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Sanaria Inc.

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Rockville, Maryland, US

About Sanaria Inc.

Founded: 2003 Type: Privately Held Size: 11-50 employees

Sanaria's primary mission is to develop and commercialize whole-parasite sporozoite vaccines that confer high-level, long-lasting protection against Plasmodium falciparum, the malaria parasite responsible for more than 95% of malaria associated severe illness and death world-wide and the malaria parasite... Show more »

Sanaria's primary mission is to develop and commercialize whole-parasite sporozoite vaccines that confer high-level, long-lasting protection against Plasmodium falciparum, the malaria parasite responsible for more than 95% of malaria associated severe illness and death world-wide and the malaria parasite for which there is the most significant drug resistance.

Recent Publications:

  • SH Sheehy et al, 'Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe', PLOS ONE, 2013
  • CR Garcia et al, 'Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine', Vaccine, 2013
  • M Rostenberg et al, 'Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites', AJTMH, 2013
  • AC Teirlinck et al, 'NF135.C10: A New Plasmodium falciparum Clone for Controlled Human Malaria Infections', JID, 2012
  • SH Adjalley et al, 'Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue', PNAS, 2011
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Our Services (18)


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Plasmodium-Infected Mosquitoes

Price on request

Quantities of mosquitoes.


Live, aseptic and non-aseptic P. falciparum infected mosquitoes. These well-characterized mosquitoes are for experimentally challenging volunteers in studies assessing malaria vaccines and drugs and for laboratory-based research.

Quantities of mosquitoes.


Live, aseptic and non-aseptic P. falciparum infected mosquitoes. These well-characterized mosquitoes are for experimentally challenging volunteers in studies assessing malaria vaccines and drugs and for laboratory-based research.

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Insects

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Recombinant Antibody Production

Price on request

Monoclonal and/or polyclonal antibodies are available against PfCelTOS, PfEXP-1, PfCSP, PvCSP, and Pf sporozoites.

Monoclonal and/or polyclonal antibodies are available against PfCelTOS, PfEXP-1, PfCSP, PvCSP, and Pf sporozoites.

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Recombinant Protein Expression

Price on request

The following purified recombinant proteins are available: PfCSP, PvCSP, PfCelTOS, PvCelTOS, PyCelTOS, PfSSP2/TRAP, PfLSA-1, PfEXP-1, PfEBA-175, PyCSP.

The following purified recombinant proteins are available: PfCSP, PvCSP, PfCelTOS, PvCelTOS, PyCelTOS, PfSSP2/TRAP, PfLSA-1, PfEXP-1, PfEBA-175, PyCSP.

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Plasmodium Assays

Price on request

Assessment of the effects of antibodies and drugs on the capacity of P. falciparum and P. vivax sporozoites to invade and develop in hepatocytes (inhibition of liver stage development assay), and of P. falciparum gametocytes to develop to oocysts and sporozoites in mosquitoes (transmission blocking assay). Assessment of... Show more »

Assessment of the effects of antibodies and drugs on the capacity of P. falciparum and P. vivax sporozoites to invade and develop in hepatocytes (inhibition of liver stage development assay), and of P. falciparum gametocytes to develop to oocysts and sporozoites in mosquitoes (transmission blocking assay). Assessment of antibodies to all life cycle stages of Plasmodium species by immunofluoresence assays and to selected antigens by ELISA.

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Custom Cell-Based Assay Development

Price on request

Sanaria will manufacture Plasmodium species reagents to meet your specifications:

Anopheles Reagents

  • Aseptic and non-aseptic Anopheles stephensi mosquitoes and derived material for laboratory-based research studies.

Plasmodium Reagent Slides

  • Slides for immunofluorescence assays to detect antibodies against purified... Show more »

Sanaria will manufacture Plasmodium species reagents to meet your specifications:

Anopheles Reagents

  • Aseptic and non-aseptic Anopheles stephensi mosquitoes and derived material for laboratory-based research studies.

Plasmodium Reagent Slides

  • Slides for immunofluorescence assays to detect antibodies against purified sporozoite, and asexual erythrocytic, sexual erythrocytic and/or mosquito stages of Plasmodium species.

Plasmodium Reagents

  • Purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium species sporozoites, as well as other life cycle stages for laboratory-based research studies.

Plasmodium falciparum Sporozoite Reagents

  • Aseptic, purified, vialed, cryopreserved, attenuated and non-attenuated Plasmodium falciparum (Pf) sporozoites.
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Insects

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Protein Production

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In vitro Disease Models

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Protein Services

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Cells and Tissues

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Cell-Based Assays

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Biology

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Biochemistry & Molecular Biology

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Model Organisms

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Specialized Cell-Based Assays

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Antibody Services

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Therapeutic Monoclonal Antibody (mAb) Development

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Animal Models and Studies

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Invertebrate Models

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Alexander Hoffman

General Counsel

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