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Selvita

ic 8.0/10 Overall Rating 100% Positive
ic 1 Order Completed
Kraków, PL

About Selvita

Founded: 2007 Type: Public Company Size: 201-500 employees

Selvita is a pre-clinical CRO and drug discovery company founded in 2007 in Krakow, Poland. We offer support for drug discovery development at every stage of the early discovery phase up to the preclinical research.

The company was established in 2007 and currently employs over 360 scientists, among which... Show more »

Selvita is a pre-clinical CRO and drug discovery company founded in 2007 in Krakow, Poland. We offer support for drug discovery development at every stage of the early discovery phase up to the preclinical research.

The company was established in 2007 and currently employs over 360 scientists, among which 30% are PhDs.

Selvita's laboratories are located in Krakow, Poland and possess both GLP and GMP certification. Drug discovery clients of Selvita include more than fifty large and medium-sized pharmaceutical and biotechnology companies from USA and Europe.

Selvita offers integrated drug discovery projects helping biotech and pharma partners discover and develop new drugs. Our scientists have an extensive experience in several areas of life sciences, and we offer the following types of projects:

  • Contract chemistry services: medicinal chemistry, custom organic synthesis, scale-up and process chemistry, as well as industrial chemistry
  • Biology services: cell and molecular biology, ADME and pharmacokinetics, proteomic analyses, analytical chemistry and method validation
  • Integrated drug discovery projects combining variety of drug discovery processes from in silico drug design, and synthesis of a target-focused library, SAR and ADME-driven lead optimization and toxicity prediction, followed by complex preclinical in vitro development, all tailored to the customer’s needs
  • Comparative studies of biosimilar medicinal products, including a wide range of analytical services, as well as molecular biology and biochemistry assays, successfully applied in biosimilar drug development.

Selvita specializes in a broad spectrum of pharmacodynnamic in vitro studies used to analyze biosimilar product's activity in comparison to adequate reference compounds. We offer assays that are able to detect even minor changes in biological response to pharmacologically active substances.

Company offices are located in Cambridge, MA, San Francisco Bay Area in the USA as well as Krakow, Poland and Cambridge, UK.

Selvita also develops its own innovative drugs, which originate from research at Polish universities and later commercializes them with partners from the pharmaceutical industry. Currently company has focused its research and development efforts in the area of oncology.

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Certifications & Qualifications

cGMP GLP GMP

Our Services (148)


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In vivo Bioavailability/Bioequivalence Studies

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Clinical Biomarkers

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Compound Library Synthesis

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Biomarker Analysis

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Necrosis Assays

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Residual Impurity Analysis

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Apoptosis Assays

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Cellular Metabolism Assays

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Biopharmaceutical Development

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Integrated Drug Discovery

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In vitro ADME/DMPK Studies

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X-ray Crystallography

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Caspase Assays

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PARP Cleavage Assay

Poly-(ADP-Ribose) Polymerase Cleavage Assay
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In vitro PK/PD Studies

In vitro pharmacokinetics/pharmacodynamics
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Surface Plasmon Resonance (SPR)

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GC-FID

Gas Chromatography/Flame Ionization Detector
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HPLC-DAD

High Performance Liquid Chromatography Coupled with Diode Array Detection
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HPLC-MS/MS

High Performance Liquid Chromatography Coupled Tandem Mass Spectrometry
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Fragment Screening

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Cell-Based Compound Screening

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Medicinal Chemistry

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Computational Chemistry

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Computational Modeling

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Process and Scale-Up Chemistry

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Process Consulting

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Biopharmaceutical Characterization

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Chemical Synthesis

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gram milligram kilogram

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Mutagenicity Testing

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BrdU S-Phase Analysis

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Activity Prediction

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Structure Mining

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Retrosynthetic Analysis and Synthetic Route Design

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Drug Target Identification

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Compound Library Design

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QSAR Studies

Quantitative Structure-Activity Relationship Studies
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In vivo Protein Binding Assays

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Molecular Docking

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Pharmacophore Modeling

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Chemical Stability Testing

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Custom Proteomics

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CYP Inhibition Assay

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In vitro Metabolic Stability Assays

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Solubility and Dissolution Testing

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LogP/LogD Determination

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Drug Absorption Studies

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Plasma Protein Binding

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Radiometric Assays

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Custom Cell-Based Assay Development

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Cell Cycle Analysis

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Analytical Method Development

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Cleaning Validation Services

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Compound Sourcing

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Residual Solvent Analysis

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Impurity Analysis

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Regulatory Document Preparation and Submission

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Pharmaceutical Formulation

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Drug Preformulation

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Chemical Analysis

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eCTD Services

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Recombinant Protein Expression

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Protein Structure Determination

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Design of Genetic Constructs

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Hydrolyzed Amino Acid Analysis

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Protein Crystallization Screening and Optimization

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Electrophoretic Pattern Analysis

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Hydrolyzed Amino Acid Analysis

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Hit to Lead and Lead Optimization

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Computational Drug Discovery

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ADME/DMPK Studies

Drug Metabolism and Pharmacokinetics
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Metabolite Profiling

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MTT and MTS Assays

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Biochemical Assay Kits

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LDH Release Assay

Lactate Dehydrogenase Release Assay
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BrdU Assay

Bromodeoxyuridine Assay
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Assay Development

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REACH/TSCA Registration Support

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Mutagenicity Testing

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Cell-Based Assays

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Structural Biology

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Physical Analysis Methods

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Hit Identification

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Cells and Tissues

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Protein Services

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In vitro Bioavailability/Bioequivalence Studies

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Custom Gene Cloning

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Drug Discovery & Development

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Compound Libraries

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Safety Pharmacology

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Molecular Cloning

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DNA Services

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Spectroscopy

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Synchrotron Services

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Cellular Health & Metabolism Assays

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Liquid Chromatography (LC)

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Formulation Services

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Laboratory Equipment and Facility Management Services

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Protein Purification

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Cytotoxicity Assays

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Omics

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Chemistry and Materials

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Antibody/Antigen Detection Based Testing

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Metabolomics

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Imaging & Spectroscopy

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Biochemistry & Molecular Biology

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Biomolecular Interaction Analysis

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Regulatory Affairs Services

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Protein Sequencing

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Gel Electrophoresis

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Clinical Research

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Nucleic Acid Services

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Clinical Laboratory Services

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Analytical Chemistry Services

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Bioanalysis

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Liquid Chromatography Coupled Mass Spectrometry Methods

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Biochemical Assays

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Toxicology

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Synchrotron Data Collection

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Protein Production

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Protein Expression Optimization

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Mass Spectrometry

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Engineering and Fabrication

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Product Development, Testing, and Packaging

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Cell Death Assays

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Cytometry

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Cell Viability & Proliferation Assays

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Drug Discovery

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Lead Identification and Validation

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Chromatography

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Sterilization Services

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Electrophoresis

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Proteomics

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Biology

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Synthetic Chemistry

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Clinical Chemistry

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Separation/Purification Services

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Pharmacology & Toxicology

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Specialized Cell-Based Assays

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Project Management

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Drug Development

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Biomarkers

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Compound IC50 Assays

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Flow Cytometry

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Synchrotron Beamline Access

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Immunophenotyping

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Edman Degradation

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LC-MS

Liquid Chromatography-Coupled Mass Spectrometry
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Pharmacology

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Pharmacology Services

Pharmacology Services

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  • Positive review for N-Terminal Sequencing:

    January 2017

    "A excellent lob. Very responsive to question and help through out the entire process Very professionally, timely done. Excellent quality"

Selvita has not received any endorsements.