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Sanaria Inc.

Rockville, Maryland, US

Sanaria's primary mission is to develop and commercialize whole-parasite sporozoite vaccines that confer high-level, long-lasting protection against Plasmodium falciparum, the malaria parasite responsible for more than 95% of malaria associated severe illness and death world-wide and the malaria parasite for which there is the most significant drug resistance.

Recent Publications:

  • SH Sheehy et al, 'Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe', PLOS ONE, 2013
  • CR Garcia et al, 'Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine', Vaccine, 2013
  • M Rostenberg et al, 'Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites', AJTMH,... Show more »

Sanaria's primary mission is to develop and commercialize whole-parasite sporozoite vaccines that confer high-level, long-lasting protection against Plasmodium falciparum, the malaria parasite responsible for more than 95% of malaria associated severe illness and death world-wide and the malaria parasite for which there is the most significant drug resistance.

Recent Publications:

  • SH Sheehy et al, 'Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe', PLOS ONE, 2013
  • CR Garcia et al, 'Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine', Vaccine, 2013
  • M Rostenberg et al, 'Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites', AJTMH, 2013
  • AC Teirlinck et al, 'NF135.C10: A New Plasmodium falciparum Clone for Controlled Human Malaria Infections', JID, 2012
  • SH Adjalley et al, 'Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue', PNAS, 2011
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Plasmodium-Infected Mosquitoes
Price on request

Quantities of mosquitoes.


Live, aseptic and non-aseptic P. falciparum infected mosquitoes. These well-characterized mosquitoes are for experimentally challenging volunteers in studies assessing malaria vaccines and drugs and for laboratory-based research.

Quantities of mosquitoes.


Live, aseptic and non-aseptic P. falciparum infected mosquitoes. These well-characterized mosquitoes are for experimentally challenging volunteers in studies assessing malaria vaccines and drugs and for laboratory-based research.

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Mosquito
Recombinant Antibody Production
Price on request

Monoclonal and/or polyclonal antibodies are available against PfCelTOS, PfEXP-1, PfCSP, PvCSP, and Pf sporozoites.

Monoclonal and/or polyclonal antibodies are available against PfCelTOS, PfEXP-1, PfCSP, PvCSP, and Pf sporozoites.

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Recombinant Protein Expression
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The following purified recombinant proteins are available: PfCSP, PvCSP, PfCelTOS, PvCelTOS, PyCelTOS, PfSSP2/TRAP, PfLSA-1, PfEXP-1, PfEBA-175, PyCSP.

The following purified recombinant proteins are available: PfCSP, PvCSP, PfCelTOS, PvCelTOS, PyCelTOS, PfSSP2/TRAP, PfLSA-1, PfEXP-1, PfEBA-175, PyCSP.

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Plasmodium Assays
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Assessment of the effects of antibodies and drugs on the capacity of P. falciparum and P. vivax sporozoites to invade and develop in hepatocytes (inhibition of liver stage development assay), and of P. falciparum gametocytes to develop to oocysts and sporozoites in mosquitoes (transmission blocking assay). Assessment of... Show more »

Assessment of the effects of antibodies and drugs on the capacity of P. falciparum and P. vivax sporozoites to invade and develop in hepatocytes (inhibition of liver stage development assay), and of P. falciparum gametocytes to develop to oocysts and sporozoites in mosquitoes (transmission blocking assay). Assessment of antibodies to all life cycle stages of Plasmodium species by immunofluoresence assays and to selected antigens by ELISA.

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Plasmodium falciparum
Custom Cell-Based Assays
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Sanaria will manufacture Plasmodium species reagents to meet your specifications:

Anopheles Reagents

  • Aseptic and non-aseptic Anopheles stephensi mosquitoes and derived material for laboratory-based research studies.

Plasmodium Reagent Slides

  • Slides for immunofluorescence assays to detect antibodies against purified... Show more »

Sanaria will manufacture Plasmodium species reagents to meet your specifications:

Anopheles Reagents

  • Aseptic and non-aseptic Anopheles stephensi mosquitoes and derived material for laboratory-based research studies.

Plasmodium Reagent Slides

  • Slides for immunofluorescence assays to detect antibodies against purified sporozoite, and asexual erythrocytic, sexual erythrocytic and/or mosquito stages of Plasmodium species.

Plasmodium Reagents

  • Purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium species sporozoites, as well as other life cycle stages for laboratory-based research studies.

Plasmodium falciparum Sporozoite Reagents

  • Aseptic, purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium falciparum (Pf) sporozoites.
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Mosquito
Plasmodium falciparum
Animal Models and Studies
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Model Organisms
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Invertebrate Models
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Biology
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Cell-Based Assays
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Specialized Cell-Based Assays
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Cells and Tissues
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In vitro Disease Models
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Biochemistry & Molecular Biology
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Protein Services
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Protein Expression
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Antibody Services
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Therapeutic Monoclonal Antibody (mAb) Development
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