Fnd1pclmshmr72xuc4dz screen shot 2014 12 05 at 10.17.19 am

SB Drug Discovery

ic 7.2/10 Overall Rating 71% Positive
ic 19 Orders Completed
Glasgow, GB

About SB Drug Discovery

Founded: 1994 Type: Privately Held Size: 11-50 employees

SB Drug Discovery is contract research services company offering expertise in screening of ion channels, PDEs, GPCRs and nuclear receptors.

Our ion channel portfolio consists of over 150 recombinant cell lines for HTS, lead optimization and selectivity profiling using a range of platforms including... Show more »

SB Drug Discovery is contract research services company offering expertise in screening of ion channels, PDEs, GPCRs and nuclear receptors.

Our ion channel portfolio consists of over 150 recombinant cell lines for HTS, lead optimization and selectivity profiling using a range of platforms including fluorescence and both manual and automated patch clamp electrophysiology. Our cell line portfolio is constantly expanding and custom cell lines can be made to suit your needs.

SB also specializes in screening assays against PDEs, GPCRs and other drug targets. Our PDE panel contains over 40 human and animal isoforms which are available for screening by fluorescence and the gold standard radiometric assay. GPCR assays include radioligand binding and functional cell based assays.

A comprehensive panel of inflammatory assays are also offered using fresh human blood, either as whole blood, PBMCs or isolated cell types. SB has vast expertise in inflammatory drug discovery and can customize assays to match your needs.

With over 20 years' experience servicing a worldwide client base in the areas of molecular & cellular biology, protein expression, assay development, screening and in vivo pharmacology, our 3 focused scientists hold the potential to enhance your drug discovery programs.

Show less

Our Services (43)


ic

Ion Channel Screening Assays

Price on request

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Show less
hERG Cav1.2 TRP channels calcium channels GABA receptors nicotinic receptors glutamate receptors potassium channels p2x receptors voltage gated sodium channels voltage gated calcium channels Nav Cav Show 13 more tags Show less

ic

Voltage-Gated Ion Channel Assays

Price on request

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Access our panel of over 150 ion channel cell lines and validated ion channel screening assays.

Show less
Voltage gated sodium channels voltage gated calcium channels potassium channels sodium channels calcium channels potassium channels voltage gated sodium channels voltage gated calcium channels Nav Cav Kv Show 11 more tags Show less

ic

In vitro Ion Channel Assays

Price on request

Over 150 cell-based ion channel electrophysiology assays available

Over 150 cell-based ion channel electrophysiology assays available

Show less
electrophysiology Fluorescence Manual patch clamp FLIPR Patch clamp electrophysiology Ion Channel sodium channels TRP channels calcium channels GABA receptors nicotinic receptors glutamate receptors potassium channels p2x receptors Nav Cav Kv Syncropatch Show 18 more tags Show less

ic

Cell Electrophysiology

Price on request

Manual and automated electrophysiology services, over 150 ion channel targets & assays

Manual and automated electrophysiology services, over 150 ion channel targets & assays

Show less
Manual patch clamp Ion Channel sodium channels TRP channels calcium channels GABA receptors nicotinic receptors glutamate receptors potassium channels p2x receptors Nav Cav Kv Syncropatch Show 14 more tags Show less

ic

Patch Clamp Recording

Price on request

Manual and automated patch clamp electrophysiology services. Rapidly screen compounds against a choice of over 150 recombinant ion channel cell lines.

Manual and automated patch clamp electrophysiology services. Rapidly screen compounds against a choice of over 150 recombinant ion channel cell lines.

Show less
Recombinant cell lines electrophysiology Automated patch clamp Manual patch clamp FLIPR sodium channels TRP channels calcium channels GABA receptors nicotinic receptors glutamate receptors potassium channels p2x receptors Syncropatch Show 14 more tags Show less

ic

Cell Line Products - Ion Channels

Price on request

Access SB's portfolio of over 80 ion channel cell lines - validated by electrophysiology

Access SB's portfolio of over 80 ion channel cell lines - validated by electrophysiology

Show less

ic

Stable Cell Line Generation

Price on request

SB has developed over 250 ion channel and GPCR cell lines. Let us utilize our experience and expertise to develop cell lines that meet your needs.

SB has developed over 250 ion channel and GPCR cell lines. Let us utilize our experience and expertise to develop cell lines that meet your needs.

Show less
Cell line engineering cell line generation cell line development

ic

In vitro Inflammation Models

Price on request

SB specializes in inflammatory drug discovery and uses fresh human blood for all studies. Assays utilize whole blood, PBMCs or any isolated cell type for assessment of cytokine levels. SB has over 20 years experience in inflammation and can design assays specifically for your needs.

SB specializes in inflammatory drug discovery and uses fresh human blood for all studies. Assays utilize whole blood, PBMCs or any isolated cell type for assessment of cytokine levels. SB has over 20 years experience in inflammation and can design assays specifically for your needs.

Show less
Immunology Inflammation Whole blood lymphocytes pmbc granulocytes T cells Show 7 more tags Show less

ic

Anti-Inflammatory Drug Screening in Human Cells

Price on request

Cytokine profiling of freshly isolated, stimulated, whole blood, PBMCs and fractionated cell types.

Cytokine profiling of freshly isolated, stimulated, whole blood, PBMCs and fractionated cell types.

Show less
Human Inflammation Whole blood pbmc lymphocytes PBMC's neutrophils Show 7 more tags Show less

ic

Cytokine Release Assay

Price on request

Assessment of cytokine levels in stimulated whole blood, PBMCs and fractionated cell types

Assessment of cytokine levels in stimulated whole blood, PBMCs and fractionated cell types

Show less
Human Inflammation Whole blood pbmc lymphocytes PBMC's neutrophils Show 7 more tags Show less

ic

Neutrophil Oxidative Burst Assay

Price on request

Oxidative burst assay using freshly isolated human granulocytes.

Oxidative burst assay using freshly isolated human granulocytes.

Show less
Human Inflammation Whole blood pmbc granulocytes

ic

Phosphodiesterase (PDE) Assays

Price on request

Over 40 human and animal PDE isoforms available for HTS, lead optimization and selectivity profiling. SB has over 20 years experience in the field of PDE drug discovery encompassing both biochemical and cell-based PDE assays.

Over 40 human and animal PDE isoforms available for HTS, lead optimization and selectivity profiling. SB has over 20 years experience in the field of PDE drug discovery encompassing both biochemical and cell-based PDE assays.

Show less
CNS/Neurology Respiratory Inflammation Phosphodiesterase PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE8 PDE9 PDE10 PDE11 Show 15 more tags Show less

ic

GPCR Screening and Profiling

Price on request

SB offers radioligand binding and cell based assays against a broad range of GPCR targets.

SB offers radioligand binding and cell based assays against a broad range of GPCR targets.

Show less
Cell-based assays radioligand binding calcium flux cAMP assay GPCR adenosine receptors 5HT receptors dopamine receptors adrenergic receptors muscarinic receptors Show 10 more tags Show less

ic

Biochemical Assays

Price on request
Request a quote for more information about this service.

ic

Cell-Based Assays

Price on request
Request a quote for more information about this service.

ic

Cell-Based Screening Methods

Price on request
Request a quote for more information about this service.

ic

Assay Development

Price on request
Request a quote for more information about this service.

ic

Biochemistry & Molecular Biology

Price on request
Request a quote for more information about this service.

ic

Cell and Tissue Culture

Price on request
Request a quote for more information about this service.

ic

In vitro Disease Models

Price on request
Request a quote for more information about this service.

ic

Sequencing data in FASTQ

Price on request
Request a quote for more information about this service.

ic

Cell Lines

Price on request
Request a quote for more information about this service.

ic

Immunoassays

Price on request

Immunoassays Services

Immunoassays Services

Show less

ic

Enzyme Assays

Price on request
Request a quote for more information about this service.

ic

Mammalian Cell Culture

Price on request

Mammalian Cell Culture Services

Mammalian Cell Culture Services

Show less

ic

Live Cell Assay Development

Price on request
Request a quote for more information about this service.

ic

Protein Expression in Mammalian Cells

Mammalian cell based recombinant protein production
Price on request
Request a quote for more information about this service.

ic

Respiratory Burst Assay

Price on request

Superoxide release assay using freshly isolated human granulocytes

Superoxide release assay using freshly isolated human granulocytes

Show less
Human Inflammation Whole blood PBMC's pmbc granulocytes Show 6 more tags Show less

ic

Compound Profiling

Price on request
Request a quote for more information about this service.

ic

Drug Discovery & Development

Price on request

Drug Discovery & Development Services

Drug Discovery & Development Services

Show less

ic

Drug Discovery

Price on request

Drug Discovery Services

Drug Discovery Services

Show less

ic

Lead Identification and Validation

Price on request

Lead Identification and Validation Services

Lead Identification and Validation Services

Show less

ic

Whole Blood Assays

Price on request
Request a quote for more information about this service.

ic

In vitro Cardiotoxicity Screening

Price on request
Request a quote for more information about this service.

ic

Toxicology

Price on request

Toxicology Services

Toxicology Services

Show less

ic

In vitro Toxicity Testing

Price on request

In vitro Toxicity Testing Services

In vitro Toxicity Testing Services

Show less

ic

Testing of Cell Lines

Price on request
Request a quote for more information about this service.

ic

Custom Cell-Based Assay Development

Price on request
Request a quote for more information about this service.

ic

Specialized Cell-Based Assays

Price on request

Specialized Cell-Based Assays Services

Specialized Cell-Based Assays Services

Show less

ic

Membrane Protein Expression

Price on request
Request a quote for more information about this service.

ic

Baculovirus/Insect Cell Protein Expression

Price on request
Request a quote for more information about this service.

ic

hERG Channel Inhibition Assay

Price on request
Request a quote for more information about this service.

ic

Electrophysiology

Price on request

Electrophysiology Services

Electrophysiology Services

Show less

Not finding what you're looking for?

Get info on this provider's capabilities without requesting a quote.
Missing Avatar

David Dalrymple

Director
  • Positive review for Ion Channel Screening Assays:

    September 2018

    "SB Drug Discovery completed a profiling panel for us. The data came in in half the time I had expected and looked great."

  • Positive review for Ion Channel Screening Assays:

    July 2018

    "Overall an excellent experience. SB Drug Discovery ran into some technical difficulties requiring additional experiments to generate a reliable data set. SB Drug Discovery was very proactive in suggesting these experiments and communicating the changes in timelines and protocol. The report was very comprehensive."

SB Drug Discovery has not received any endorsements.