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Scripps Center for Metabolomics

La Jolla, CA, US

The Center for Metabolomics and Mass Spectrometry provides routine analyses as well as specialty applications for Scripps Research and outside biotechnology communities with a wide variety of ESI and MALDI approaches as well as GC/MS. The Center has several instruments available, including MALDI TOF, ESI quads, ESI TOF, ESI QTOF and ESI ion traps. We analyze a wide variety of compounds including small molecules, peptides, proteins and oligonucleotides. We also have a unique online sample submission that streamlines the process.

Recent Publications

  • Montenegro-Burke J. R., Aisporna A. E., Benton H. P., Rinehart D., Fang M., Huan T., Warth B., Forsberg E., Abe B. T., Ivanisevic J., Wolan D. W. , Teyton L., Lairson L., and Siuzdak G. Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes Analytical Chemistry 2017 PMC5244434
  • Warth B., Levin N., Rinehart D., Teijaro... Show more »

The Center for Metabolomics and Mass Spectrometry provides routine analyses as well as specialty applications for Scripps Research and outside biotechnology communities with a wide variety of ESI and MALDI approaches as well as GC/MS. The Center has several instruments available, including MALDI TOF, ESI quads, ESI TOF, ESI QTOF and ESI ion traps. We analyze a wide variety of compounds including small molecules, peptides, proteins and oligonucleotides. We also have a unique online sample submission that streamlines the process.

Recent Publications

  • Montenegro-Burke J. R., Aisporna A. E., Benton H. P., Rinehart D., Fang M., Huan T., Warth B., Forsberg E., Abe B. T., Ivanisevic J., Wolan D. W. , Teyton L., Lairson L., and Siuzdak G. Data Streaming for Metabolomics: Accelerating Data Processing and Analysis from Days to Minutes Analytical Chemistry 2017 PMC5244434
  • Warth B., Levin N., Rinehart D., Teijaro J., Benton H. P., Siuzdak G. Metabolizing Data in the Cloud Trends in Biotechnology 2017
  • Montenegro-Burke J. R., Phommavongsay T., Aisporna A.E., Huan T., Rinehart D., Forsberg E., Thorgersen M. P., Adams M. W. W., Northen T. R., Robbins P.D., Niedernhofer L. J., Lairson L., Benton H. P., Siuzdak G. Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses Analytical Chemistry 2016
  • Johnson C., Ivanisevic J., Siuzdak G. Metabolomics: Beyond Biomarkers and Towards Mechanisms Nature Reviews Molecular Cell Biology 2016
  • Kurihara K., Westenskow P., Gantner M., Usui Y., Schultz A., Bravo S., Aguilara E., Wittgrove C., SanGiovanni J., Friedlander M., Paris L., Chew E., Siuzdak G., Friedlander M. Hypoxia induced metabolic stress in RPE cells is sufficient to induce photoreceptor degeneration eLife 2016 PMC4848091
  • Wang J., Westenskow P., Fang M., Friedlander M., Siuzdak G. Quantitative Metabolomics of Photoreceptor Degeneration and the Effects of Stem Cell Derived RPE Transplantation Philosophical Transactions A 2016
  • Kurczy M., Forsberg E., Thorgersen M., Poole II F., Benton H.P., Ivanisevic J., Tran M., Wall J., Elias D., Adams M., Siuzdak G. Global Isotope Metabolomics Reveals Adaptive Strategies for Nitrogen Assimilation ACS Chemical Biology 2016
  • Ivanisevic J., Stauch K., Petrascheck. M., Benton H.P., Epstein A., Fang M., Gorantla S., Tran M., Hoang L., Boska M., Gendelman H., Fox H., Siuzdak G. Metabolic Drift in the Aging Brain Aging 2016 PMC4931850
  • Paris L., Johnson C., Aguilar E., Usui Y., Cho K., Hoang L., Feitelberg D., Benton H.P., Westenskow P., Kurihara T., Trombley J., Patti G., Ivanisevic J., Siuzdak G, Friedlander M. Global metabolomics reveals metabolic dysregulation in ischemic retinopathy Metabolomics 2016 PMC4651979
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Scripps Center for Metabolomics has not listed any services.

Mass Spectrometry
Price on request

Full service Mass Spectrometry analysis including Proteomics, protein ID, LC/MS, GC/MS, MALDI-TOF, ESI-QTOF, MS/MS, and custom methods.

Full service Mass Spectrometry analysis including Proteomics, protein ID, LC/MS, GC/MS, MALDI-TOF, ESI-QTOF, MS/MS, and custom methods.

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Metabolomics
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Proteomics
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Protein Identification
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We are equipped to identify proteins using a procedure that includes digestion, nano-LC/MS/MS analysis and database searching.

We are equipped to identify proteins using a procedure that includes digestion, nano-LC/MS/MS analysis and database searching.

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LC-MS
Liquid Chromatography-Coupled Mass Spectrometry
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GC-MS
Gas Chromatography Coupled Mass Spectrometry
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GC/MS is best for compounds that easily vaporize and are kept in volatile solvents. Another advantage is that your results can be compared to GC/MS data from the NIST database.

GC/MS is best for compounds that easily vaporize and are kept in volatile solvents. Another advantage is that your results can be compared to GC/MS data from the NIST database.

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MALDI TOF MS
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
Price on request

ESI-TOF provides unit mass in both positive or negative ionization modes. MALDI-TOF can provide up to unit mass results on small oligonucleotides, proteins, and polymers.

ESI-TOF provides unit mass in both positive or negative ionization modes. MALDI-TOF can provide up to unit mass results on small oligonucleotides, proteins, and polymers.

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ESI-TOF-MS
Electrospray ionization time of flight mass spectrometry
Price on request

ESI-TOF provides unit mass in both positive or negative ionization modes. MALDI-TOF can provide up to unit mass results on small oligonucleotides, proteins, and polymers.

ESI-TOF provides unit mass in both positive or negative ionization modes. MALDI-TOF can provide up to unit mass results on small oligonucleotides, proteins, and polymers.

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MS-MS
Tandem Mass Spectrometry
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