assays

Cellular Metabolism Assays

Biopharmaceutical Development

Integrated Drug Discovery

In vitro ADME/DMPK Studies

X-ray Crystallography

Caspase Assays

PARP Cleavage Assay

Poly-(ADP-Ribose) Polymerase Cleavage Assay

In vitro PK/PD Studies

In vitro pharmacokinetics/pharmacodynamics

Surface Plasmon Resonance (SPR)

GC-FID

Gas Chromatography/Flame Ionization Detector

HPLC-DAD

High Performance Liquid Chromatography Coupled with Diode Array Detection

HPLC-MS/MS

High Performance Liquid Chromatography Coupled Tandem Mass Spectrometry

Fragment Screening

Cell-Based Compound Screening

Medicinal Chemistry

Computational Chemistry

Computational Modeling

Process and Scale-Up Chemistry

Process Consulting

Biopharmaceutical Characterization

Chemical Synthesis

Mutagenicity Testing

Activity Prediction

Structure Mining

Retrosynthetic Analysis and Synthetic Route Design

Drug Target Identification

Compound Library Design

QSAR Studies

Quantitative Structure-Activity Relationship Studies

In vivo Protein Binding Assays

Molecular Docking

Pharmacophore Modeling

Chemical Stability Testing

Custom Proteomics

CYP Inhibition Assay

In vitro Metabolic Stability Assays

Solubility and Dissolution Testing

LogP/LogD Determination

Drug Absorption Studies

Plasma Protein Binding

Radiometric Assays

Custom Cell-Based Assay Development

Cell Cycle Analysis

Analytical Method Development

Cleaning Validation Services

Compound Sourcing

Residual Solvent Analysis

Impurity Analysis

Regulatory Document Preparation and Submission

Pharmaceutical Formulation

Drug Preformulation

Chemical Analysis

eCTD Services

Recombinant Protein Expression

Protein Structure Determination

Design of Genetic Constructs

Hydrolyzed Amino Acid Analysis

Protein Crystallization Screening and Optimization

Electrophoretic Pattern Analysis

Hydrolyzed Amino Acid Analysis

Hit to Lead and Lead Optimization

Computational Drug Discovery

ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics