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SB Drug Discovery

Glasgow, GB

SB Drug Discovery is contract research services company offering expertise in screening of ion channels, PDEs, GPCRs and nuclear receptors.

Our ion channel portfolio consists of over 150 recombinant cell lines for HTS, lead optimization and selectivity profiling using a range of platforms including fluorescence and both manual and automated patch clamp electrophysiology. Our cell line portfolio is constantly expanding and custom cell lines can be made to suit your needs.

SB also specializes in screening assays against PDEs, GPCRs and other drug targets. Our PDE panel contains over 40 human and animal isoforms which are available for screening by fluorescence and the gold standard radiometric assay. GPCR assays include radioligand binding and functional cell based assays.

A comprehensive panel of inflammatory assays are also offered using fresh human blood, either as whole blood, PBMCs or isolated cell types.... Show more »

SB Drug Discovery is contract research services company offering expertise in screening of ion channels, PDEs, GPCRs and nuclear receptors.

Our ion channel portfolio consists of over 150 recombinant cell lines for HTS, lead optimization and selectivity profiling using a range of platforms including fluorescence and both manual and automated patch clamp electrophysiology. Our cell line portfolio is constantly expanding and custom cell lines can be made to suit your needs.

SB also specializes in screening assays against PDEs, GPCRs and other drug targets. Our PDE panel contains over 40 human and animal isoforms which are available for screening by fluorescence and the gold standard radiometric assay. GPCR assays include radioligand binding and functional cell based assays.

A comprehensive panel of inflammatory assays are also offered using fresh human blood, either as whole blood, PBMCs or isolated cell types. SB has vast expertise in inflammatory drug discovery and can customize assays to match your needs.

With over 20 years' experience servicing a worldwide client base in the areas of molecular & cellular biology, protein expression, assay development, screening and in vivo pharmacology, our 3 focused scientists hold the potential to enhance your drug discovery programs.

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SB Drug Discovery has not listed any services.

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Ion Channel Screening Assays
Price on request

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

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hERG
Cav1.2
TRP channels
calcium channels
GABA receptors
nicotinic receptors
glutamate receptors
potassium channels
p2x receptors
voltage gated sodium channels
voltage gated calcium channels
Nav
Cav
Voltage-Gated Ion Channel Assays
Price on request

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

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potassium channels
Voltage gated sodium channels
voltage gated calcium channels
potassium channels
sodium channels
calcium channels
voltage gated sodium channels
voltage gated calcium channels
Nav
Cav
Kv
Cellular Ion Channel Assays
Price on request

Over 150 cell-based ion channel electrophysiology assays available

Over 150 cell-based ion channel electrophysiology assays available

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Ion Channel
electrophysiology
Fluorescence
Syncropatch
manual patch clamp
FLIPR
sodium channels
TRP channels
calcium channels
GABA receptors
nicotinic receptors
glutamate receptors
potassium channels
p2x receptors
Nav
Cav
Kv
Patch clamp electrophysiology
Cell Electrophysiology
Price on request

Manual and automated electrophysiology services, over 150 ion channel targets & assays

Manual and automated electrophysiology services, over 150 ion channel targets & assays

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Ion Channel
Syncropatch
manual patch clamp
sodium channels
TRP channels
calcium channels
GABA receptors
nicotinic receptors
glutamate receptors
potassium channels
p2x receptors
Nav
Cav
Kv
Patch Clamp Recording
Price on request

Manual and automated patch clamp electrophysiology services. Rapidly screen compounds against a choice of over 150 recombinant ion channel cell lines.

Manual and automated patch clamp electrophysiology services. Rapidly screen compounds against a choice of over 150 recombinant ion channel cell lines.

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electrophysiology
Manual patch clamp
automated patch clamp
Syncropatch
manual patch clamp
FLIPR
Recombinant cell lines
sodium channels
TRP channels
calcium channels
GABA receptors
nicotinic receptors
glutamate receptors
potassium channels
p2x receptors
Cell Line Products - Ion Channels
Price on request

Access SB's portfolio of over 80 ion channel cell lines - validated by electrophysiology

Access SB's portfolio of over 80 ion channel cell lines - validated by electrophysiology

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Stable Cell Line Generation
Price on request

SB has developed over 250 ion channel and GPCR cell lines. Let us utilize our experience and expertise to develop cell lines that meet your needs.

SB has developed over 250 ion channel and GPCR cell lines. Let us utilize our experience and expertise to develop cell lines that meet your needs.

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Cell line engineering
cell line generation
cell line development
In vitro Inflammation Models
Price on request

SB specializes in inflammatory drug discovery and uses fresh human blood for all studies. Assays utilize whole blood, PBMCs or any isolated cell type for assessment of cytokine levels. SB has over 20 years experience in inflammation and can design assays specifically for your needs.

SB specializes in inflammatory drug discovery and uses fresh human blood for all studies. Assays utilize whole blood, PBMCs or any isolated cell type for assessment of cytokine levels. SB has over 20 years experience in inflammation and can design assays specifically for your needs.

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Whole blood
inflammatory
skin inflammation
Inflammation
lymphocytes
inflammation
pmbc
granulocytes
T cells
inflam
Anti-Inflammatory Drug Screening in Human Cells
Price on request

Cytokine profiling of freshly isolated, stimulated, whole blood, PBMCs and fractionated cell types.

Cytokine profiling of freshly isolated, stimulated, whole blood, PBMCs and fractionated cell types.

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Human
Whole blood
inflammatory
pbmc
skin inflammation
Inflammation
lymphocytes
inflammation
PBMC's
neutrophils
Cytokine Release Assay
Price on request

Assessment of cytokine levels in stimulated whole blood, PBMCs and fractionated cell types

Assessment of cytokine levels in stimulated whole blood, PBMCs and fractionated cell types

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Human
Whole blood
inflammatory
pbmc
skin inflammation
Inflammation
lymphocytes
inflammation
PBMC's
neutrophils
Neutrophil Oxidative Burst Assay
Price on request

Oxidative burst assay using freshly isolated human granulocytes.

Oxidative burst assay using freshly isolated human granulocytes.

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Human
Whole blood
inflammatory
skin inflammation
Inflammation
inflammation
pmbc
granulocytes
Phosphodiesterase (PDE) Assays
Price on request

Over 40 human and animal PDE isoforms available for HTS, lead optimization and selectivity profiling. SB has over 20 years experience in the field of PDE drug discovery encompassing both biochemical and cell-based PDE assays.

Over 40 human and animal PDE isoforms available for HTS, lead optimization and selectivity profiling. SB has over 20 years experience in the field of PDE drug discovery encompassing both biochemical and cell-based PDE assays.

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inflammatory
CNS/Neurology
skin inflammation
Inflammation
Respiratory
Phosphodiesterase
PDE1
PDE2
PDE3
PDE4
PDE5
PDE6
PDE7
PDE8
PDE9
PDE10
PDE11
GPCR Screening and Profiling
Price on request

SB offers radioligand binding and cell based assays against a broad range of GPCR targets.

SB offers radioligand binding and cell based assays against a broad range of GPCR targets.

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Cell-based assays
GPCR
radioligand binding
calcium flux
cAMP assay
adenosine receptors
5HT receptors
dopamine receptors
adrenergic receptors
muscarinic receptors
Biochemical Assays
Price on request
Request a quote for more information about this service.
Cell-Based Assays
Price on request
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Cell-Based Screening Methods
Price on request
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Assay Development
Price on request
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Biochemistry & Molecular Biology
Price on request
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Cell and Tissue Culture
Price on request
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In vitro Disease Models
Price on request
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Biology
Price on request
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Cell Lines
Price on request
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Immunoassays
Price on request

Immunoassays Services

Immunoassays Services

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Enzyme Assays
Price on request
Request a quote for more information about this service.
Mammalian Cell Culture
Price on request

Mammalian Cell Culture Services

Mammalian Cell Culture Services

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Live Cell Assay Development
Price on request
Request a quote for more information about this service.
Protein Expression in Mammalian Cells
Mammalian cell based recombinant protein production
Price on request
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Respiratory Burst Assay
Price on request

Superoxide release assay using freshly isolated human granulocytes

Superoxide release assay using freshly isolated human granulocytes

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Human
Whole blood
inflammatory
skin inflammation
Inflammation
inflammation
PBMC's
pmbc
granulocytes
Electrophysiology
Price on request

Electrophysiology Services

Electrophysiology Services

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July 26, 2018

Positive review received for Ion Channel Screening Assays:

"Overall an excellent experience. SB Drug Discovery ran into some technical difficulties requiring additional experiments to generate a reliable data set. SB Drug Discovery was very proactive in suggesting these experiments and communicating the changes in timelines and protocol. The report was very comprehensive."

2018-06-11 12:55:27 -0400

Net Promoter Score of 5 received for Patch Clamp Recording.

Additional Ratings: satisfaction with deliverable: 5, satisfaction with timeliness: 8.
2018-06-08 11:05:42 -0400

Net Promoter Score of 8 received for Ion Channel Screening Assays.

Additional Ratings: satisfaction with deliverable: 8, satisfaction with timeliness: 8.
2017-02-23 13:20:58 -0500

Net Promoter Score of 5 received for Stable Cell Line Generation.

Additional Ratings: satisfaction with deliverable: 5, satisfaction with timeliness: 5.

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